IL106408A - תולדות ביפנילמתיל 1 בנזאימידאזולים הכנתן ותכשירי רוקחות המכילים אותן - Google Patents
תולדות ביפנילמתיל 1 בנזאימידאזולים הכנתן ותכשירי רוקחות המכילים אותןInfo
- Publication number
- IL106408A IL106408A IL10640893A IL10640893A IL106408A IL 106408 A IL106408 A IL 106408A IL 10640893 A IL10640893 A IL 10640893A IL 10640893 A IL10640893 A IL 10640893A IL 106408 A IL106408 A IL 106408A
- Authority
- IL
- Israel
- Prior art keywords
- group
- methyl
- compound
- formula
- benzimidazol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4224133A DE4224133A1 (de) | 1992-07-22 | 1992-07-22 | Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL106408A0 IL106408A0 (en) | 1993-11-15 |
| IL106408A true IL106408A (he) | 1998-08-16 |
Family
ID=6463804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10640893A IL106408A (he) | 1992-07-22 | 1993-07-20 | תולדות ביפנילמתיל 1 בנזאימידאזולים הכנתן ותכשירי רוקחות המכילים אותן |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0581166A1 (he) |
| JP (1) | JPH06179659A (he) |
| KR (1) | KR940005584A (he) |
| CN (1) | CN1050122C (he) |
| AU (1) | AU675433B2 (he) |
| CA (1) | CA2100927A1 (he) |
| CZ (1) | CZ144993A3 (he) |
| DE (1) | DE4224133A1 (he) |
| FI (1) | FI933284A (he) |
| HU (1) | HUT64955A (he) |
| IL (1) | IL106408A (he) |
| MX (1) | MX9304424A (he) |
| NO (1) | NO300772B1 (he) |
| NZ (1) | NZ248217A (he) |
| PL (1) | PL172929B1 (he) |
| RU (1) | RU2126401C1 (he) |
| SG (1) | SG43083A1 (he) |
| SK (1) | SK73293A3 (he) |
| TW (1) | TW229207B (he) |
| ZA (1) | ZA93529B (he) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4233590A1 (de) * | 1992-10-06 | 1994-04-07 | Thomae Gmbh Dr K | Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| DE4304455A1 (de) * | 1993-02-15 | 1994-08-18 | Bayer Ag | Heterocyclisch substituierte Phenyl-cyclohexan-carbonsäurederivate |
| DE4324580A1 (de) * | 1993-07-22 | 1995-01-26 | Thomae Gmbh Dr K | Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| DK0882718T3 (da) * | 1995-12-28 | 2005-12-12 | Astellas Pharma Inc | Benzimidazolderivater |
| TW453999B (en) * | 1997-06-27 | 2001-09-11 | Fujisawa Pharmaceutical Co | Benzimidazole derivatives |
| HU222773B1 (hu) * | 2000-04-21 | 2003-10-28 | Richter Gedeon Vegyészeti Gyár Rt. | Eljárás egy ismert tetrazolszármazék előállítására |
| JPWO2005011736A1 (ja) * | 2003-07-30 | 2006-09-14 | 株式会社 東北テクノアーチ | アルツハイマー病の予防および／または治療剤 |
| CN101891735B (zh) * | 2009-11-25 | 2012-07-18 | 北京理工大学 | 联苯磺胺异噁唑类化合物、合成方法及用途 |
| CN101921265B (zh) * | 2009-11-25 | 2012-07-04 | 北京理工大学 | 联苯酰胺四唑类化合物、合成方法及用途 |
| CA2852964A1 (en) * | 2011-11-03 | 2013-05-10 | F. Hoffmann-La Roche Ag | Bicyclic piperazine compounds |
| CN105820125B (zh) * | 2015-01-09 | 2018-12-07 | 北京中医药大学 | 一种用于治疗高血压的化合物及其制备方法和用途 |
| CN105384729B (zh) * | 2015-07-09 | 2019-02-19 | 天津青松华药医药有限公司 | 替米沙坦酯类衍生物及其制备方法与应用 |
| CN106749220B (zh) * | 2017-01-18 | 2019-08-06 | 东华大学 | 一种6’-取代苯并咪唑-4-取代甲基吲哚衍生物及其制备和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3928177A1 (de) * | 1989-04-08 | 1991-02-28 | Thomae Gmbh Dr K | Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| RU1836357C (ru) * | 1990-07-23 | 1993-08-23 | Др.Карл Томэ ГмбХ | Производные бензимидазола, их изомеры, смеси изомеров, гидраты или их физиологически переносимые соли, обладающие антагонистическими в отношении ангиотензина свойствами |
| SI9210098B (sl) * | 1991-02-06 | 2000-06-30 | Dr. Karl Thomae | Benzimidazoli, zdravila, ki te spojine vsebujejo, in postopek za njihovo pripravo |
| DE4237656A1 (de) * | 1992-06-13 | 1993-12-16 | Merck Patent Gmbh | Benzimidazolderivate |
-
1992
- 1992-07-22 DE DE4224133A patent/DE4224133A1/de not_active Withdrawn
-
1993
- 1993-06-12 TW TW082104675A patent/TW229207B/zh active
- 1993-07-12 SK SK732-93A patent/SK73293A3/sk unknown
- 1993-07-20 EP EP93111581A patent/EP0581166A1/de not_active Ceased
- 1993-07-20 CA CA002100927A patent/CA2100927A1/en not_active Abandoned
- 1993-07-20 IL IL10640893A patent/IL106408A/he not_active IP Right Cessation
- 1993-07-20 SG SG1996003403A patent/SG43083A1/en unknown
- 1993-07-20 CN CN93108085A patent/CN1050122C/zh not_active Expired - Fee Related
- 1993-07-20 CZ CZ931449A patent/CZ144993A3/cs unknown
- 1993-07-21 AU AU42094/93A patent/AU675433B2/en not_active Expired
- 1993-07-21 PL PL93299754A patent/PL172929B1/pl unknown
- 1993-07-21 NZ NZ248217A patent/NZ248217A/en unknown
- 1993-07-21 FI FI933284A patent/FI933284A/fi unknown
- 1993-07-21 JP JP5179485A patent/JPH06179659A/ja active Pending
- 1993-07-21 ZA ZA93529A patent/ZA93529B/xx unknown
- 1993-07-21 KR KR1019930013764A patent/KR940005584A/ko not_active Application Discontinuation
- 1993-07-21 NO NO932636A patent/NO300772B1/no not_active IP Right Cessation
- 1993-07-21 HU HU9302115A patent/HUT64955A/hu unknown
- 1993-07-22 MX MX9304424A patent/MX9304424A/es unknown
- 1993-07-22 RU RU93049407A patent/RU2126401C1/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| EP0581166A1 (de) | 1994-02-02 |
| ZA93529B (en) | 1995-01-23 |
| HU9302115D0 (en) | 1993-10-28 |
| TW229207B (he) | 1994-09-01 |
| NO932636L (no) | 1994-01-24 |
| SG43083A1 (en) | 1997-10-17 |
| DE4224133A1 (de) | 1994-01-27 |
| CA2100927A1 (en) | 1994-01-23 |
| AU4209493A (en) | 1994-01-27 |
| FI933284A (fi) | 1994-01-23 |
| JPH06179659A (ja) | 1994-06-28 |
| CZ144993A3 (en) | 1994-03-16 |
| PL299754A1 (en) | 1994-03-21 |
| NO932636D0 (no) | 1993-07-21 |
| IL106408A0 (en) | 1993-11-15 |
| SK73293A3 (en) | 1994-04-06 |
| NO300772B1 (no) | 1997-07-21 |
| CN1050122C (zh) | 2000-03-08 |
| RU2126401C1 (ru) | 1999-02-20 |
| HUT64955A (en) | 1994-03-28 |
| CN1083812A (zh) | 1994-03-16 |
| NZ248217A (en) | 1996-06-25 |
| PL172929B1 (pl) | 1997-12-31 |
| AU675433B2 (en) | 1997-02-06 |
| FI933284A0 (fi) | 1993-07-21 |
| MX9304424A (es) | 1994-01-31 |
| KR940005584A (ko) | 1994-03-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| RH1 | Patent not in force |