IL104302A - Process for the preparation of 3-carboxy steroids using the Hello-Wilsmeier reagent - Google Patents

Process for the preparation of 3-carboxy steroids using the Hello-Wilsmeier reagent

Info

Publication number
IL104302A
IL104302A IL104302A IL10430293A IL104302A IL 104302 A IL104302 A IL 104302A IL 104302 A IL104302 A IL 104302A IL 10430293 A IL10430293 A IL 10430293A IL 104302 A IL104302 A IL 104302A
Authority
IL
Israel
Prior art keywords
reagent
process according
vilsmeier reagent
halogen
vilsmeier
Prior art date
Application number
IL104302A
Other languages
English (en)
Hebrew (he)
Other versions
IL104302A0 (en
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of IL104302A0 publication Critical patent/IL104302A0/xx
Publication of IL104302A publication Critical patent/IL104302A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL104302A 1992-01-06 1993-01-04 Process for the preparation of 3-carboxy steroids using the Hello-Wilsmeier reagent IL104302A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81717992A 1992-01-06 1992-01-06
US94134892A 1992-09-04 1992-09-04

Publications (2)

Publication Number Publication Date
IL104302A0 IL104302A0 (en) 1993-05-13
IL104302A true IL104302A (en) 1998-02-22

Family

ID=27124147

Family Applications (1)

Application Number Title Priority Date Filing Date
IL104302A IL104302A (en) 1992-01-06 1993-01-04 Process for the preparation of 3-carboxy steroids using the Hello-Wilsmeier reagent

Country Status (23)

Country Link
EP (1) EP0643723A4 (fr)
JP (1) JPH07505138A (fr)
KR (1) KR940703849A (fr)
CN (1) CN1077201A (fr)
AP (1) AP370A (fr)
AU (1) AU666167B2 (fr)
BG (1) BG98887A (fr)
BR (1) BR9305786A (fr)
CA (1) CA2127272A1 (fr)
CZ (1) CZ161994A3 (fr)
FI (1) FI943214A0 (fr)
HU (1) HUT68273A (fr)
IL (1) IL104302A (fr)
MA (1) MA22761A1 (fr)
MX (1) MX9300025A (fr)
NO (1) NO942535L (fr)
NZ (1) NZ246788A (fr)
OA (1) OA09961A (fr)
RU (1) RU94038223A (fr)
SI (1) SI9300006A (fr)
SK (1) SK80094A3 (fr)
TW (1) TW300226B (fr)
WO (1) WO1993014106A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641765A (en) * 1992-11-18 1997-06-24 Smithkline Beecham Corporation 17-αand 17-βsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-α-reductase
US5683995A (en) * 1992-11-18 1997-11-04 Smithkline Beecham Corporation 17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors
AU2005253966B2 (en) 2004-06-08 2012-01-19 Temple University Of The Commonwealth System Of Higher Education Heteroaryl sulfones and sulfonamides and therapeutic uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA883034B (en) * 1987-04-29 1989-03-29 Smithkline Beckman Corp Steroid 5-alpha-reductase inhibitors

Also Published As

Publication number Publication date
HU9402030D0 (en) 1994-09-28
AU666167B2 (en) 1996-02-01
TW300226B (fr) 1997-03-11
AP9300473A0 (en) 1993-01-31
AU3434893A (en) 1993-08-03
FI943214A (fi) 1994-07-05
SK80094A3 (en) 1994-12-07
FI943214A0 (fi) 1994-07-05
NO942535D0 (no) 1994-07-05
MX9300025A (es) 1994-01-31
MA22761A1 (fr) 1993-10-01
WO1993014106A1 (fr) 1993-07-22
OA09961A (en) 1995-12-11
AP370A (en) 1994-11-10
EP0643723A4 (fr) 1995-05-10
CN1077201A (zh) 1993-10-13
IL104302A0 (en) 1993-05-13
NZ246788A (en) 1996-11-26
SI9300006A (en) 1993-09-30
RU94038223A (ru) 1997-04-20
NO942535L (no) 1994-07-05
HUT68273A (en) 1995-06-28
BR9305786A (pt) 1997-02-18
KR940703849A (ko) 1994-12-12
CA2127272A1 (fr) 1993-07-22
EP0643723A1 (fr) 1995-03-22
CZ161994A3 (en) 1995-03-15
JPH07505138A (ja) 1995-06-08
BG98887A (bg) 1995-05-31

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Legal Events

Date Code Title Description
FF Patent granted
RH Patent void
MM9K Patent not in force due to non-payment of renewal fees