IL103603A - Proteins involved in the biosynthesis of an antibiotic polypeptide, a method for making the above proteins, and the DNA encoding them - Google Patents
Proteins involved in the biosynthesis of an antibiotic polypeptide, a method for making the above proteins, and the DNA encoding themInfo
- Publication number
- IL103603A IL103603A IL10360392A IL10360392A IL103603A IL 103603 A IL103603 A IL 103603A IL 10360392 A IL10360392 A IL 10360392A IL 10360392 A IL10360392 A IL 10360392A IL 103603 A IL103603 A IL 103603A
- Authority
- IL
- Israel
- Prior art keywords
- protein
- epi
- dna
- sequence
- host
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/90—Fusion polypeptide containing a motif for post-translational modification
- C07K2319/92—Fusion polypeptide containing a motif for post-translational modification containing an intein ("protein splicing")domain
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Epoxy Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78423491A | 1991-10-31 | 1991-10-31 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL103603A0 IL103603A0 (en) | 1993-03-15 |
| IL103603A true IL103603A (en) | 1999-12-31 |
Family
ID=25131778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10360392A IL103603A (en) | 1991-10-31 | 1992-10-30 | Proteins involved in the biosynthesis of an antibiotic polypeptide, a method for making the above proteins, and the DNA encoding them |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0543195B1 (no) |
| JP (1) | JP4117033B2 (no) |
| KR (1) | KR100242268B1 (no) |
| AT (1) | ATE162852T1 (no) |
| AU (1) | AU661054B2 (no) |
| CA (1) | CA2081704C (no) |
| CZ (2) | CZ286727B6 (no) |
| DE (1) | DE69224269T2 (no) |
| DK (1) | DK0543195T3 (no) |
| ES (1) | ES2112289T3 (no) |
| FI (1) | FI104498B (no) |
| GR (1) | GR3026465T3 (no) |
| HU (1) | HU215548B (no) |
| IL (1) | IL103603A (no) |
| MX (1) | MX9206265A (no) |
| NO (1) | NO307474B1 (no) |
| NZ (1) | NZ244976A (no) |
| ZA (1) | ZA928397B (no) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5639949A (en) * | 1990-08-20 | 1997-06-17 | Ciba-Geigy Corporation | Genes for the synthesis of antipathogenic substances |
| US5662898A (en) * | 1990-08-20 | 1997-09-02 | Ciba-Geigy Corporation | Genes for the synthesis of antipathogenic substances |
| US6117670A (en) * | 1994-06-08 | 2000-09-12 | Novartis Finance Corporation | Pyrrolnitrin biosynthesis genes and uses thereof |
| US6964760B2 (en) | 1997-06-10 | 2005-11-15 | University Of Florida Research Foundation | Antimicrobial polypeptide, nucleic acid, and methods of use |
| US5932469A (en) | 1997-06-10 | 1999-08-03 | University Of Florida | Antimicrobial polypeptide, nucleic acid, and methods of use |
| US6475771B1 (en) | 1997-06-10 | 2002-11-05 | University Of Florida Research Foundation | Antimicrobial polypeptides and methods of use |
| US6861236B2 (en) | 2002-05-24 | 2005-03-01 | Applied Nanosystems B.V. | Export and modification of (poly)peptides in the lantibiotic way |
| DE10261782A1 (de) * | 2002-12-19 | 2004-07-01 | Dr. Petry Genmedics Gmbh | Neue Gene und Genprodukte |
| CN101115838B (zh) | 2004-12-07 | 2015-08-12 | 莫菲西斯公司 | 产生和分泌修饰的肽的方法 |
| CN117511763A (zh) * | 2022-08-05 | 2024-02-06 | 天康制药股份有限公司 | 一种表皮葡萄球菌高密度发酵培养基及其发酵方法和应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8811761D0 (en) * | 1988-05-18 | 1988-06-22 | Thomae Gmbh Dr K | Biosynthetic process for preparation of chemical compounds |
-
1992
- 1992-10-29 KR KR1019920020041A patent/KR100242268B1/ko not_active IP Right Cessation
- 1992-10-29 FI FI924909A patent/FI104498B/fi not_active IP Right Cessation
- 1992-10-29 CA CA002081704A patent/CA2081704C/en not_active Expired - Lifetime
- 1992-10-30 HU HU9203434A patent/HU215548B/hu unknown
- 1992-10-30 DE DE69224269T patent/DE69224269T2/de not_active Expired - Lifetime
- 1992-10-30 CZ CS19923269A patent/CZ286727B6/cs not_active IP Right Cessation
- 1992-10-30 ZA ZA928397A patent/ZA928397B/xx unknown
- 1992-10-30 AU AU27459/92A patent/AU661054B2/en not_active Expired
- 1992-10-30 DK DK92118598T patent/DK0543195T3/da active
- 1992-10-30 CZ CZ963593A patent/CZ359396A3/cs not_active IP Right Cessation
- 1992-10-30 AT AT92118598T patent/ATE162852T1/de active
- 1992-10-30 EP EP92118598A patent/EP0543195B1/en not_active Expired - Lifetime
- 1992-10-30 MX MX9206265A patent/MX9206265A/es unknown
- 1992-10-30 IL IL10360392A patent/IL103603A/en not_active IP Right Cessation
- 1992-10-30 NO NO924192A patent/NO307474B1/no not_active IP Right Cessation
- 1992-10-30 ES ES92118598T patent/ES2112289T3/es not_active Expired - Lifetime
- 1992-11-02 JP JP31553392A patent/JP4117033B2/ja not_active Expired - Lifetime
- 1992-11-02 NZ NZ244976A patent/NZ244976A/en not_active IP Right Cessation
-
1998
- 1998-03-27 GR GR980400649T patent/GR3026465T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA928397B (en) | 1994-05-02 |
| MX9206265A (es) | 1994-05-31 |
| JP4117033B2 (ja) | 2008-07-09 |
| HUT65492A (en) | 1994-06-28 |
| HU215548B (hu) | 1999-01-28 |
| EP0543195A3 (en) | 1994-06-08 |
| KR100242268B1 (ko) | 2000-02-01 |
| NO307474B1 (no) | 2000-04-10 |
| JPH05292952A (ja) | 1993-11-09 |
| CZ326992A3 (en) | 1993-09-15 |
| AU661054B2 (en) | 1995-07-13 |
| DK0543195T3 (da) | 1998-09-23 |
| EP0543195A2 (en) | 1993-05-26 |
| NZ244976A (en) | 1995-07-26 |
| ATE162852T1 (de) | 1998-02-15 |
| CA2081704C (en) | 2007-05-01 |
| KR930008147A (ko) | 1993-05-21 |
| ES2112289T3 (es) | 1998-04-01 |
| NO924192L (no) | 1993-05-03 |
| EP0543195B1 (en) | 1998-01-28 |
| HU9203434D0 (en) | 1993-01-28 |
| CZ284861B6 (cs) | 1999-03-17 |
| FI924909A0 (fi) | 1992-10-29 |
| CZ359396A3 (cs) | 1999-03-17 |
| FI924909A (fi) | 1993-05-01 |
| DE69224269T2 (de) | 1998-06-04 |
| AU2745992A (en) | 1993-05-27 |
| NO924192D0 (no) | 1992-10-30 |
| CZ286727B6 (cs) | 2000-06-14 |
| FI104498B (fi) | 2000-02-15 |
| IL103603A0 (en) | 1993-03-15 |
| CA2081704A1 (en) | 1993-05-01 |
| DE69224269D1 (de) | 1998-03-05 |
| GR3026465T3 (en) | 1998-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |