IL103448A - Salts of the base 4-Amidino-1-Indanone-'2-Amidinohidzone, pharmaceutical preparations containing them and their preparation - Google Patents

Salts of the base 4-Amidino-1-Indanone-'2-Amidinohidzone, pharmaceutical preparations containing them and their preparation

Info

Publication number
IL103448A
IL103448A IL103448A IL10344892A IL103448A IL 103448 A IL103448 A IL 103448A IL 103448 A IL103448 A IL 103448A IL 10344892 A IL10344892 A IL 10344892A IL 103448 A IL103448 A IL 103448A
Authority
IL
Israel
Prior art keywords
acid
acids
formula
unsubstituted
indanone
Prior art date
Application number
IL103448A
Other languages
English (en)
Hebrew (he)
Other versions
IL103448A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL103448A0 publication Critical patent/IL103448A0/xx
Publication of IL103448A publication Critical patent/IL103448A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/18Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/16Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of hydrazones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/06One of the condensed rings being a six-membered aromatic ring the other ring being four-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cereal-Derived Products (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
IL103448A 1991-10-16 1992-10-15 Salts of the base 4-Amidino-1-Indanone-'2-Amidinohidzone, pharmaceutical preparations containing them and their preparation IL103448A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH304191 1991-10-16

Publications (2)

Publication Number Publication Date
IL103448A0 IL103448A0 (en) 1993-03-15
IL103448A true IL103448A (en) 1998-01-04

Family

ID=4247296

Family Applications (1)

Application Number Title Priority Date Filing Date
IL103448A IL103448A (en) 1991-10-16 1992-10-15 Salts of the base 4-Amidino-1-Indanone-'2-Amidinohidzone, pharmaceutical preparations containing them and their preparation

Country Status (24)

Country Link
EP (1) EP0538193B1 (ru)
JP (1) JP2788579B2 (ru)
KR (1) KR100265307B1 (ru)
AT (1) ATE145896T1 (ru)
AU (1) AU658931B2 (ru)
CA (1) CA2080545C (ru)
CY (1) CY2127B1 (ru)
CZ (1) CZ279601B6 (ru)
DE (1) DE59207617D1 (ru)
DK (1) DK0538193T3 (ru)
ES (1) ES2095444T3 (ru)
FI (1) FI112212B (ru)
GR (1) GR3021903T3 (ru)
HK (1) HK1005023A1 (ru)
HU (1) HU226954B1 (ru)
IL (1) IL103448A (ru)
MX (1) MX9205934A (ru)
NO (1) NO178108C (ru)
NZ (1) NZ244725A (ru)
RU (1) RU2081108C1 (ru)
SA (1) SA93130417B1 (ru)
SG (1) SG43185A1 (ru)
SK (1) SK279938B6 (ru)
ZA (1) ZA927957B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2103166B1 (es) * 1992-08-26 1998-04-01 Ciba Geigy Ag Procedimiento para la obtencion de amidinohidrazonas biciclicas.
DE69633557T2 (de) * 1995-01-26 2005-10-13 Novartis Ag Imdazol-derivate, deren herstellung und deren verwendung als s-adenosylmethionin decarboxylase (=samdc) inhibitoren
EP1483231A1 (de) * 2002-03-04 2004-12-08 Boehringer Ingelheim Pharma GmbH & Co.KG Neue salmeterol-zimtsäuresalze, verfahren zu deren herstellung und deren verwendung als arzneimittel
GT200600316A (es) * 2005-07-20 2007-04-02 Sales de 4-metilo-n-(3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo)-3-(4-piridina-3-ilo-pirimidina-2-iloamino)- benzamida.
EP1884515A1 (en) 2006-07-31 2008-02-06 Laboratorios del Dr. Esteve S.A. Substituted indanyl sulfonamide compounds, their preparation and use as medicaments

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU645799B2 (en) * 1990-05-07 1994-01-27 Novartis Ag Hydrazones

Also Published As

Publication number Publication date
IL103448A0 (en) 1993-03-15
HU226954B1 (en) 2010-03-29
SG43185A1 (en) 1997-10-17
FI112212B (fi) 2003-11-14
HUT63149A (en) 1993-07-28
DK0538193T3 (da) 1996-12-23
FI924650A (fi) 1993-04-17
MX9205934A (es) 1993-04-01
FI924650A0 (fi) 1992-10-14
NO924001D0 (no) 1992-10-15
HK1005023A1 (en) 1998-12-18
EP0538193B1 (de) 1996-12-04
GR3021903T3 (en) 1997-03-31
JPH05239011A (ja) 1993-09-17
CZ315292A3 (en) 1993-05-12
SK279938B6 (sk) 1999-06-11
NO924001L (no) 1993-04-19
AU658931B2 (en) 1995-05-04
NO178108C (no) 1996-01-24
JP2788579B2 (ja) 1998-08-20
EP0538193A3 (en) 1993-06-16
ATE145896T1 (de) 1996-12-15
AU2704092A (en) 1993-04-22
DE59207617D1 (de) 1997-01-16
SA93130417B1 (ar) 2005-11-12
CY2127B1 (en) 2002-06-21
HU9203234D0 (en) 1992-12-28
ZA927957B (en) 1993-04-26
NO178108B (no) 1995-10-16
RU2081108C1 (ru) 1997-06-10
CA2080545C (en) 2005-11-29
KR930007896A (ko) 1993-05-20
NZ244725A (en) 1995-05-26
EP0538193A2 (de) 1993-04-21
SK315292A3 (en) 1995-04-12
KR100265307B1 (ko) 2000-09-15
CZ279601B6 (cs) 1995-05-17
CA2080545A1 (en) 1993-04-17
ES2095444T3 (es) 1997-02-16

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Legal Events

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MM9K Patent not in force due to non-payment of renewal fees