IL102176A - Recombinant nucleic acid encoding a molecule - 3 for intercellular adhesion, functional history of 3ICAM and pharmaceutical preparations containing ICAM-3 or its functional history - Google Patents
Recombinant nucleic acid encoding a molecule - 3 for intercellular adhesion, functional history of 3ICAM and pharmaceutical preparations containing ICAM-3 or its functional historyInfo
- Publication number
- IL102176A IL102176A IL10217692A IL10217692A IL102176A IL 102176 A IL102176 A IL 102176A IL 10217692 A IL10217692 A IL 10217692A IL 10217692 A IL10217692 A IL 10217692A IL 102176 A IL102176 A IL 102176A
- Authority
- IL
- Israel
- Prior art keywords
- icam
- cells
- functional derivative
- lfa
- cell
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71287991A | 1991-06-11 | 1991-06-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL102176A0 IL102176A0 (en) | 1993-01-14 |
| IL102176A true IL102176A (en) | 2001-09-13 |
Family
ID=24863928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10217692A IL102176A (en) | 1991-06-11 | 1992-06-11 | Recombinant nucleic acid encoding a molecule - 3 for intercellular adhesion, functional history of 3ICAM and pharmaceutical preparations containing ICAM-3 or its functional history |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0590051A4 (pt) |
| JP (1) | JP3288042B2 (pt) |
| KR (2) | KR100333120B1 (pt) |
| CN (1) | CN1188528C (pt) |
| BG (1) | BG61682B1 (pt) |
| BR (1) | BR9206142A (pt) |
| CA (1) | CA2110387A1 (pt) |
| CZ (1) | CZ283478B6 (pt) |
| FI (1) | FI935500A (pt) |
| HU (1) | HU217176B (pt) |
| IE (1) | IE921893A1 (pt) |
| IL (1) | IL102176A (pt) |
| MX (1) | MX9202804A (pt) |
| NO (1) | NO317658B1 (pt) |
| NZ (1) | NZ243114A (pt) |
| RO (1) | RO115415B1 (pt) |
| RU (1) | RU2130782C1 (pt) |
| SK (1) | SK279937B6 (pt) |
| UA (1) | UA27763C2 (pt) |
| WO (1) | WO1992022323A1 (pt) |
| ZA (1) | ZA924276B (pt) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5629162A (en) * | 1991-06-11 | 1997-05-13 | The Center For Blood Research | Method of identifying agents which modulate ICAM-3 binding to LFA-1 |
| WO1999018441A1 (en) * | 1992-01-27 | 1999-04-15 | Icos Corporation | Icam-4 and diagnostic uses thereof |
| US5525487A (en) * | 1992-01-27 | 1996-06-11 | Icos Corporation | DNA encoding I-CAM related protein |
| US5532127A (en) * | 1992-01-27 | 1996-07-02 | Icos Corporation | Assay for 1-CAM related protein expression |
| CA2107097A1 (en) * | 1992-01-27 | 1993-07-28 | Michael W. Gallatin | Icam-related protein |
| US5811517A (en) * | 1992-01-27 | 1998-09-22 | Icos Corporation | ICAM-related protein variants |
| US5989843A (en) * | 1992-01-27 | 1999-11-23 | Icos Corporation | Methods for identifying modulators of protein kinase C phosphorylation of ICAM-related protein |
| US5837822A (en) * | 1992-01-27 | 1998-11-17 | Icos Corporation | Humanized antibodies specific for ICAM related protein |
| US6153395A (en) * | 1992-01-27 | 2000-11-28 | Icos Corporation | ICAM-related protein |
| US6100383A (en) * | 1992-01-27 | 2000-08-08 | Icos Corporation | Fusion proteins comprising ICAM-R polypeptides and immunoglobulin constant regions |
| US5702917A (en) * | 1992-01-27 | 1997-12-30 | Icos Corporation | Polynucleotides encoding human ICAM-4 |
| US6818743B1 (en) | 1992-01-27 | 2004-11-16 | Icos Corporation | I-CAM related protein |
| JPH07506007A (ja) * | 1993-01-22 | 1995-07-06 | イコス コーポレイション | Ｉｃａｍ−関連タンパク質 |
| DK0726942T3 (da) * | 1993-11-02 | 2002-04-15 | Innogenetics Nv | Monoklonale antistoffer mod skumceller og deres farmaceutiske og diagnostiske anvendelse |
| US6884590B1 (en) | 1994-02-11 | 2005-04-26 | Cedars-Sinai Medical Center | Methods of screening for ulcerative colitis and crohn's disease |
| US5681699A (en) * | 1994-02-11 | 1997-10-28 | Cedars-Sinai Medical Center | Methods of diagnosing ulcerative colitis and Crohn's disease |
| US20020081294A1 (en) | 1996-01-23 | 2002-06-27 | Genentech, Inc. | Co-administration of a thrombolytic and an anti-CD18 antibody in stroke |
| US5914112A (en) * | 1996-01-23 | 1999-06-22 | Genentech, Inc. | Anti-CD18 antibodies in stroke |
| JP2001508181A (ja) * | 1997-10-02 | 2001-06-19 | アイコス コーポレイション | Ｉｃａｍ−４及びその診断用途 |
| EP1741428A3 (en) | 1999-08-13 | 2007-05-09 | Biogen Idec MA, Inc. | Cell adhesion inhibitors |
| US8980568B2 (en) | 2001-10-11 | 2015-03-17 | Aviva Biosciences Corporation | Methods and compositions for detecting non-hematopoietic cells from a blood sample |
| US8986944B2 (en) | 2001-10-11 | 2015-03-24 | Aviva Biosciences Corporation | Methods and compositions for separating rare cells from fluid samples |
| US7691591B2 (en) * | 2002-09-20 | 2010-04-06 | Stichting Katholieke Universiteit | Methods of identifying and isolating cells expressing DC-sign |
| US7196112B2 (en) | 2004-07-16 | 2007-03-27 | Biogen Idec Ma Inc. | Cell adhesion inhibitors |
| CN101583722A (zh) | 2006-07-14 | 2009-11-18 | 阿维瓦生物科学股份有限公司 | 从生物学样品检测稀有细胞的方法和组合物 |
| WO2010062960A2 (en) | 2008-11-26 | 2010-06-03 | Cedars-Sinai Medical Center | METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE |
| WO2010075579A2 (en) | 2008-12-24 | 2010-07-01 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (mr-uc) requiring colectomy |
| GB201016864D0 (en) | 2010-10-06 | 2010-11-17 | Univ Aston | Therapeutic methods |
| EP4285988A3 (en) | 2013-03-27 | 2024-03-06 | Cedars-Sinai Medical Center | Treating fibrosis by inhibiting tl1a |
| US10316083B2 (en) | 2013-07-19 | 2019-06-11 | Cedars-Sinai Medical Center | Signature of TL1A (TNFSF15) signaling pathway |
| KR20220153109A (ko) | 2016-03-17 | 2022-11-17 | 세다르스-신나이 메디칼 센터 | Rnaset2를 통한 염증성 장 질환의 진단 방법 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0387668B1 (en) * | 1989-03-09 | 1996-12-11 | Center For Blood Research, Inc. | Intercellular adhesion molecule - 2 and its binding ligands |
-
1992
- 1992-06-11 KR KR1020007000978A patent/KR100333120B1/ko not_active IP Right Cessation
- 1992-06-11 CZ CS932702A patent/CZ283478B6/cs not_active IP Right Cessation
- 1992-06-11 MX MX9202804A patent/MX9202804A/es not_active Application Discontinuation
- 1992-06-11 IL IL10217692A patent/IL102176A/en not_active IP Right Cessation
- 1992-06-11 WO PCT/US1992/004896 patent/WO1992022323A1/en not_active Application Discontinuation
- 1992-06-11 CA CA002110387A patent/CA2110387A1/en not_active Abandoned
- 1992-06-11 UA UA93003881A patent/UA27763C2/uk unknown
- 1992-06-11 KR KR1019930703828A patent/KR100291844B1/ko not_active IP Right Cessation
- 1992-06-11 CN CNB921051263A patent/CN1188528C/zh not_active Expired - Fee Related
- 1992-06-11 RO RO93-01672A patent/RO115415B1/ro unknown
- 1992-06-11 EP EP19920914138 patent/EP0590051A4/xx not_active Ceased
- 1992-06-11 BR BR9206142A patent/BR9206142A/pt not_active Application Discontinuation
- 1992-06-11 ZA ZA924276A patent/ZA924276B/xx unknown
- 1992-06-11 JP JP50099993A patent/JP3288042B2/ja not_active Expired - Fee Related
- 1992-06-11 NZ NZ243114A patent/NZ243114A/xx unknown
- 1992-06-11 SK SK1395-93A patent/SK279937B6/sk unknown
- 1992-06-11 RU RU93058655A patent/RU2130782C1/ru not_active IP Right Cessation
- 1992-07-01 IE IE189392A patent/IE921893A1/en not_active Application Discontinuation
-
1993
- 1993-12-08 FI FI935500A patent/FI935500A/fi unknown
- 1993-12-09 NO NO934491A patent/NO317658B1/no not_active IP Right Cessation
- 1993-12-10 BG BG98287A patent/BG61682B1/bg unknown
- 1993-12-10 HU HU9303529A patent/HU217176B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| RO115415B1 (ro) | 2000-02-28 |
| IE921893A1 (en) | 1992-12-16 |
| UA27763C2 (uk) | 2000-10-16 |
| NZ243114A (en) | 1995-03-28 |
| BR9206142A (pt) | 1994-12-27 |
| KR100333120B1 (ko) | 2002-04-18 |
| NO934491D0 (no) | 1993-12-09 |
| CZ270293A3 (en) | 1994-08-17 |
| ZA924276B (en) | 1993-03-31 |
| CA2110387A1 (en) | 1992-12-23 |
| AU2237692A (en) | 1993-01-12 |
| BG98287A (bg) | 1994-08-30 |
| JP3288042B2 (ja) | 2002-06-04 |
| CZ283478B6 (cs) | 1998-04-15 |
| CN1188528C (zh) | 2005-02-09 |
| AU670243B2 (en) | 1996-07-11 |
| CN1069522A (zh) | 1993-03-03 |
| FI935500A0 (fi) | 1993-12-08 |
| BG61682B1 (bg) | 1998-03-31 |
| SK139593A3 (en) | 1994-10-05 |
| KR100291844B1 (ko) | 2001-09-17 |
| NO934491L (no) | 1994-02-11 |
| EP0590051A4 (en) | 1994-10-12 |
| WO1992022323A1 (en) | 1992-12-23 |
| HUT66617A (en) | 1994-12-28 |
| JPH06509706A (ja) | 1994-11-02 |
| IL102176A0 (en) | 1993-01-14 |
| HU217176B (hu) | 1999-12-28 |
| FI935500A (fi) | 1994-02-09 |
| MX9202804A (es) | 1992-12-01 |
| NO317658B1 (no) | 2004-11-29 |
| RU2130782C1 (ru) | 1999-05-27 |
| HU9303529D0 (en) | 1994-04-28 |
| EP0590051A1 (en) | 1994-04-06 |
| SK279937B6 (sk) | 1999-06-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |