NZ243114A - Icam-3; dna encoding it; antibodies; hybridomas; pharmaceuticals containing icam-3, a derivative or antagonist, anti-icam-3 or fragment; and in vivo and in vitro diagnosis - Google Patents

Icam-3; dna encoding it; antibodies; hybridomas; pharmaceuticals containing icam-3, a derivative or antagonist, anti-icam-3 or fragment; and in vivo and in vitro diagnosis

Info

Publication number
NZ243114A
NZ243114A NZ243114A NZ24311492A NZ243114A NZ 243114 A NZ243114 A NZ 243114A NZ 243114 A NZ243114 A NZ 243114A NZ 24311492 A NZ24311492 A NZ 24311492A NZ 243114 A NZ243114 A NZ 243114A
Authority
NZ
New Zealand
Prior art keywords
icam
hybridomas
antagonist
antibodies
vivo
Prior art date
Application number
NZ243114A
Inventor
Antonin R Defougerolles
Timothy A Springer
Original Assignee
Blood Res Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Blood Res Center filed Critical Blood Res Center
Publication of NZ243114A publication Critical patent/NZ243114A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NZ243114A 1991-06-11 1992-06-11 Icam-3; dna encoding it; antibodies; hybridomas; pharmaceuticals containing icam-3, a derivative or antagonist, anti-icam-3 or fragment; and in vivo and in vitro diagnosis NZ243114A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71287991A 1991-06-11 1991-06-11

Publications (1)

Publication Number Publication Date
NZ243114A true NZ243114A (en) 1995-03-28

Family

ID=24863928

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ243114A NZ243114A (en) 1991-06-11 1992-06-11 Icam-3; dna encoding it; antibodies; hybridomas; pharmaceuticals containing icam-3, a derivative or antagonist, anti-icam-3 or fragment; and in vivo and in vitro diagnosis

Country Status (21)

Country Link
EP (1) EP0590051A4 (en)
JP (1) JP3288042B2 (en)
KR (2) KR100333120B1 (en)
CN (1) CN1188528C (en)
BG (1) BG61682B1 (en)
BR (1) BR9206142A (en)
CA (1) CA2110387A1 (en)
CZ (1) CZ283478B6 (en)
FI (1) FI935500A (en)
HU (1) HU217176B (en)
IE (1) IE921893A1 (en)
IL (1) IL102176A (en)
MX (1) MX9202804A (en)
NO (1) NO317658B1 (en)
NZ (1) NZ243114A (en)
RO (1) RO115415B1 (en)
RU (1) RU2130782C1 (en)
SK (1) SK279937B6 (en)
UA (1) UA27763C2 (en)
WO (1) WO1992022323A1 (en)
ZA (1) ZA924276B (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629162A (en) * 1991-06-11 1997-05-13 The Center For Blood Research Method of identifying agents which modulate ICAM-3 binding to LFA-1
US5837822A (en) * 1992-01-27 1998-11-17 Icos Corporation Humanized antibodies specific for ICAM related protein
US5989843A (en) * 1992-01-27 1999-11-23 Icos Corporation Methods for identifying modulators of protein kinase C phosphorylation of ICAM-related protein
US6818743B1 (en) 1992-01-27 2004-11-16 Icos Corporation I-CAM related protein
US5532127A (en) * 1992-01-27 1996-07-02 Icos Corporation Assay for 1-CAM related protein expression
JP3616090B2 (en) * 1992-01-27 2005-02-02 イコス コーポレイション Intercellular adhesion molecule-related protein
US5880268A (en) * 1992-01-27 1999-03-09 Icos Corporation Modulators of the interaction between ICAM-R and αd /CD18
US5702917A (en) * 1992-01-27 1997-12-30 Icos Corporation Polynucleotides encoding human ICAM-4
US5525487A (en) * 1992-01-27 1996-06-11 Icos Corporation DNA encoding I-CAM related protein
US6100383A (en) * 1992-01-27 2000-08-08 Icos Corporation Fusion proteins comprising ICAM-R polypeptides and immunoglobulin constant regions
WO1999018441A1 (en) * 1992-01-27 1999-04-15 Icos Corporation Icam-4 and diagnostic uses thereof
US6153395A (en) * 1992-01-27 2000-11-28 Icos Corporation ICAM-related protein
CA2132637A1 (en) * 1993-01-22 1994-08-04 Michael W. Gallatin Icam-related protein
PT726942E (en) * 1993-11-02 2002-06-28 Innogenetics Nv MONOCLONAL ANTIBODIES AGAINST FOAM CELLS AND THEIR PHARMACEUTICAL AND DIAGNOSTIC UTILIZATION
US5681699A (en) * 1994-02-11 1997-10-28 Cedars-Sinai Medical Center Methods of diagnosing ulcerative colitis and Crohn's disease
US6884590B1 (en) 1994-02-11 2005-04-26 Cedars-Sinai Medical Center Methods of screening for ulcerative colitis and crohn's disease
US20020081294A1 (en) 1996-01-23 2002-06-27 Genentech, Inc. Co-administration of a thrombolytic and an anti-CD18 antibody in stroke
US5914112A (en) * 1996-01-23 1999-06-22 Genentech, Inc. Anti-CD18 antibodies in stroke
ATE237140T1 (en) * 1997-10-02 2003-04-15 Icos Corp ICAM-4 AND ITS DIAGNOSTIC USES
WO2001012186A1 (en) 1999-08-13 2001-02-22 Biogen, Inc. Cell adhesion inhibitors
US8986944B2 (en) 2001-10-11 2015-03-24 Aviva Biosciences Corporation Methods and compositions for separating rare cells from fluid samples
US8980568B2 (en) 2001-10-11 2015-03-17 Aviva Biosciences Corporation Methods and compositions for detecting non-hematopoietic cells from a blood sample
AU2003278541A1 (en) * 2002-09-20 2004-04-08 Stichting Katholieke Universiteit Method of treating rheumatoid arthritis by interfering with expression of dc-sign by macrophages and diagnosis thereof
US7196112B2 (en) 2004-07-16 2007-03-27 Biogen Idec Ma Inc. Cell adhesion inhibitors
EP2041299A4 (en) 2006-07-14 2010-01-13 Aviva Biosciences Corp Methods and compositions for detecting rare cells from a biological sample
WO2010062960A2 (en) 2008-11-26 2010-06-03 Cedars-Sinai Medical Center METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE
US9580752B2 (en) 2008-12-24 2017-02-28 Cedars-Sinai Medical Center Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy
GB201016864D0 (en) 2010-10-06 2010-11-17 Univ Aston Therapeutic methods
WO2014160883A1 (en) 2013-03-27 2014-10-02 Cedars-Sinai Medical Center Treating fibrosis and inflammation by inhibiting tl1a
US10316083B2 (en) 2013-07-19 2019-06-11 Cedars-Sinai Medical Center Signature of TL1A (TNFSF15) signaling pathway
EP3430172A4 (en) 2016-03-17 2019-08-21 Cedars-Sinai Medical Center DIAGNOSTIC METHOD FOR CHRONIC INFLAMMATORY BOWEL DISEASE THROUGH T2 RNASE

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0387668B1 (en) * 1989-03-09 1996-12-11 Center For Blood Research, Inc. Intercellular adhesion molecule - 2 and its binding ligands

Also Published As

Publication number Publication date
HUT66617A (en) 1994-12-28
HU217176B (en) 1999-12-28
NO317658B1 (en) 2004-11-29
SK279937B6 (en) 1999-06-11
CZ283478B6 (en) 1998-04-15
NO934491L (en) 1994-02-11
IL102176A0 (en) 1993-01-14
NO934491D0 (en) 1993-12-09
CZ270293A3 (en) 1994-08-17
IL102176A (en) 2001-09-13
BG61682B1 (en) 1998-03-31
RO115415B1 (en) 2000-02-28
KR100291844B1 (en) 2001-09-17
ZA924276B (en) 1993-03-31
CA2110387A1 (en) 1992-12-23
EP0590051A1 (en) 1994-04-06
WO1992022323A1 (en) 1992-12-23
KR100333120B1 (en) 2002-04-18
SK139593A3 (en) 1994-10-05
FI935500A (en) 1994-02-09
JP3288042B2 (en) 2002-06-04
MX9202804A (en) 1992-12-01
AU670243B2 (en) 1996-07-11
CN1069522A (en) 1993-03-03
FI935500A0 (en) 1993-12-08
AU2237692A (en) 1993-01-12
EP0590051A4 (en) 1994-10-12
RU2130782C1 (en) 1999-05-27
IE921893A1 (en) 1992-12-16
BG98287A (en) 1994-08-30
BR9206142A (en) 1994-12-27
UA27763C2 (en) 2000-10-16
JPH06509706A (en) 1994-11-02
HU9303529D0 (en) 1994-04-28
CN1188528C (en) 2005-02-09

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