EP0590051A4 - Intercellular adhesion molecule-3 and its binding ligands. - Google Patents

Intercellular adhesion molecule-3 and its binding ligands.

Info

Publication number
EP0590051A4
EP0590051A4 EP19920914138 EP92914138A EP0590051A4 EP 0590051 A4 EP0590051 A4 EP 0590051A4 EP 19920914138 EP19920914138 EP 19920914138 EP 92914138 A EP92914138 A EP 92914138A EP 0590051 A4 EP0590051 A4 EP 0590051A4
Authority
EP
European Patent Office
Prior art keywords
adhesion molecule
intercellular adhesion
binding ligands
ligands
intercellular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP19920914138
Other languages
German (de)
French (fr)
Other versions
EP0590051A1 (en
Inventor
Antonin R Defougerolles
Timothy A Springer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immune Disease Institute Inc
Original Assignee
Immune Disease Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immune Disease Institute Inc filed Critical Immune Disease Institute Inc
Publication of EP0590051A1 publication Critical patent/EP0590051A1/en
Publication of EP0590051A4 publication Critical patent/EP0590051A4/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
EP19920914138 1991-06-11 1992-06-11 Intercellular adhesion molecule-3 and its binding ligands. Ceased EP0590051A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71287991A 1991-06-11 1991-06-11
US712879 1991-06-11
PCT/US1992/004896 WO1992022323A1 (en) 1991-06-11 1992-06-11 Intercellular adhesion molecule-3 and its binding ligands

Publications (2)

Publication Number Publication Date
EP0590051A1 EP0590051A1 (en) 1994-04-06
EP0590051A4 true EP0590051A4 (en) 1994-10-12

Family

ID=24863928

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19920914138 Ceased EP0590051A4 (en) 1991-06-11 1992-06-11 Intercellular adhesion molecule-3 and its binding ligands.

Country Status (21)

Country Link
EP (1) EP0590051A4 (en)
JP (1) JP3288042B2 (en)
KR (2) KR100291844B1 (en)
CN (1) CN1188528C (en)
BG (1) BG61682B1 (en)
BR (1) BR9206142A (en)
CA (1) CA2110387A1 (en)
CZ (1) CZ283478B6 (en)
FI (1) FI935500A (en)
HU (1) HU217176B (en)
IE (1) IE921893A1 (en)
IL (1) IL102176A (en)
MX (1) MX9202804A (en)
NO (1) NO317658B1 (en)
NZ (1) NZ243114A (en)
RO (1) RO115415B1 (en)
RU (1) RU2130782C1 (en)
SK (1) SK279937B6 (en)
UA (1) UA27763C2 (en)
WO (1) WO1992022323A1 (en)
ZA (1) ZA924276B (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891841A (en) * 1991-06-11 1999-04-06 The Center For Blood Research, Inc. Methods of using intercellular adhesion molecule-3 (ICAM-3), antibodies thereto, and soluble fragments thereof
US6818743B1 (en) 1992-01-27 2004-11-16 Icos Corporation I-CAM related protein
JP3616090B2 (en) * 1992-01-27 2005-02-02 イコス コーポレイション Intercellular adhesion molecule-related protein
US5532127A (en) * 1992-01-27 1996-07-02 Icos Corporation Assay for 1-CAM related protein expression
US5837822A (en) * 1992-01-27 1998-11-17 Icos Corporation Humanized antibodies specific for ICAM related protein
US5525487A (en) * 1992-01-27 1996-06-11 Icos Corporation DNA encoding I-CAM related protein
US5989843A (en) * 1992-01-27 1999-11-23 Icos Corporation Methods for identifying modulators of protein kinase C phosphorylation of ICAM-related protein
US5702917A (en) * 1992-01-27 1997-12-30 Icos Corporation Polynucleotides encoding human ICAM-4
WO1999018441A1 (en) * 1992-01-27 1999-04-15 Icos Corporation Icam-4 and diagnostic uses thereof
US6100383A (en) * 1992-01-27 2000-08-08 Icos Corporation Fusion proteins comprising ICAM-R polypeptides and immunoglobulin constant regions
US5811517A (en) * 1992-01-27 1998-09-22 Icos Corporation ICAM-related protein variants
US6153395A (en) * 1992-01-27 2000-11-28 Icos Corporation ICAM-related protein
JPH07506007A (en) * 1993-01-22 1995-07-06 イコス　コーポレイション ICAM-related proteins
US6027922A (en) * 1993-11-02 2000-02-22 Innogenetics N.V. Human foam cells and methods for preparing them, monoclonal antibodies to said foam cells and their pharmaceutical and diagnostic use
US5681699A (en) * 1994-02-11 1997-10-28 Cedars-Sinai Medical Center Methods of diagnosing ulcerative colitis and Crohn's disease
US6884590B1 (en) 1994-02-11 2005-04-26 Cedars-Sinai Medical Center Methods of screening for ulcerative colitis and crohn's disease
US5914112A (en) * 1996-01-23 1999-06-22 Genentech, Inc. Anti-CD18 antibodies in stroke
US20020081294A1 (en) 1996-01-23 2002-06-27 Genentech, Inc. Co-administration of a thrombolytic and an anti-CD18 antibody in stroke
AU735917B2 (en) * 1997-10-02 2001-07-19 Icos Corporation ICAM-4 and diagnostic uses thereof
CA2380817A1 (en) 1999-08-13 2001-02-22 Biogen, Inc. Cell adhesion inhibitors
US8980568B2 (en) 2001-10-11 2015-03-17 Aviva Biosciences Corporation Methods and compositions for detecting non-hematopoietic cells from a blood sample
US8986944B2 (en) 2001-10-11 2015-03-24 Aviva Biosciences Corporation Methods and compositions for separating rare cells from fluid samples
US7691591B2 (en) * 2002-09-20 2010-04-06 Stichting Katholieke Universiteit Methods of identifying and isolating cells expressing DC-sign
US7196112B2 (en) 2004-07-16 2007-03-27 Biogen Idec Ma Inc. Cell adhesion inhibitors
WO2008008515A2 (en) 2006-07-14 2008-01-17 Aviva Biosciences Corporation Methods and compositions for detecting rare cells from a biological sample
US20110229471A1 (en) 2008-11-26 2011-09-22 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease
US9580752B2 (en) 2008-12-24 2017-02-28 Cedars-Sinai Medical Center Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy
GB201016864D0 (en) 2010-10-06 2010-11-17 Univ Aston Therapeutic methods
EP4285988A3 (en) 2013-03-27 2024-03-06 Cedars-Sinai Medical Center Treating fibrosis by inhibiting tl1a
WO2015010108A1 (en) 2013-07-19 2015-01-22 Cedars-Sinai Medical Center Signature of tl1a (tnfsf15) signaling pathway
CN109462996A (en) 2016-03-17 2019-03-12 西达-赛奈医疗中心 The method for diagnosing inflammatory bowel disease by RNASET2

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0387668A1 (en) * 1989-03-09 1990-09-19 Center For Blood Research Laboratories, Inc. Intercellular adhesion molecule - 2 and its binding ligands

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0387668A1 (en) * 1989-03-09 1990-09-19 Center For Blood Research Laboratories, Inc. Intercellular adhesion molecule - 2 and its binding ligands

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
"LEUCOCYTE TYPING IV. WHITE CELL DIFFERENTIATION ANTIGENS (Eds. W. Knapp et al.)", 1989, OXFORD UNIVERSITY PRESS, OXFORD, GB *
A. DE FOUGEROLLES ET AL.: "Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes.", THE JOURNAL OF EXPERIMENTAL MEDICINE, vol. 175, no. 1, 1 January 1992 (1992-01-01), NEW YORK, NY, USA, pages 185 - 190 *
M. JUAN ET AL.: "CDw50 and ICAM-3: Two names for the same molecule.", EUROPEAN JOURNAL OF IMMUNOLOGY, vol. 23, no. 7, July 1993 (1993-07-01), WEINHEIM, GERMANY, pages 1508 - 1512 *
R. VILELLA ET AL.: "Involvement of the CDw50 molecule in allorecognition.", TISSUE ANTIGENS, vol. 36, no. 5, November 1990 (1990-11-01), COPENHAGEN, DENMARK, pages 203 - 210 *
See also references of WO9222323A1 *

Also Published As

Publication number Publication date
CN1188528C (en) 2005-02-09
ZA924276B (en) 1993-03-31
SK279937B6 (en) 1999-06-11
UA27763C2 (en) 2000-10-16
MX9202804A (en) 1992-12-01
NO934491L (en) 1994-02-11
WO1992022323A1 (en) 1992-12-23
BR9206142A (en) 1994-12-27
IL102176A (en) 2001-09-13
EP0590051A1 (en) 1994-04-06
KR100333120B1 (en) 2002-04-18
FI935500A (en) 1994-02-09
JPH06509706A (en) 1994-11-02
RU2130782C1 (en) 1999-05-27
NO317658B1 (en) 2004-11-29
HU9303529D0 (en) 1994-04-28
KR100291844B1 (en) 2001-09-17
BG61682B1 (en) 1998-03-31
AU670243B2 (en) 1996-07-11
CN1069522A (en) 1993-03-03
CA2110387A1 (en) 1992-12-23
HU217176B (en) 1999-12-28
BG98287A (en) 1994-08-30
IL102176A0 (en) 1993-01-14
SK139593A3 (en) 1994-10-05
NZ243114A (en) 1995-03-28
CZ283478B6 (en) 1998-04-15
RO115415B1 (en) 2000-02-28
NO934491D0 (en) 1993-12-09
AU2237692A (en) 1993-01-12
JP3288042B2 (en) 2002-06-04
HUT66617A (en) 1994-12-28
CZ270293A3 (en) 1994-08-17
IE921893A1 (en) 1992-12-16
FI935500A0 (en) 1993-12-08

Similar Documents

Publication Publication Date Title
EP0590051A4 (en) Intercellular adhesion molecule-3 and its binding ligands.
EP0578486A3 (en) Audio Storybook.
GB9105245D0 (en) Binding molecules
AU6319294A (en) Intercellular adhesion molecules, and their binding ligands
GB9016299D0 (en) Binding substances
EP0597842A4 (en) Metal binding proteins.
AU2633288A (en) Intercellular adhesion molecules and their binding ligands
PH31209A (en) Adhesive composition and method.
AU647382B2 (en) Intercellular adhesion molecules and their binding ligands
GB2219249B (en) Cover for books and the like
GB8915738D0 (en) Book binding
ZA937445B (en) Binding element
EP0597499A3 (en) Electronic note book.
GB9027767D0 (en) Binding substances
EP0685347A3 (en) Easy read-out book.
GB2274429B (en) Book binding
GB9310468D0 (en) Sugar complexes
GB2249524B (en) Book binding
IE960275L (en) Intercellular adhesion molecules, and their binding ligands
GB2302062B (en) Album assembly
GB9024503D0 (en) Binding substances
GB9104744D0 (en) Binding substances
GB9110549D0 (en) Binding substances
GB9120252D0 (en) Improvement binding substances
ZA883159B (en) Intercellular adhesion molecules and their binding ligands

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19940111

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE

RHK1 Main classification (correction)

Ipc: C12N 15/12

A4 Supplementary search report drawn up and despatched

Effective date: 19940823

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE

17Q First examination report despatched

Effective date: 19980623

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED

18R Application refused

Effective date: 20040329

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1011619

Country of ref document: HK