HUT66617A - Intercellular adhesion molecule-3 and its binding ligands - Google Patents

Intercellular adhesion molecule-3 and its binding ligands

Info

Publication number
HUT66617A
HUT66617A HU9303529A HU9303529A HUT66617A HU T66617 A HUT66617 A HU T66617A HU 9303529 A HU9303529 A HU 9303529A HU 9303529 A HU9303529 A HU 9303529A HU T66617 A HUT66617 A HU T66617A
Authority
HU
Hungary
Prior art keywords
adhesion molecule
intercellular adhesion
binding ligands
ligands
intercellular
Prior art date
Application number
HU9303529A
Other languages
Hungarian (hu)
Other versions
HU217176B (en
HU9303529D0 (en
Inventor
Timothy Alan Springer
Antonin R Defougerolles
Original Assignee
Blood Res Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Blood Res Center filed Critical Blood Res Center
Publication of HU9303529D0 publication Critical patent/HU9303529D0/en
Publication of HUT66617A publication Critical patent/HUT66617A/en
Publication of HU217176B publication Critical patent/HU217176B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HU9303529A 1991-06-11 1993-12-10 Novel intercellular adhesion molecule and its binding ligands, compositions containing thereof and process for producing thereof HU217176B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71287991A 1991-06-11 1991-06-11

Publications (3)

Publication Number Publication Date
HU9303529D0 HU9303529D0 (en) 1994-04-28
HUT66617A true HUT66617A (en) 1994-12-28
HU217176B HU217176B (en) 1999-12-28

Family

ID=24863928

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9303529A HU217176B (en) 1991-06-11 1993-12-10 Novel intercellular adhesion molecule and its binding ligands, compositions containing thereof and process for producing thereof

Country Status (21)

Country Link
EP (1) EP0590051A4 (en)
JP (1) JP3288042B2 (en)
KR (2) KR100291844B1 (en)
CN (1) CN1188528C (en)
BG (1) BG61682B1 (en)
BR (1) BR9206142A (en)
CA (1) CA2110387A1 (en)
CZ (1) CZ283478B6 (en)
FI (1) FI935500A (en)
HU (1) HU217176B (en)
IE (1) IE921893A1 (en)
IL (1) IL102176A (en)
MX (1) MX9202804A (en)
NO (1) NO317658B1 (en)
NZ (1) NZ243114A (en)
RO (1) RO115415B1 (en)
RU (1) RU2130782C1 (en)
SK (1) SK279937B6 (en)
UA (1) UA27763C2 (en)
WO (1) WO1992022323A1 (en)
ZA (1) ZA924276B (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891841A (en) * 1991-06-11 1999-04-06 The Center For Blood Research, Inc. Methods of using intercellular adhesion molecule-3 (ICAM-3), antibodies thereto, and soluble fragments thereof
US5532127A (en) * 1992-01-27 1996-07-02 Icos Corporation Assay for 1-CAM related protein expression
US5989843A (en) * 1992-01-27 1999-11-23 Icos Corporation Methods for identifying modulators of protein kinase C phosphorylation of ICAM-related protein
US6818743B1 (en) 1992-01-27 2004-11-16 Icos Corporation I-CAM related protein
US5837822A (en) * 1992-01-27 1998-11-17 Icos Corporation Humanized antibodies specific for ICAM related protein
US6100383A (en) * 1992-01-27 2000-08-08 Icos Corporation Fusion proteins comprising ICAM-R polypeptides and immunoglobulin constant regions
US6153395A (en) * 1992-01-27 2000-11-28 Icos Corporation ICAM-related protein
US5525487A (en) * 1992-01-27 1996-06-11 Icos Corporation DNA encoding I-CAM related protein
WO1999018441A1 (en) * 1992-01-27 1999-04-15 Icos Corporation Icam-4 and diagnostic uses thereof
US5702917A (en) * 1992-01-27 1997-12-30 Icos Corporation Polynucleotides encoding human ICAM-4
US5773218A (en) * 1992-01-27 1998-06-30 Icos Corporation Method to identify compounds which modulate ICAM-related protein interactions
JP3616090B2 (en) * 1992-01-27 2005-02-02 イコス コーポレイション Intercellular adhesion molecule-related protein
WO1994017100A1 (en) * 1993-01-22 1994-08-04 Icos Corporation Icam-related protein
US6027922A (en) * 1993-11-02 2000-02-22 Innogenetics N.V. Human foam cells and methods for preparing them, monoclonal antibodies to said foam cells and their pharmaceutical and diagnostic use
US5681699A (en) * 1994-02-11 1997-10-28 Cedars-Sinai Medical Center Methods of diagnosing ulcerative colitis and Crohn's disease
US6884590B1 (en) 1994-02-11 2005-04-26 Cedars-Sinai Medical Center Methods of screening for ulcerative colitis and crohn's disease
US5914112A (en) * 1996-01-23 1999-06-22 Genentech, Inc. Anti-CD18 antibodies in stroke
US20020081294A1 (en) 1996-01-23 2002-06-27 Genentech, Inc. Co-administration of a thrombolytic and an anti-CD18 antibody in stroke
RU2208230C2 (en) * 1997-10-02 2003-07-10 Айкос Корпорейшн Icam-4 and method for applying it in diagnosing diseases
KR100720907B1 (en) 1999-08-13 2007-05-25 바이오겐 아이덱 엠에이 인코포레이티드 Cell adhesion inhibitors
US8986944B2 (en) 2001-10-11 2015-03-24 Aviva Biosciences Corporation Methods and compositions for separating rare cells from fluid samples
US8980568B2 (en) 2001-10-11 2015-03-17 Aviva Biosciences Corporation Methods and compositions for detecting non-hematopoietic cells from a blood sample
US7691591B2 (en) * 2002-09-20 2010-04-06 Stichting Katholieke Universiteit Methods of identifying and isolating cells expressing DC-sign
US7196112B2 (en) 2004-07-16 2007-03-27 Biogen Idec Ma Inc. Cell adhesion inhibitors
CN101583722A (en) 2006-07-14 2009-11-18 阿维瓦生物科学股份有限公司 Methods and compositions for detecting rare cells from a biological sample
US20110229471A1 (en) 2008-11-26 2011-09-22 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease
US9580752B2 (en) 2008-12-24 2017-02-28 Cedars-Sinai Medical Center Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy
GB201016864D0 (en) 2010-10-06 2010-11-17 Univ Aston Therapeutic methods
AU2014241162A1 (en) 2013-03-27 2015-10-22 Cedars-Sinai Medical Center Mitigation and reversal of fibrosis and inflammation by inhibition of TL1A function and related signaling pathways
US10316083B2 (en) 2013-07-19 2019-06-11 Cedars-Sinai Medical Center Signature of TL1A (TNFSF15) signaling pathway
CN109462996A (en) 2016-03-17 2019-03-12 西达-赛奈医疗中心 The method for diagnosing inflammatory bowel disease by RNASET2

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0387668B1 (en) * 1989-03-09 1996-12-11 Center For Blood Research, Inc. Intercellular adhesion molecule - 2 and its binding ligands

Also Published As

Publication number Publication date
EP0590051A1 (en) 1994-04-06
SK139593A3 (en) 1994-10-05
RO115415B1 (en) 2000-02-28
NO317658B1 (en) 2004-11-29
AU2237692A (en) 1993-01-12
MX9202804A (en) 1992-12-01
IL102176A0 (en) 1993-01-14
KR100291844B1 (en) 2001-09-17
CN1188528C (en) 2005-02-09
CA2110387A1 (en) 1992-12-23
SK279937B6 (en) 1999-06-11
EP0590051A4 (en) 1994-10-12
BG61682B1 (en) 1998-03-31
AU670243B2 (en) 1996-07-11
CN1069522A (en) 1993-03-03
NZ243114A (en) 1995-03-28
WO1992022323A1 (en) 1992-12-23
IL102176A (en) 2001-09-13
IE921893A1 (en) 1992-12-16
RU2130782C1 (en) 1999-05-27
FI935500A (en) 1994-02-09
BG98287A (en) 1994-08-30
NO934491D0 (en) 1993-12-09
HU217176B (en) 1999-12-28
JP3288042B2 (en) 2002-06-04
NO934491L (en) 1994-02-11
CZ270293A3 (en) 1994-08-17
ZA924276B (en) 1993-03-31
JPH06509706A (en) 1994-11-02
CZ283478B6 (en) 1998-04-15
FI935500A0 (en) 1993-12-08
HU9303529D0 (en) 1994-04-28
KR100333120B1 (en) 2002-04-18
BR9206142A (en) 1994-12-27
UA27763C2 (en) 2000-10-16

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Legal Events

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HMM4 Cancellation of final prot. due to non-payment of fee