HUT56120A - Intercellular adhezive molekules and theyr binding ligands - Google Patents

Intercellular adhezive molekules and theyr binding ligands

Info

Publication number
HUT56120A
HUT56120A HU896074A HU607489A HUT56120A HU T56120 A HUT56120 A HU T56120A HU 896074 A HU896074 A HU 896074A HU 607489 A HU607489 A HU 607489A HU T56120 A HUT56120 A HU T56120A
Authority
HU
Hungary
Prior art keywords
molekules
adhezive
theyr
intercellular
binding ligands
Prior art date
Application number
HU896074A
Other languages
Hungarian (hu)
Other versions
HU218904B (en
HU896074D0 (en
Inventor
Timothy Alan Springer
Robert Rothlein
Steven Dean Marlin
Michael Loran Dustin
Original Assignee
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc
Publication of HU896074D0 publication Critical patent/HU896074D0/en
Publication of HUT56120A publication Critical patent/HUT56120A/en
Publication of HU218904B publication Critical patent/HU218904B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HU074/89A 1988-09-28 1989-09-28 Method for producing recombinant dna coding icam-1, cells expressing icam-1, or pharmaceutical compositions for diagnosing diseases and treating inflammations derived from the answer of specific defense system HU218904B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25044688A 1988-09-28 1988-09-28
US37388289A 1989-06-30 1989-06-30

Publications (3)

Publication Number Publication Date
HU896074D0 HU896074D0 (en) 1990-11-28
HUT56120A true HUT56120A (en) 1991-07-29
HU218904B HU218904B (en) 2000-12-28

Family

ID=26940882

Family Applications (1)

Application Number Title Priority Date Filing Date
HU074/89A HU218904B (en) 1988-09-28 1989-09-28 Method for producing recombinant dna coding icam-1, cells expressing icam-1, or pharmaceutical compositions for diagnosing diseases and treating inflammations derived from the answer of specific defense system

Country Status (7)

Country Link
JP (1) JP2976381B2 (en)
KR (1) KR900701846A (en)
AU (2) AU4412889A (en)
DK (1) DK175362B1 (en)
FI (2) FI102181B1 (en)
HU (1) HU218904B (en)
WO (1) WO1990003400A1 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA896668B (en) * 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
US6143298A (en) * 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
ES2097748T3 (en) * 1989-03-16 1997-04-16 Blood Res Center USE OF FUNCTIONAL DERIVATIVES OF THE ICAM-1 INTERCELLULAR ADHESION MOLECULA IN ANTIVIRIC THERAPY.
WO1991018010A1 (en) * 1990-05-15 1991-11-28 Swinburne Limited Inhibition of viral infection using intercellular adhesion molecule-1-like peptides and/or analogues thereof
WO1991018011A1 (en) * 1990-05-15 1991-11-28 Swinburne Limited Inhibition of cell adhesion using intercellular adhesion molecule-1-like peptides and/or analogues thereof
DK162890D0 (en) * 1990-07-06 1990-07-06 Novo Nordisk As POLYPEPTIDE
US5686582A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
US5686581A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric form of human rhinovirus receptor protein
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US5283058A (en) 1990-08-30 1994-02-01 The General Hospital Corporation Methods for inhibiting rejection of transplanted tissue
CA2056143A1 (en) * 1990-11-28 1992-05-29 Michael S. Diamond The mac-1 binding site of icam-1
US5932214A (en) 1994-08-11 1999-08-03 Biogen, Inc. Treatment for inflammatory bowel disease with VLA-4 blockers
PT644768E (en) * 1992-06-11 2002-03-28 Scripps Research Inst METHODS AND COMPOSITIONS FOR INHIBITING INFLAMMATION MEDIATED BY ENDOTHELIAL CELLS AND FIBRINOGEN
US5599790A (en) 1992-06-11 1997-02-04 The Scripps Research Institute Fibrinogen γ chain polypeptide and compositions thereof
EP0670734A4 (en) * 1992-10-09 1998-01-14 Blood Res Center A subpopulation of mac-1 (cd11b/cd18) molecules which mediate neutrophil adhesion to icam-1 and fibrinogen.
DE4335273A1 (en) * 1993-10-15 1995-04-20 Univ Ludwigs Albert Peptides for tumor therapy
WO1995028170A1 (en) * 1994-04-19 1995-10-26 The University Of Kansas Icam-1/lfa-1 short-chain peptides and method of using same
WO1997000956A1 (en) * 1995-06-20 1997-01-09 Trustees Of Boston University Hypoxia-responsive adhesion molecules, specific antibodies, and their uses
AU7338500A (en) * 1999-09-01 2001-03-26 Boehringer Ingelheim Pharmaceuticals, Inc. Methods and compositions for treating autoimmune disease
CA2544678C (en) 2003-11-05 2013-12-31 Sunesis Pharmaceuticals, Inc. Modulators of cellular adhesion
SI2444079T1 (en) 2005-05-17 2017-05-31 Sarcode Bioscience Inc. Compositions and Methods for Treatment of Eye Disorders
EP2209371B1 (en) 2007-10-19 2017-01-04 SARcode Bioscience Inc. Compositions and methods for treatment of diabetic retinopathy
JP5554993B2 (en) * 2007-11-15 2014-07-23 中外製薬株式会社 Monoclonal antibody binding to nexelekto and use thereof
US8080562B2 (en) 2008-04-15 2011-12-20 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
WO2011050175A1 (en) 2009-10-21 2011-04-28 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
US9085553B2 (en) 2012-07-25 2015-07-21 SARcode Bioscience, Inc. LFA-1 inhibitor and methods of preparation and polymorph thereof
WO2019105864A1 (en) 2017-11-30 2019-06-06 F. Hoffmann-La Roche Ag B-cell cultivation method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2080044T3 (en) * 1987-05-04 1996-02-01 Dana Farber Cancer Inst Inc INTERCELLULAR ADHESION MOLECULES AND THEIR FIXATION LINKS.
EP0314863B1 (en) * 1987-11-02 1994-12-07 Baylor College Of Medicine Use of ICAM-1 or its functional derivatives for the treatment of non-specific inflammation

Also Published As

Publication number Publication date
FI981097A (en) 1998-05-18
JP2976381B2 (en) 1999-11-10
AU4412889A (en) 1990-04-18
AU6319294A (en) 1994-08-25
JPH03501861A (en) 1991-04-25
DK175362B1 (en) 2004-09-13
FI102181B (en) 1998-10-30
FI107451B (en) 2001-08-15
DK128990A (en) 1990-07-26
HU218904B (en) 2000-12-28
WO1990003400A1 (en) 1990-04-05
FI981097A0 (en) 1989-09-28
AU679506B2 (en) 1997-07-03
FI102181B1 (en) 1998-10-30
DK128990D0 (en) 1990-05-25
FI902490A0 (en) 1990-05-21
HU896074D0 (en) 1990-11-28
KR900701846A (en) 1990-12-04

Similar Documents

Publication Publication Date Title
HUT56120A (en) Intercellular adhezive molekules and theyr binding ligands
IL102176A0 (en) Intercellular adhesion molecule-3 and its binding ligands
GB2214363B (en) Multi-piece connector and receptacle therefor
EP0343364A3 (en) Positioning and press-sealing means
EP0368661A3 (en) Microwave filter
GB2221003B (en) Clamp assemblies
GB2216029B (en) Filter assembly and filter manifold
EP0330500A3 (en) Magneto-optic garnet
AU2633288A (en) Intercellular adhesion molecules and their binding ligands
AU647382B2 (en) Intercellular adhesion molecules and their binding ligands
GB2219249B (en) Cover for books and the like
ZA893875B (en) Electronicaly variable space-to-sales
GB8816401D0 (en) Book binding
EP0342957A3 (en) Binding system
ZA883159B (en) Intercellular adhesion molecules and their binding ligands
GB2219766B (en) Binder spine assembly
ZA897335B (en) Intercellular adhesion molecules and their binding ligands
ZA901835B (en) Intercellular adhesion molecule-2 and its binding ligands
GB2200105B (en) Improvements in fertiliser
IE960275L (en) Intercellular adhesion molecules, and their binding ligands
GB8816465D0 (en) Binding of basic refactories
GB8913342D0 (en) Binder
GB8804422D0 (en) Complexes
GB8820274D0 (en) Dextran complexes
GB8812037D0 (en) Variable geometry manifolds