BR9206142A - Molécula de adesão intercelular-3 e seus ligantes de aglutinação - Google Patents

Molécula de adesão intercelular-3 e seus ligantes de aglutinação

Info

Publication number
BR9206142A
BR9206142A BR9206142A BR9206142A BR9206142A BR 9206142 A BR9206142 A BR 9206142A BR 9206142 A BR9206142 A BR 9206142A BR 9206142 A BR9206142 A BR 9206142A BR 9206142 A BR9206142 A BR 9206142A
Authority
BR
Brazil
Prior art keywords
agglutination
ligands
adhesion molecule
intercellular adhesion
intercellular
Prior art date
Application number
BR9206142A
Other languages
English (en)
Inventor
Antonin R Defougerolles
Timothy A Springer
Original Assignee
Blood Res Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Blood Res Center filed Critical Blood Res Center
Publication of BR9206142A publication Critical patent/BR9206142A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
BR9206142A 1991-06-11 1992-06-11 Molécula de adesão intercelular-3 e seus ligantes de aglutinação BR9206142A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71287991A 1991-06-11 1991-06-11
PCT/US1992/004896 WO1992022323A1 (en) 1991-06-11 1992-06-11 Intercellular adhesion molecule-3 and its binding ligands

Publications (1)

Publication Number Publication Date
BR9206142A true BR9206142A (pt) 1994-12-27

Family

ID=24863928

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9206142A BR9206142A (pt) 1991-06-11 1992-06-11 Molécula de adesão intercelular-3 e seus ligantes de aglutinação

Country Status (21)

Country Link
EP (1) EP0590051A4 (pt)
JP (1) JP3288042B2 (pt)
KR (2) KR100333120B1 (pt)
CN (1) CN1188528C (pt)
BG (1) BG61682B1 (pt)
BR (1) BR9206142A (pt)
CA (1) CA2110387A1 (pt)
CZ (1) CZ283478B6 (pt)
FI (1) FI935500A (pt)
HU (1) HU217176B (pt)
IE (1) IE921893A1 (pt)
IL (1) IL102176A (pt)
MX (1) MX9202804A (pt)
NO (1) NO317658B1 (pt)
NZ (1) NZ243114A (pt)
RO (1) RO115415B1 (pt)
RU (1) RU2130782C1 (pt)
SK (1) SK279937B6 (pt)
UA (1) UA27763C2 (pt)
WO (1) WO1992022323A1 (pt)
ZA (1) ZA924276B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629162A (en) * 1991-06-11 1997-05-13 The Center For Blood Research Method of identifying agents which modulate ICAM-3 binding to LFA-1
US5837822A (en) * 1992-01-27 1998-11-17 Icos Corporation Humanized antibodies specific for ICAM related protein
US6100383A (en) * 1992-01-27 2000-08-08 Icos Corporation Fusion proteins comprising ICAM-R polypeptides and immunoglobulin constant regions
US6818743B1 (en) 1992-01-27 2004-11-16 Icos Corporation I-CAM related protein
US5525487A (en) * 1992-01-27 1996-06-11 Icos Corporation DNA encoding I-CAM related protein
US5702917A (en) * 1992-01-27 1997-12-30 Icos Corporation Polynucleotides encoding human ICAM-4
WO1999018441A1 (en) * 1992-01-27 1999-04-15 Icos Corporation Icam-4 and diagnostic uses thereof
US6153395A (en) * 1992-01-27 2000-11-28 Icos Corporation ICAM-related protein
US5532127A (en) * 1992-01-27 1996-07-02 Icos Corporation Assay for 1-CAM related protein expression
US5989843A (en) * 1992-01-27 1999-11-23 Icos Corporation Methods for identifying modulators of protein kinase C phosphorylation of ICAM-related protein
US5869262A (en) * 1992-01-27 1999-02-09 Icos Corporation Method for monitoring an inflammatory disease state by detecting circulating ICAM-R
CA2107097A1 (en) * 1992-01-27 1993-07-28 Michael W. Gallatin Icam-related protein
CA2132637A1 (en) * 1993-01-22 1994-08-04 Michael W. Gallatin Icam-related protein
ATE211167T1 (de) * 1993-11-02 2002-01-15 Innogenetics Nv Monoklonale antikörper gegen schaumzellen und ihre pharmazeutische und diagnostische anwendung
US6884590B1 (en) 1994-02-11 2005-04-26 Cedars-Sinai Medical Center Methods of screening for ulcerative colitis and crohn's disease
US5681699A (en) * 1994-02-11 1997-10-28 Cedars-Sinai Medical Center Methods of diagnosing ulcerative colitis and Crohn's disease
US5914112A (en) * 1996-01-23 1999-06-22 Genentech, Inc. Anti-CD18 antibodies in stroke
US20020081294A1 (en) 1996-01-23 2002-06-27 Genentech, Inc. Co-administration of a thrombolytic and an anti-CD18 antibody in stroke
CN1132014C (zh) * 1997-10-02 2003-12-24 艾科斯有限公司 Icam－4抗体的应用
PT1265606E (pt) 1999-08-13 2007-01-31 Biogen Idec Inc Inibidores da adesão celular
US8986944B2 (en) 2001-10-11 2015-03-24 Aviva Biosciences Corporation Methods and compositions for separating rare cells from fluid samples
US8980568B2 (en) 2001-10-11 2015-03-17 Aviva Biosciences Corporation Methods and compositions for detecting non-hematopoietic cells from a blood sample
WO2004026909A2 (en) * 2002-09-20 2004-04-01 Stichting Katholieke Universiteit Method of treating rheumatoid arthritis by interfering with expression of dc-sign by macrophages and diagnosis thereof
US7196112B2 (en) 2004-07-16 2007-03-27 Biogen Idec Ma Inc. Cell adhesion inhibitors
WO2008008515A2 (en) 2006-07-14 2008-01-17 Aviva Biosciences Corporation Methods and compositions for detecting rare cells from a biological sample
WO2010062960A2 (en) 2008-11-26 2010-06-03 Cedars-Sinai Medical Center METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE
US9580752B2 (en) 2008-12-24 2017-02-28 Cedars-Sinai Medical Center Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy
GB201016864D0 (en) 2010-10-06 2010-11-17 Univ Aston Therapeutic methods
EP4285988A3 (en) 2013-03-27 2024-03-06 Cedars-Sinai Medical Center Treating fibrosis by inhibiting tl1a
EP4105236A1 (en) 2013-07-19 2022-12-21 Cedars-Sinai Medical Center Anti-tl1a (tnfsf15) antibody for treatment of inflammatory bowel disease
KR20220153109A (ko) 2016-03-17 2022-11-17 세다르스-신나이 메디칼 센터 Rnaset2를 통한 염증성 장 질환의 진단 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2011633C (en) * 1989-03-09 2007-05-15 Timothy A. Springer Intercellular adhesion molecule - 2 and its binding ligands

Also Published As

Publication number Publication date
IE921893A1 (en) 1992-12-16
SK139593A3 (en) 1994-10-05
SK279937B6 (sk) 1999-06-11
NZ243114A (en) 1995-03-28
KR100333120B1 (ko) 2002-04-18
AU2237692A (en) 1993-01-12
AU670243B2 (en) 1996-07-11
CN1069522A (zh) 1993-03-03
JP3288042B2 (ja) 2002-06-04
WO1992022323A1 (en) 1992-12-23
CZ270293A3 (en) 1994-08-17
BG98287A (bg) 1994-08-30
FI935500A (fi) 1994-02-09
IL102176A (en) 2001-09-13
MX9202804A (es) 1992-12-01
EP0590051A1 (en) 1994-04-06
EP0590051A4 (en) 1994-10-12
ZA924276B (en) 1993-03-31
CZ283478B6 (cs) 1998-04-15
BG61682B1 (bg) 1998-03-31
CA2110387A1 (en) 1992-12-23
IL102176A0 (en) 1993-01-14
HUT66617A (en) 1994-12-28
RO115415B1 (ro) 2000-02-28
HU217176B (hu) 1999-12-28
KR100291844B1 (ko) 2001-09-17
NO934491D0 (no) 1993-12-09
NO317658B1 (no) 2004-11-29
CN1188528C (zh) 2005-02-09
NO934491L (no) 1994-02-11
HU9303529D0 (en) 1994-04-28
UA27763C2 (uk) 2000-10-16
FI935500A0 (fi) 1993-12-08
JPH06509706A (ja) 1994-11-02
RU2130782C1 (ru) 1999-05-27

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Legal Events

Date Code Title Description
EE Request for examination
FB36 Technical and formal requirements: requirement - article 36 of industrial property law
FC Decision: refusal
CKFC Appeal: appeal against refusal
B15K Others concerning applications: alteration of classification

Ipc: C12Q 1/6881 (2018.01), C07K 14/705 (2006.0