IL101444A - Pharmaceutical compositions containing tetronic and thiotetronic acid derivatives and some novel compounds of this type - Google Patents

Pharmaceutical compositions containing tetronic and thiotetronic acid derivatives and some novel compounds of this type

Info

Publication number
IL101444A
IL101444A IL10144492A IL10144492A IL101444A IL 101444 A IL101444 A IL 101444A IL 10144492 A IL10144492 A IL 10144492A IL 10144492 A IL10144492 A IL 10144492A IL 101444 A IL101444 A IL 101444A
Authority
IL
Israel
Prior art keywords
type
pharmaceutical compositions
compositions containing
acid derivatives
novel compounds
Prior art date
Application number
IL10144492A
Other languages
English (en)
Other versions
IL101444A0 (en
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of IL101444A0 publication Critical patent/IL101444A0/xx
Publication of IL101444A publication Critical patent/IL101444A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/32—Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
IL10144492A 1991-04-12 1992-04-01 Pharmaceutical compositions containing tetronic and thiotetronic acid derivatives and some novel compounds of this type IL101444A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/685,265 US5242945A (en) 1991-04-12 1991-04-12 Tetronic and thiotetronic acid derivatives as phospholipase a2 inhibitors

Publications (2)

Publication Number Publication Date
IL101444A0 IL101444A0 (en) 1992-12-30
IL101444A true IL101444A (en) 1997-02-18

Family

ID=24751448

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10144492A IL101444A (en) 1991-04-12 1992-04-01 Pharmaceutical compositions containing tetronic and thiotetronic acid derivatives and some novel compounds of this type

Country Status (14)

Country Link
US (1) US5242945A (fr)
EP (1) EP0508690A1 (fr)
JP (1) JPH0597839A (fr)
KR (1) KR920019770A (fr)
AU (1) AU649120B2 (fr)
CA (1) CA2065228A1 (fr)
FI (1) FI921596A (fr)
HU (1) HUT61738A (fr)
IE (1) IE920880A1 (fr)
IL (1) IL101444A (fr)
MX (1) MX9201657A (fr)
NZ (1) NZ242301A (fr)
TW (1) TW206219B (fr)
ZA (1) ZA922181B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9302419A (es) * 1992-04-28 1994-03-31 American Home Prod Derivados de acido tetronico, tiotetronico y tetramico.
US5508302A (en) * 1994-09-28 1996-04-16 American Home Products Corporation Phospholipase A2 inhibitors
US5428058A (en) * 1994-09-28 1995-06-27 American Home Products Corporation Phospholipase A2 inhibitors
AU721881B2 (en) * 1996-03-27 2000-07-13 Toray Industries, Inc. Ketone derivatives and medicinal use thereof
CA2222471A1 (fr) * 1996-03-27 1997-10-02 Toray Industries, Inc. Derives de cetone et utilisation medicale connexe
GB2321455A (en) * 1997-01-24 1998-07-29 Norsk Hydro As Lipophilic derivatives of biologically active compounds
ATE305235T1 (de) * 1998-12-22 2005-10-15 Unilever Nv Kosmetische verwendung von petroselinsäure
DK1406895T3 (da) * 2001-06-13 2008-12-01 Magnachem Int Lab Inc Lactonformuleringer og fremgangsmåde til anvendelse deraf
US8188145B2 (en) * 2002-06-12 2012-05-29 Magnachem International Laboratories, Inc. Synthetic lactone formulations and method of use
MXPA05004794A (es) * 2002-11-05 2005-08-19 Magnachem Int Lab Inc Formulaciones de lactonas y metodos de uso.
KR20110128785A (ko) * 2008-10-24 2011-11-30 매그나켐 인터내셔널 레버러토리즈 아이엔씨 Ｒａｄ9와 선택적으로 상호작용하는 화합물들의 스크리닝방법
CN117802156A (zh) * 2024-02-29 2024-04-02 云南师范大学 硼酸转运蛋白基因在转基因植株筛选中的应用及筛选方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1276061A (en) * 1970-01-14 1972-06-01 Ici Ltd Tetronic acid derivatives, process for the manufacture thereof, and compositions containing such compounds
JPS4969659A (fr) * 1972-10-31 1974-07-05
JPS511633A (ja) * 1974-06-25 1976-01-08 Toray Industries Noengeiyosatsukinzai
US4874782A (en) * 1985-07-01 1989-10-17 Eli Lilly And Company Furanone derivatives
JPS6219582A (ja) * 1985-07-19 1987-01-28 Agency Of Ind Science & Technol γ−チオブチロラクトン誘導体の製造方法
US5045564A (en) * 1988-12-07 1991-09-03 Allergan, Inc. Anti-inflammatory 2-furanones

Also Published As

Publication number Publication date
HU9201238D0 (en) 1992-07-28
JPH0597839A (ja) 1993-04-20
HUT61738A (en) 1993-03-01
EP0508690A1 (fr) 1992-10-14
FI921596A (fi) 1992-10-13
US5242945A (en) 1993-09-07
IL101444A0 (en) 1992-12-30
AU649120B2 (en) 1994-05-12
MX9201657A (es) 1992-10-01
ZA922181B (en) 1993-09-27
KR920019770A (ko) 1992-11-19
FI921596A0 (fi) 1992-04-10
AU1482692A (en) 1992-10-15
CA2065228A1 (fr) 1992-10-13
IE920880A1 (en) 1992-10-21
TW206219B (fr) 1993-05-21
NZ242301A (en) 1997-03-24

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
HCA Change of name of proprietor(s) after amalgamation
MM9K Patent not in force due to non-payment of renewal fees