IL100811A - פפטידים סנטטים לנטילת רעל של בקטריות רעלן פנים ולמניעת וטיפול " בהלם אלחי" - Google Patents

פפטידים סנטטים לנטילת רעל של בקטריות רעלן פנים ולמניעת וטיפול " בהלם אלחי"

Info

Publication number
IL100811A
IL100811A IL10081192A IL10081192A IL100811A IL 100811 A IL100811 A IL 100811A IL 10081192 A IL10081192 A IL 10081192A IL 10081192 A IL10081192 A IL 10081192A IL 100811 A IL100811 A IL 100811A
Authority
IL
Israel
Prior art keywords
lys
peptide
phe
leu
cys
Prior art date
Application number
IL10081192A
Other languages
English (en)
Other versions
IL100811A0 (en
Original Assignee
Porro Massimo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Porro Massimo filed Critical Porro Massimo
Publication of IL100811A0 publication Critical patent/IL100811A0/xx
Publication of IL100811A publication Critical patent/IL100811A/he

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0815Tripeptides with the first amino acid being basic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL10081192A 1991-02-11 1992-01-30 פפטידים סנטטים לנטילת רעל של בקטריות רעלן פנים ולמניעת וטיפול " בהלם אלחי" IL100811A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65874491A 1991-02-11 1991-02-11
US07/819,893 US5371186A (en) 1991-02-11 1992-01-16 Synthetic peptides for detoxification of bacterial endotoxins and for the prevention and treatment of septic shock

Publications (2)

Publication Number Publication Date
IL100811A0 IL100811A0 (en) 1992-09-06
IL100811A true IL100811A (he) 1999-07-14

Family

ID=25229363

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10081192A IL100811A (he) 1991-02-11 1992-01-30 פפטידים סנטטים לנטילת רעל של בקטריות רעלן פנים ולמניעת וטיפול " בהלם אלחי"

Country Status (16)

Country Link
US (2) US5371186A (he)
EP (1) EP0623144B1 (he)
JP (1) JPH07505606A (he)
AT (1) ATE212355T1 (he)
AU (1) AU665945B2 (he)
CA (1) CA2123576A1 (he)
DE (1) DE69232378T2 (he)
DK (1) DK0623144T3 (he)
ES (1) ES2172506T3 (he)
FI (1) FI943396A0 (he)
HU (1) HUT69707A (he)
IE (1) IE920437A1 (he)
IL (1) IL100811A (he)
NZ (1) NZ241446A (he)
TW (1) TW215441B (he)
WO (1) WO1993014115A1 (he)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5652211A (en) * 1991-02-11 1997-07-29 Biosynth S.R.L. Peptides for neutralizing the toxicity of Lipid A
US5371186A (en) * 1991-02-11 1994-12-06 Biosynth S.R.L. Synthetic peptides for detoxification of bacterial endotoxins and for the prevention and treatment of septic shock
US5733872A (en) * 1993-03-12 1998-03-31 Xoma Corporation Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof
US5610075A (en) * 1995-01-17 1997-03-11 Stahl-Rees; Marianne Competitive electrochemiluminescence assays for endotoxins using a ruthenium label
US5834430A (en) * 1995-05-31 1998-11-10 Biosynth S.R.L. Potentiation of antibiotics
WO1998035665A1 (fr) * 1997-02-14 1998-08-20 Ajinomoto Co., Inc. Antagonistes des endotoxines
JP2001512140A (ja) 1997-07-31 2001-08-21 アカデミック・ジーケヌース・ビーアイジェイ・デ・ユニバーシティト・ヴァン・アムステルダム 敗血症治療のための抗菌性及びエンドトキシン不活性化能を有する新規な合成ペプチド
WO1999011281A1 (en) * 1997-09-05 1999-03-11 Dana-Farber Cancer Institute The use of agents which bind g proteins for treating septic shock
US6194562B1 (en) 1998-04-22 2001-02-27 Promega Corporation Endotoxin reduction in nucleic acid purification
US7078224B1 (en) * 1999-05-14 2006-07-18 Promega Corporation Cell concentration and lysate clearance using paramagnetic particles
US6951652B2 (en) * 1998-07-29 2005-10-04 Biosynth S.R.L. Vaccine for prevention of gram-negative bacterial infections and endotoxin related diseases
US6116663A (en) * 1998-10-19 2000-09-12 Cercueils Vic Royal, Inc. Casket Lock
DE10117043A1 (de) * 2001-04-05 2002-11-07 Gerhard Puetz Verfahren zur Eliminierung von potentiell toxischen und/oder schädlichen Stoffen
WO2003094961A1 (en) * 2002-05-09 2003-11-20 Massimo Porro Improved polysaccharide and glycoconjugate vaccines_____________
WO2004015099A2 (en) 2002-08-02 2004-02-19 Glaxosmithkline Biologicals Sa Vaccine composition comprising lipooligosaccharide with reduced phase variability
WO2004052394A1 (en) * 2002-12-06 2004-06-24 Biosynth S.R.L. Broad-spectrum lps based vaccines of unencapsulated strains of haemophilus influenzae and other pathogenic species of gram-negative bacteria
GB2408263A (en) * 2003-11-14 2005-05-25 Pacgen Biopharmaceuticals Inc Antimicrobial peptides with reduced hemolysis and methods of their use.
JP5173194B2 (ja) 2003-12-23 2013-03-27 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン
US7507718B2 (en) 2005-04-11 2009-03-24 Sanofi Pasteur Polymyxin B analogs for LPS detoxification
EP1712559A1 (en) * 2005-04-11 2006-10-18 Sanofi Pasteur Polymyxin B analogs for LPS detoxification
CA2603850A1 (en) * 2005-04-11 2006-10-19 Sanofi Pasteur Polymyxin b analogs for lps detoxification
US8030034B2 (en) 2005-12-09 2011-10-04 Promega Corporation Nucleic acid purification with a binding matrix
JP5275983B2 (ja) 2006-06-12 2013-08-28 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン
ES2350430B1 (es) * 2009-05-28 2011-11-18 Fundacion De La Comunidad Valenciana Centro De Investigacion Principe Felipe,95%. Conjugado polimerico para el tratamiento de infecciones bacterianas
TWI548746B (zh) * 2009-08-06 2016-09-11 英特威特國際股份有限公司 防備豬胸膜肺炎之疫苗及製備該疫苗之方法
US8039613B2 (en) 2009-08-28 2011-10-18 Promega Corporation Methods of purifying a nucleic acid and formulation and kit for use in performing such methods
US8222397B2 (en) 2009-08-28 2012-07-17 Promega Corporation Methods of optimal purification of nucleic acids and kit for use in performing such methods
JP2013521770A (ja) 2010-03-10 2013-06-13 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン組成物
KR101858840B1 (ko) * 2016-01-15 2018-05-16 단국대학교 천안캠퍼스 산학협력단 집먼지진드기 유래 알레르겐에 의한 과민반응 면역조절제

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340012C (en) * 1987-08-17 1998-08-25 Trustees Of Leland Stanford Jr. University Peptide determinant associated with immunity
US5593966A (en) * 1989-03-31 1997-01-14 The United States Of America As Represented By The Department Of Health And Human Services Peptide derivatives of cytochrome b558 and their use as medicaments
US5358932A (en) * 1989-12-29 1994-10-25 Zymogenetics, Inc. Hybrid protein C
US5371186A (en) * 1991-02-11 1994-12-06 Biosynth S.R.L. Synthetic peptides for detoxification of bacterial endotoxins and for the prevention and treatment of septic shock
ZA92943B (en) * 1991-02-11 1992-11-25 Porro Massimo Synthetic peptides for detoxification of bacterial endotoxins and for the prevention and treatment of septic shock

Also Published As

Publication number Publication date
AU1691492A (en) 1993-08-03
IL100811A0 (en) 1992-09-06
HUT69707A (en) 1995-09-28
ES2172506T3 (es) 2002-10-01
WO1993014115A1 (en) 1993-07-22
FI943396A (fi) 1994-07-15
TW215441B (he) 1993-11-01
DK0623144T3 (da) 2002-05-13
US5589459A (en) 1996-12-31
EP0623144A1 (en) 1994-11-09
EP0623144B1 (en) 2002-01-23
DE69232378D1 (de) 2002-03-14
FI943396A0 (fi) 1994-07-15
AU665945B2 (en) 1996-01-25
ATE212355T1 (de) 2002-02-15
CA2123576A1 (en) 1993-07-22
DE69232378T2 (de) 2002-10-31
US5371186A (en) 1994-12-06
NZ241446A (en) 1995-03-28
JPH07505606A (ja) 1995-06-22
HU9401970D0 (en) 1994-09-28
IE920437A1 (en) 1992-08-12

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