IL100424A - Salinomycin biomass nuclei with free flow and dust, with undisturbed bionic acquisition of the active substance, and a process for their preparation - Google Patents
Salinomycin biomass nuclei with free flow and dust, with undisturbed bionic acquisition of the active substance, and a process for their preparationInfo
- Publication number
- IL100424A IL100424A IL10042491A IL10042491A IL100424A IL 100424 A IL100424 A IL 100424A IL 10042491 A IL10042491 A IL 10042491A IL 10042491 A IL10042491 A IL 10042491A IL 100424 A IL100424 A IL 100424A
- Authority
- IL
- Israel
- Prior art keywords
- salinomycin
- weight
- culture broth
- free
- granules
- Prior art date
Links
- KQXDHUJYNAXLNZ-XQSDOZFQSA-N Salinomycin Chemical compound O1[C@@H]([C@@H](CC)C(O)=O)CC[C@H](C)[C@@H]1[C@@H](C)[C@H](O)[C@H](C)C(=O)[C@H](CC)[C@@H]1[C@@H](C)C[C@@H](C)[C@@]2(C=C[C@@H](O)[C@@]3(O[C@@](C)(CC3)[C@@H]3O[C@@H](C)[C@@](O)(CC)CC3)O2)O1 KQXDHUJYNAXLNZ-XQSDOZFQSA-N 0.000 title claims abstract description 31
- 239000004189 Salinomycin Substances 0.000 title claims abstract description 31
- 229960001548 salinomycin Drugs 0.000 title claims abstract description 31
- 235000019378 salinomycin Nutrition 0.000 title claims abstract description 31
- 239000008187 granular material Substances 0.000 title claims abstract description 23
- 238000000034 method Methods 0.000 title claims abstract description 18
- 239000002028 Biomass Substances 0.000 title claims abstract description 13
- 238000004519 manufacturing process Methods 0.000 title claims description 5
- 239000013543 active substance Substances 0.000 title abstract description 9
- 238000001694 spray drying Methods 0.000 claims abstract description 12
- 229920003086 cellulose ether Polymers 0.000 claims abstract description 8
- 239000001692 EU approved anti-caking agent Substances 0.000 claims abstract description 4
- 239000003795 chemical substances by application Substances 0.000 claims description 16
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 14
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 8
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 8
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 8
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 8
- 239000002245 particle Substances 0.000 claims description 6
- 239000000377 silicon dioxide Substances 0.000 claims description 6
- 239000007921 spray Substances 0.000 claims description 6
- 238000000855 fermentation Methods 0.000 claims description 5
- 230000004151 fermentation Effects 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 4
- 238000001228 spectrum Methods 0.000 claims description 2
- 239000003925 fat Substances 0.000 claims 1
- 239000000428 dust Substances 0.000 abstract description 10
- 235000010633 broth Nutrition 0.000 description 32
- 238000001035 drying Methods 0.000 description 9
- 229940105329 carboxymethylcellulose Drugs 0.000 description 7
- 239000000843 powder Substances 0.000 description 6
- 238000005299 abrasion Methods 0.000 description 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L calcium carbonate Substances [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000008188 pellet Substances 0.000 description 2
- 229910002012 Aerosil® Inorganic materials 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- 239000005909 Kieselgur Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- 239000007900 aqueous suspension Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 235000010216 calcium carbonate Nutrition 0.000 description 1
- 239000012876 carrier material Substances 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000008094 contradictory effect Effects 0.000 description 1
- 230000003292 diminished effect Effects 0.000 description 1
- 238000010410 dusting Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 238000003801 milling Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- JTJMJGYZQZDUJJ-UHFFFAOYSA-N phencyclidine Chemical class C1CCCCN1C1(C=2C=CC=CC=2)CCCCC1 JTJMJGYZQZDUJJ-UHFFFAOYSA-N 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B66—HOISTING; LIFTING; HAULING
- B66B—ELEVATORS; ESCALATORS OR MOVING WALKWAYS
- B66B9/00—Kinds or types of lifts in, or associated with, buildings or other structures
- B66B9/06—Kinds or types of lifts in, or associated with, buildings or other structures inclined, e.g. serving blast furnaces
- B66B9/08—Kinds or types of lifts in, or associated with, buildings or other structures inclined, e.g. serving blast furnaces associated with stairways, e.g. for transporting disabled persons
- B66B9/0807—Driving mechanisms
- B66B9/0815—Rack and pinion, friction rollers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/005—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor after treatment of microbial biomass not covered by C12N1/02 - C12N1/08
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S426/00—Food or edible material: processes, compositions, and products
- Y10S426/807—Poultry or ruminant feed
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/804—Single cell protein
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Sustainable Development (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Mechanical Engineering (AREA)
- Automation & Control Theory (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Transportation (AREA)
- Public Health (AREA)
- Structural Engineering (AREA)
- Fodder In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Fertilizers (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4041190 | 1990-12-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL100424A0 IL100424A0 (en) | 1992-09-06 |
| IL100424A true IL100424A (en) | 1996-10-31 |
Family
ID=6421041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10042491A IL100424A (en) | 1990-12-21 | 1991-12-19 | Salinomycin biomass nuclei with free flow and dust, with undisturbed bionic acquisition of the active substance, and a process for their preparation |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5529911A (cs) |
| EP (1) | EP0493761B1 (cs) |
| JP (1) | JP3170332B2 (cs) |
| AU (1) | AU648369B2 (cs) |
| BG (1) | BG60973B1 (cs) |
| CA (1) | CA2057760C (cs) |
| CZ (1) | CZ281400B6 (cs) |
| DE (1) | DE59107845D1 (cs) |
| DK (1) | DK0493761T3 (cs) |
| ES (1) | ES2088451T3 (cs) |
| HR (1) | HRP940764B1 (cs) |
| HU (1) | HU215095B (cs) |
| IL (1) | IL100424A (cs) |
| MX (1) | MX9102752A (cs) |
| PL (1) | PL292903A1 (cs) |
| RU (1) | RU2168302C2 (cs) |
| SK (1) | SK279482B6 (cs) |
| YU (1) | YU48437B (cs) |
| ZA (1) | ZA919984B (cs) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110983900A (zh) * | 2019-11-25 | 2020-04-10 | 江苏柏威建设有限公司 | 一种室外地坪改造降低扬尘的方法 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6924133B1 (en) * | 1999-10-01 | 2005-08-02 | Novozymes A/S | Spray dried enzyme product |
| JP4790957B2 (ja) * | 1999-10-01 | 2011-10-12 | ノボザイムス アクティーゼルスカブ | 酵素粒質物 |
| SK283167B6 (sk) * | 2000-05-04 | 2003-03-04 | Biotika, A. S. | Spôsob izolácie salinomycínu z vyfermentovanej pôdy |
| DE10247036A1 (de) * | 2002-10-09 | 2004-04-22 | Basf Ag | Vitamin B6 und/oder deren Salze enthaltende Futtermitteladditive und Verfahren zu deren Herstellung |
| US20150267210A1 (en) | 2012-10-16 | 2015-09-24 | Genebridges Gmbh | Electrocompetent cells and preparation thereof |
| KR20140061071A (ko) * | 2012-11-13 | 2014-05-21 | 삼성정밀화학 주식회사 | 셀룰로오스 에테르를 함유한 발효유 조성물 및 그의 제조 방법 |
| KR102626965B1 (ko) * | 2015-08-28 | 2024-01-18 | 앨가힐스 (에이에이치) 리미티드 | 미세조류로부터 푸코크산틴 및/또는 다당류를 생산하기 위한 개선된 방법 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4233405A (en) * | 1979-10-10 | 1980-11-11 | Rohm And Haas Company | Process for spray drying enzymes |
| DE3005313C2 (de) * | 1980-02-13 | 1986-05-28 | SEMIKRON Gesellschaft für Gleichrichterbau u. Elektronik mbH, 8500 Nürnberg | Halbleiteranordnung |
| DE3005642A1 (de) * | 1980-02-15 | 1981-08-20 | Hoechst Ag, 6000 Frankfurt | Feststoff der salinomycin-kulturbruehe und verfahren zu seiner gewinnung |
| US4824829A (en) * | 1984-08-15 | 1989-04-25 | American Cyanamid Company | Non-dusting antibiotic, anticoccidial premix compositions and a process for their manufacture |
| DK435587D0 (da) * | 1987-08-21 | 1987-08-21 | Novo Industri As | Fremgangsmaade til fremstilling af et enzymholdigt granulat |
-
1991
- 1991-12-16 BG BG95636A patent/BG60973B1/bg unknown
- 1991-12-16 YU YU194391A patent/YU48437B/sh unknown
- 1991-12-19 IL IL10042491A patent/IL100424A/en not_active IP Right Cessation
- 1991-12-19 ZA ZA919984A patent/ZA919984B/xx unknown
- 1991-12-20 CA CA002057760A patent/CA2057760C/en not_active Expired - Fee Related
- 1991-12-20 PL PL29290391A patent/PL292903A1/xx unknown
- 1991-12-20 MX MX9102752A patent/MX9102752A/es not_active IP Right Cessation
- 1991-12-20 JP JP33743391A patent/JP3170332B2/ja not_active Expired - Lifetime
- 1991-12-20 CZ CS913991A patent/CZ281400B6/cs not_active IP Right Cessation
- 1991-12-20 AU AU89899/91A patent/AU648369B2/en not_active Ceased
- 1991-12-20 EP EP91121930A patent/EP0493761B1/de not_active Expired - Lifetime
- 1991-12-20 RU SU5010689/13A patent/RU2168302C2/ru not_active IP Right Cessation
- 1991-12-20 DE DE59107845T patent/DE59107845D1/de not_active Expired - Fee Related
- 1991-12-20 SK SK3991-91A patent/SK279482B6/sk unknown
- 1991-12-20 ES ES91121930T patent/ES2088451T3/es not_active Expired - Lifetime
- 1991-12-20 HU HU914077A patent/HU215095B/hu not_active IP Right Cessation
- 1991-12-20 DK DK91121930.1T patent/DK0493761T3/da active
-
1994
- 1994-08-19 US US08/293,163 patent/US5529911A/en not_active Expired - Lifetime
- 1994-10-25 HR HR940764A patent/HRP940764B1/xx not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110983900A (zh) * | 2019-11-25 | 2020-04-10 | 江苏柏威建设有限公司 | 一种室外地坪改造降低扬尘的方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2168302C2 (ru) | 2001-06-10 |
| CZ281400B6 (cs) | 1996-09-11 |
| HU914077D0 (en) | 1992-03-30 |
| AU8989991A (en) | 1992-06-25 |
| PL292903A1 (en) | 1992-08-10 |
| JPH0530987A (ja) | 1993-02-09 |
| AU648369B2 (en) | 1994-04-21 |
| HRP940764A2 (en) | 1997-04-30 |
| HU215095B (hu) | 1998-09-28 |
| EP0493761A1 (de) | 1992-07-08 |
| BG95636A (bg) | 1993-12-24 |
| YU194391A (sh) | 1995-03-27 |
| HUT59963A (en) | 1992-07-28 |
| JP3170332B2 (ja) | 2001-05-28 |
| ES2088451T3 (es) | 1996-08-16 |
| YU48437B (sh) | 1998-07-10 |
| SK279482B6 (sk) | 1998-12-02 |
| CA2057760C (en) | 2004-03-30 |
| DK0493761T3 (da) | 1996-09-16 |
| DE59107845D1 (de) | 1996-06-27 |
| MX9102752A (es) | 1992-06-01 |
| CA2057760A1 (en) | 1992-06-22 |
| BG60973B1 (bg) | 1996-07-31 |
| IL100424A0 (en) | 1992-09-06 |
| US5529911A (en) | 1996-06-25 |
| CS399191A3 (en) | 1992-08-12 |
| HRP940764B1 (en) | 2000-10-31 |
| EP0493761B1 (de) | 1996-05-22 |
| ZA919984B (en) | 1992-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| HP | Change in proprietorship | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |