IE65618B1 - Alkylated polyethylenimine derivatives process for their preparation their use as pharmaceuticals and pharmaceutical preparations - Google Patents
Alkylated polyethylenimine derivatives process for their preparation their use as pharmaceuticals and pharmaceutical preparationsInfo
- Publication number
- IE65618B1 IE65618B1 IE21490A IE21490A IE65618B1 IE 65618 B1 IE65618 B1 IE 65618B1 IE 21490 A IE21490 A IE 21490A IE 21490 A IE21490 A IE 21490A IE 65618 B1 IE65618 B1 IE 65618B1
- Authority
- IE
- Ireland
- Prior art keywords
- crosslinked
- bile acid
- polyethylenimine
- alkylated
- pharmaceutical preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/02—Polyamines
- C08G73/0206—Polyalkylene(poly)amines
- C08G73/0213—Preparatory process
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3481—Organic compounds containing oxygen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3535—Organic compounds containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nutrition Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Professional, Industrial, Or Sporting Protective Garments (AREA)
- Liquid Developers In Electrophotography (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3901527A DE3901527A1 (de) | 1989-01-20 | 1989-01-20 | Alkylierte polyethyleniminderivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel sowie pharmazeutische praeparate |
Publications (2)
Publication Number | Publication Date |
---|---|
IE900214L IE900214L (en) | 1990-07-20 |
IE65618B1 true IE65618B1 (en) | 1995-11-01 |
Family
ID=6372414
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE21490A IE65618B1 (en) | 1989-01-20 | 1990-01-19 | Alkylated polyethylenimine derivatives process for their preparation their use as pharmaceuticals and pharmaceutical preparations |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0379161B1 (de) |
JP (1) | JPH02232229A (de) |
AT (1) | ATE111931T1 (de) |
AU (1) | AU624215B2 (de) |
CA (1) | CA2008114A1 (de) |
DE (2) | DE3901527A1 (de) |
DK (1) | DK0379161T3 (de) |
ES (1) | ES2063173T3 (de) |
FI (1) | FI900297A0 (de) |
IE (1) | IE65618B1 (de) |
IL (1) | IL93098A0 (de) |
NO (1) | NO900279L (de) |
NZ (1) | NZ232149A (de) |
PT (1) | PT92880B (de) |
ZA (1) | ZA90394B (de) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0534304A1 (de) * | 1991-09-21 | 1993-03-31 | Hoechst Aktiengesellschaft | Cycloalkylierte Polyethyleniminderivate und ihre Verwendung als Hypolipidämika |
EP0534316A1 (de) * | 1991-09-21 | 1993-03-31 | Hoechst Aktiengesellschaft | Verwendung von alkylierten Polyethyleniminderivaten zur Anreicherung von Gallensäuren |
DE69326231T2 (de) * | 1992-01-14 | 1999-12-30 | Hisamitsu Pharmaceutical Co., Inc. | Cholesterinspiegelsenkendes mittel |
ES2080549T3 (es) * | 1992-03-28 | 1996-02-01 | Hoechst Ag | Medicamentos a base de derivados de polihidroximetileno, procedimiento para su preparacion y empleo. |
DK0580078T3 (da) * | 1992-07-22 | 1998-05-25 | Hoechst Ag | Polyvinylamin-derivater med hydrofyle centrer,fremgangsmåde til deres fremstilling samt anvendelse af forbindelserne som lægemidler, bærere af aktive stoffer og næringsmiddelhjælpestof. |
EP0580079B1 (de) * | 1992-07-22 | 1996-12-11 | Hoechst Aktiengesellschaft | Vernetzte, stickstoffhaltige Vinylcopolymere, Verfahren zu ihrer Herstellung sowie die Verwendung dieser Verbindungen |
US5667775A (en) | 1993-08-11 | 1997-09-16 | Geltex Pharmaceuticals, Inc. | Phosphate-binding polymers for oral administration |
US5496545A (en) * | 1993-08-11 | 1996-03-05 | Geltex Pharmaceuticals, Inc. | Phosphate-binding polymers for oral administration |
TW474813B (en) | 1994-06-10 | 2002-02-01 | Geltex Pharma Inc | Alkylated composition for removing bile salts from a patient |
US6268392B1 (en) | 1994-09-13 | 2001-07-31 | G. D. Searle & Co. | Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors |
US6642268B2 (en) | 1994-09-13 | 2003-11-04 | G.D. Searle & Co. | Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors |
US5994391A (en) * | 1994-09-13 | 1999-11-30 | G.D. Searle And Company | Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake |
US6262277B1 (en) | 1994-09-13 | 2001-07-17 | G.D. Searle And Company | Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake |
US6107494A (en) * | 1994-09-13 | 2000-08-22 | G.D. Searle And Company | Substituted 5-aryl-benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake |
US20030069601A1 (en) | 1998-12-15 | 2003-04-10 | Closys Corporation | Clotting cascade initiating apparatus and methods of use |
CA2356422C (en) | 1998-12-23 | 2008-09-16 | G.D. Searle Llc | Combinations of ileal bile acid transport inhibitors and cholesteryl ester transfer protein inhibitors for cardiovascular indications |
EP1340510A1 (de) | 1998-12-23 | 2003-09-03 | G.D. Searle LLC. | Kombinationen von Cholesteryl-Ester-Transfer-Protein-Inhibitoren und Gallensäure-Sequestriermittel für kardiovaskuläre Indikationen |
AU776953B2 (en) | 1998-12-23 | 2004-09-30 | G.D. Searle Llc | Combinations of ileal bile acid transport inhibitors and bile acid sequestring agents for cardiovascular indications |
CA2356607A1 (en) | 1998-12-23 | 2000-07-06 | G.D. Searle Llc | Combinations of ileal bile acid transport inhibitors and fibric acid derivatives for cardiovascular indications |
WO2000038721A1 (en) | 1998-12-23 | 2000-07-06 | G.D. Searle Llc | Combinations of cholesteryl ester transfer protein inhibitors and nicotinic acid derivatives for cardiovascular indications |
PL348503A1 (en) | 1998-12-23 | 2002-05-20 | Searle Llc | Combinations of cholesteryl ester transfer protein inhibitors and fibric acid derivatives for cardiovascular indications |
AU2157400A (en) | 1998-12-23 | 2000-07-31 | G.D. Searle & Co. | Combinations of cholesteryl ester transfer protein inhibitors and hmg coa reductase inhibitors for cardiovascular indications |
US6733780B1 (en) | 1999-10-19 | 2004-05-11 | Genzyme Corporation | Direct compression polymer tablet core |
JP2003528830A (ja) | 2000-03-10 | 2003-09-30 | ファルマシア・コーポレーション | テトラヒドロベンゾチエピン類の製造方法 |
DE10065710A1 (de) * | 2000-12-29 | 2002-07-04 | Bayer Ag | Arzneimittel enthaltend ein Polyamin als Wirksubstanz |
WO2003040127A1 (en) | 2001-11-02 | 2003-05-15 | G.D. Searle Llc | Novel mono- and di-fluorinated benzothiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (asbt) and taurocholate uptake |
JP2005521653A (ja) | 2002-01-17 | 2005-07-21 | ファルマシア コーポレイション | 先端ナトリウム同時依存性胆汁酸輸送(asbt)およびタウロコール酸塩取込みの阻害剤としての新規アルキル/アリールヒドロキシまたはケトチエピン化合物 |
GB0221942D0 (en) * | 2002-09-20 | 2002-10-30 | Univ Strathclyde | Drug delivery |
US7985418B2 (en) | 2004-11-01 | 2011-07-26 | Genzyme Corporation | Aliphatic amine polymer salts for tableting |
US8986669B2 (en) | 2005-09-02 | 2015-03-24 | Genzyme Corporation | Method for removing phosphate and polymer used therefore |
CN103027896B (zh) | 2005-09-15 | 2016-01-20 | 基酶有限公司 | 胺聚合物的小袋制剂 |
US10231721B2 (en) | 2010-06-24 | 2019-03-19 | St. Croix Surgical Systems, Llc | Failsafe percutaneous wound barrier |
MA41202A (fr) | 2014-12-18 | 2017-10-24 | Genzyme Corp | Copolymères polydiallymine réticulé pour le traitement du diabète de type 2 |
CN110907543A (zh) * | 2019-09-29 | 2020-03-24 | 重庆健能医药开发有限公司 | 一种铝碳酸镁咀嚼片胆汁酸吸附的实验方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3251778A (en) * | 1960-08-04 | 1966-05-17 | Petrolite Corp | Process of preventing scale |
US3332841A (en) * | 1961-10-04 | 1967-07-25 | Lilly Co Eli | Method of treating hyperacidity |
JPS5548221A (en) * | 1978-10-04 | 1980-04-05 | Nippon Oil Co Ltd | Preparation of polyhexamethyleneimine |
JPS5566513A (en) * | 1978-11-14 | 1980-05-20 | Ono Pharmaceut Co Ltd | Drug for arteriosclerosis comprising high polymer compound as active constituent |
JPS62243620A (ja) * | 1986-04-17 | 1987-10-24 | Asahi Chem Ind Co Ltd | 表面変性全芳香族ポリアミド成形物及びその製造方法 |
-
1989
- 1989-01-20 DE DE3901527A patent/DE3901527A1/de not_active Withdrawn
-
1990
- 1990-01-17 EP EP90100887A patent/EP0379161B1/de not_active Expired - Lifetime
- 1990-01-17 DE DE59007178T patent/DE59007178D1/de not_active Expired - Fee Related
- 1990-01-17 AT AT90100887T patent/ATE111931T1/de not_active IP Right Cessation
- 1990-01-17 ES ES90100887T patent/ES2063173T3/es not_active Expired - Lifetime
- 1990-01-17 PT PT92880A patent/PT92880B/pt not_active IP Right Cessation
- 1990-01-17 DK DK90100887.0T patent/DK0379161T3/da active
- 1990-01-18 IL IL93098A patent/IL93098A0/xx not_active IP Right Cessation
- 1990-01-18 FI FI900297A patent/FI900297A0/fi not_active Application Discontinuation
- 1990-01-18 NZ NZ232149A patent/NZ232149A/en unknown
- 1990-01-19 CA CA002008114A patent/CA2008114A1/en not_active Abandoned
- 1990-01-19 AU AU48618/90A patent/AU624215B2/en not_active Ceased
- 1990-01-19 IE IE21490A patent/IE65618B1/en not_active IP Right Cessation
- 1990-01-19 NO NO90900279A patent/NO900279L/no unknown
- 1990-01-19 JP JP2008569A patent/JPH02232229A/ja active Pending
- 1990-01-19 ZA ZA90394A patent/ZA90394B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
IL93098A0 (en) | 1990-11-05 |
DK0379161T3 (da) | 1995-01-16 |
NZ232149A (en) | 1991-12-23 |
PT92880A (pt) | 1990-07-31 |
EP0379161A2 (de) | 1990-07-25 |
PT92880B (pt) | 1995-12-29 |
NO900279L (no) | 1990-07-23 |
AU4861890A (en) | 1990-07-26 |
JPH02232229A (ja) | 1990-09-14 |
IE900214L (en) | 1990-07-20 |
FI900297A0 (fi) | 1990-01-18 |
ATE111931T1 (de) | 1994-10-15 |
NO900279D0 (no) | 1990-01-19 |
DE3901527A1 (de) | 1990-07-26 |
DE59007178D1 (de) | 1994-10-27 |
EP0379161B1 (de) | 1994-09-21 |
ZA90394B (en) | 1991-04-24 |
ES2063173T3 (es) | 1995-01-01 |
CA2008114A1 (en) | 1990-07-20 |
EP0379161A3 (de) | 1991-07-31 |
AU624215B2 (en) | 1992-06-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Patent lapsed |