IE51411B1 - 11alpha-amino-androstanes - Google Patents

11alpha-amino-androstanes

Info

Publication number
IE51411B1
IE51411B1 IE1604/81A IE160481A IE51411B1 IE 51411 B1 IE51411 B1 IE 51411B1 IE 1604/81 A IE1604/81 A IE 1604/81A IE 160481 A IE160481 A IE 160481A IE 51411 B1 IE51411 B1 IE 51411B1
Authority
IE
Ireland
Prior art keywords
group
compound
lla
hydroxy
compounds
Prior art date
Application number
IE1604/81A
Other languages
English (en)
Other versions
IE811604L (en
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IE811604L publication Critical patent/IE811604L/xx
Publication of IE51411B1 publication Critical patent/IE51411B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008Expansion of ring D by one atom, e.g. D homo steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0011Unsubstituted amino radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IE1604/81A 1980-07-16 1981-07-15 11alpha-amino-androstanes IE51411B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8023295 1980-07-16
GB8039383 1980-12-09
GB8106487 1981-03-02
GB8116413 1981-05-29

Publications (2)

Publication Number Publication Date
IE811604L IE811604L (en) 1982-01-16
IE51411B1 true IE51411B1 (en) 1986-12-24

Family

ID=27449191

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1604/81A IE51411B1 (en) 1980-07-16 1981-07-15 11alpha-amino-androstanes

Country Status (11)

Country Link
US (1) US4353898A (Sortimente)
AU (1) AU541732B2 (Sortimente)
CA (1) CA1173433A (Sortimente)
DE (1) DE3127972A1 (Sortimente)
DK (1) DK315181A (Sortimente)
FR (1) FR2487359A1 (Sortimente)
GB (1) GB2080308B (Sortimente)
IE (1) IE51411B1 (Sortimente)
IT (1) IT1171389B (Sortimente)
NZ (1) NZ197725A (Sortimente)
SE (1) SE8104393L (Sortimente)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57158800A (en) * 1981-03-02 1982-09-30 Glaxo Group Ltd 11 alpha-amino-3 beta-hydroxyandrostane compound
ZA823783B (en) * 1981-05-29 1983-03-30 Glaxo Group Ltd 11 alpha-amino-androstanes
DE3260539D1 (en) * 1981-05-29 1984-09-13 Glaxo Group Ltd 11-alpha-amino-androstanes
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2982775A (en) * 1957-05-06 1961-05-02 Schering Corp 11-oximino-, amino- and acylaminosteroids
GB887815A (en) * 1957-05-06 1962-01-24 Scherico Ltd Steroids
NL122816C (Sortimente) * 1958-08-07
US3064013A (en) * 1959-01-12 1962-11-13 Upjohn Co Steroidal 11-oximes and a process for their production
GB878069A (en) * 1959-01-12 1961-09-27 Upjohn Co Improvements in or relating to steroids and the manufacture thereof
US3256331A (en) * 1959-07-28 1966-06-14 Merck & Co Inc Process for preparing oximes, hydrazones and semicarbazones of unreactive carbonyl compounds
US3215713A (en) * 1960-04-04 1965-11-02 Schering Corp Steroid nitrite esters
US3558673A (en) * 1966-10-29 1971-01-26 Ormonoterapia Richter Spa 10beta-amino-19-nor-pregnanes and method for the preparation thereof
US3943124A (en) * 1970-12-17 1976-03-09 Gordon Hanley Phillipps Chemical compounds
GB1439605A (en) * 1972-07-14 1976-06-16 Akzo Nv 2beta-hydroxy-3-alpha-amino-steroids and derivatives thereof and the processes for their preparation
GB1581234A (en) * 1976-04-05 1980-12-10 Glaxo Operations Ltd 11a - amino - 3a - hydroxysteroids

Also Published As

Publication number Publication date
AU7287781A (en) 1982-01-21
US4353898A (en) 1982-10-12
SE8104393L (sv) 1982-01-17
DK315181A (da) 1982-01-17
IT8148901A0 (it) 1981-07-15
NZ197725A (en) 1984-11-09
IT8148901A1 (it) 1983-01-15
CA1173433A (en) 1984-08-28
GB2080308B (en) 1984-03-28
IT1171389B (it) 1987-06-10
GB2080308A (en) 1982-02-03
DE3127972A1 (de) 1982-04-15
AU541732B2 (en) 1985-01-17
IE811604L (en) 1982-01-16
FR2487359B1 (Sortimente) 1984-07-13
FR2487359A1 (fr) 1982-01-29

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