IE44614B1 - 4-amino-6,7-dimethoxy-2-(4-(heterocyclylcarbonyl) piperazin-1-yl) quinazolines - Google Patents

4-amino-6,7-dimethoxy-2-(4-(heterocyclylcarbonyl) piperazin-1-yl) quinazolines

Info

Publication number
IE44614B1
IE44614B1 IE338/77A IE33877A IE44614B1 IE 44614 B1 IE44614 B1 IE 44614B1 IE 338/77 A IE338/77 A IE 338/77A IE 33877 A IE33877 A IE 33877A IE 44614 B1 IE44614 B1 IE 44614B1
Authority
IE
Ireland
Prior art keywords
compound
amino
quinazoline
dimethoxy
formula
Prior art date
Application number
IE338/77A
Other languages
English (en)
Other versions
IE44614L (en
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/658,961 external-priority patent/US4001237A/en
Priority claimed from US05/658,979 external-priority patent/US4001238A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IE44614L publication Critical patent/IE44614L/xx
Publication of IE44614B1 publication Critical patent/IE44614B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IE338/77A 1976-02-18 1977-02-17 4-amino-6,7-dimethoxy-2-(4-(heterocyclylcarbonyl) piperazin-1-yl) quinazolines IE44614B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/658,961 US4001237A (en) 1976-02-18 1976-02-18 Oxazole, isoxazole, thiazole and isothiazole amides
US05/658,979 US4001238A (en) 1976-02-18 1976-02-18 1,3,4-oxadiazole amides

Publications (2)

Publication Number Publication Date
IE44614L IE44614L (en) 1977-08-18
IE44614B1 true IE44614B1 (en) 1982-01-27

Family

ID=27097727

Family Applications (1)

Application Number Title Priority Date Filing Date
IE338/77A IE44614B1 (en) 1976-02-18 1977-02-17 4-amino-6,7-dimethoxy-2-(4-(heterocyclylcarbonyl) piperazin-1-yl) quinazolines

Country Status (16)

Country Link
JP (1) JPS584716B2 (enrdf_load_stackoverflow)
CA (1) CA1081228A (enrdf_load_stackoverflow)
CH (1) CH635838A5 (enrdf_load_stackoverflow)
CY (1) CY1122A (enrdf_load_stackoverflow)
DE (1) DE2707067A1 (enrdf_load_stackoverflow)
DK (1) DK65177A (enrdf_load_stackoverflow)
FI (2) FI770485A7 (enrdf_load_stackoverflow)
FR (1) FR2348924A1 (enrdf_load_stackoverflow)
GB (1) GB1533529A (enrdf_load_stackoverflow)
IE (1) IE44614B1 (enrdf_load_stackoverflow)
KE (1) KE3155A (enrdf_load_stackoverflow)
LU (1) LU76802A1 (enrdf_load_stackoverflow)
MY (1) MY8200110A (enrdf_load_stackoverflow)
NL (1) NL7701753A (enrdf_load_stackoverflow)
SE (1) SE7701732L (enrdf_load_stackoverflow)
YU (4) YU45477A (enrdf_load_stackoverflow)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5791987A (en) * 1980-11-26 1982-06-08 Sankyo Co Ltd Aminoquinazoline derivative and its preparation
US5932538A (en) * 1996-02-02 1999-08-03 Nitromed, Inc. Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses
US5994294A (en) * 1996-02-02 1999-11-30 Nitromed, Inc. Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses
UA79286C2 (en) * 2002-06-29 2007-06-11 Zentaris Gmbh Arylcarbonylpipererazines and heteroarylcarbonylpiperazines and their use in the treatment of benign and malignant tumors

Also Published As

Publication number Publication date
DK65177A (da) 1977-08-19
FI821638A7 (fi) 1982-05-10
CY1122A (en) 1981-12-04
JPS52102286A (en) 1977-08-27
FR2348924B1 (enrdf_load_stackoverflow) 1980-05-09
GB1533529A (en) 1978-11-29
FR2348924A1 (fr) 1977-11-18
FI821638L (fi) 1982-05-10
MY8200110A (en) 1982-12-31
YU45477A (en) 1982-10-31
LU76802A1 (enrdf_load_stackoverflow) 1977-09-12
FI770485A7 (enrdf_load_stackoverflow) 1977-08-19
JPS584716B2 (ja) 1983-01-27
YU161282A (en) 1982-10-31
CA1081228A (en) 1980-07-08
FI821638A0 (fi) 1982-05-10
KE3155A (en) 1981-09-18
YU267780A (en) 1983-06-30
CH635838A5 (en) 1983-04-29
SE7701732L (sv) 1977-08-19
YU161182A (en) 1982-10-31
AU2242677A (en) 1978-07-06
DE2707067A1 (de) 1977-08-25
IE44614L (en) 1977-08-18
NL7701753A (nl) 1977-08-22

Similar Documents

Publication Publication Date Title
US4001237A (en) Oxazole, isoxazole, thiazole and isothiazole amides
US4001238A (en) 1,3,4-oxadiazole amides
US4101548A (en) 1,2,3-Thiadiazole amides
US4171363A (en) 1,2,3-Thiadiazole process
US3780040A (en) 2-substituted-3,4-dihydroquinazolines
US20050220784A1 (en) Quinazoline derivatives as medicaments
US20100029673A1 (en) Therapeutic agents comprising an anti-angiogenic agent in combination with an src-inhibitor and their therapeutic use
AU6133499A (en) Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use
KR880002234B1 (ko) 4-아닐리노피리미딘 유도체의 제조방법
EP2650286A1 (en) Quinazoline derivatives and therapeutic use thereof
NZ198308A (en) Heterocyclic substituted isoquinoline derivatives
NZ333369A (en) 7-(2-imidazolinylamino)quinoline compounds useful for treating respiratory, ocular and/or gastrointestinal disorders
KR20030085005A (ko) 진양제
US20210155604A1 (en) Quinazoline compound serving as egfr triple mutation inhibitor and applications thereof
US5523317A (en) Method of reducing blood pressure
JP2002541246A (ja) 抗ウイルス性ピリミジンジオン誘導体及びそれらの製造方法
IE44614B1 (en) 4-amino-6,7-dimethoxy-2-(4-(heterocyclylcarbonyl) piperazin-1-yl) quinazolines
RU2236407C2 (ru) Производные пиримидина
EP0129258A1 (en) Imidazoquinazoline compound
US4711883A (en) Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1H,3H) diones, methods of preparation, compositions and method of use
US7674792B2 (en) 5(Z)-5-(6-quinoxalinylmethylidene)-2-[2,6-dichlorophenyl)amino]-1,3-thiazol-4(5H)-one
JP3265083B2 (ja) ２−［２−（置換アミノ）ベンジルチオ］−５，６，７，８−テトラヒドロ−４（３ｈ）−キナゾリノン誘導体
KR20150002952A (ko) 피리도피리미딘 유도체를 함유하는 대사성 골 질환의 예방 및 치료용 약학 조성물
CA1274830A (en) Intermediates useful for preparing substituted 3-(4- phenyl-1-piperazinyl)alkylquinazolin-2,4-(1h,3h) diones
WO2004087120A2 (en) Use of quinazoline derivatives with src kinase inhibitory activity for the treatment of hypertension