IE44019B1 - 4,5-diaryl substituted imidazoles - Google Patents

4,5-diaryl substituted imidazoles

Info

Publication number
IE44019B1
IE44019B1 IE1775/76A IE177576A IE44019B1 IE 44019 B1 IE44019 B1 IE 44019B1 IE 1775/76 A IE1775/76 A IE 1775/76A IE 177576 A IE177576 A IE 177576A IE 44019 B1 IE44019 B1 IE 44019B1
Authority
IE
Ireland
Prior art keywords
compound
composition
alkyl
imidazole
compounds
Prior art date
Application number
IE1775/76A
Other languages
English (en)
Other versions
IE44019L (en
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of IE44019L publication Critical patent/IE44019L/xx
Publication of IE44019B1 publication Critical patent/IE44019B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IE1775/76A 1975-08-11 1976-08-11 4,5-diaryl substituted imidazoles IE44019B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60365075A 1975-08-11 1975-08-11
US69128276A 1976-06-09 1976-06-09

Publications (2)

Publication Number Publication Date
IE44019L IE44019L (en) 1977-02-11
IE44019B1 true IE44019B1 (en) 1981-07-29

Family

ID=27084480

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1775/76A IE44019B1 (en) 1975-08-11 1976-08-11 4,5-diaryl substituted imidazoles

Country Status (26)

Country Link
JP (1) JPS6011702B2 (show.php)
AR (2) AR215591A1 (show.php)
AU (1) AU508605B2 (show.php)
CA (1) CA1074327A (show.php)
CH (1) CH638791A5 (show.php)
DD (1) DD126244A5 (show.php)
DE (1) DE2635876A1 (show.php)
DK (1) DK361376A (show.php)
ES (2) ES450601A1 (show.php)
FI (1) FI66177C (show.php)
FR (1) FR2320745A1 (show.php)
GB (1) GB1516908A (show.php)
GR (1) GR61145B (show.php)
HU (1) HU174707B (show.php)
IE (1) IE44019B1 (show.php)
IL (1) IL50230A (show.php)
LU (1) LU75578A1 (show.php)
MX (1) MX3932E (show.php)
NL (1) NL7608915A (show.php)
NO (1) NO146571C (show.php)
NZ (1) NZ181731A (show.php)
PH (1) PH11857A (show.php)
PT (1) PT65464B (show.php)
SE (1) SE428686B (show.php)
SU (1) SU640662A3 (show.php)
YU (1) YU198176A (show.php)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK16778A (da) * 1977-02-09 1978-08-10 Du Pont Imidazolderivater deres anvendelser og fremstilling
LU77703A1 (de) * 1977-07-07 1979-03-26 Ciba Geigy Ag Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen
EP0004648B1 (de) * 1978-04-11 1982-08-25 Ciba-Geigy Ag Neue Mercaptoimidazolderivate, Verfahren zu deren Herstellung, Mercaptoimidazolderivate zur Behandlung entzündlicher Erkrankungen und diese enthaltende pharmazeutische Präparate
DE2823197A1 (de) * 1978-05-24 1979-11-29 Schering Ag Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4308277A (en) * 1978-08-10 1981-12-29 Ciba-Geigy Corporation 2,4,5-Trisubstituted imidazolines and pharmaceutical compositions containing same
US4188397A (en) * 1978-09-22 1980-02-12 Smithkline Corporation 2,2-Alkyldiylbis(thio)bis(imidazoles)
US4215135A (en) * 1979-06-08 1980-07-29 E. I. Du Pont De Nemours And Company Antiinflammatory 2-substituted-1H-phenanthro[9,10-d]imidazoles
DE2856909A1 (de) * 1978-12-28 1980-07-17 Schering Ag Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
GB8907656D0 (en) * 1989-04-05 1989-05-17 May & Baker Ltd New compositions of matter
CN1093535C (zh) * 1994-09-26 2002-10-30 盐野义制药株式会社 咪唑衍生物
US6040320A (en) * 1997-06-30 2000-03-21 Ortho-Mcneil Pharmaceutical, Inc. 2-substituted imidazoles useful in the treatment of inflammatory diseases
DE10222103A1 (de) * 2002-05-17 2003-11-27 Merckle Gmbh Chem Pharm Fabrik 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie
WO2007091570A1 (ja) * 2006-02-06 2007-08-16 Taisho Pharmaceutical Co., Ltd. スフィンゴシン－１－リン酸結合阻害物質

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE688585A (show.php) * 1965-10-21 1967-04-20
US3651080A (en) * 1969-11-07 1972-03-21 Ciba Geigy Corp Certain substituted 2-alkylmercaptoimidazole derivatives
US3636003A (en) * 1969-11-17 1972-01-18 Geigy Chem Corp Substituted 2-mercaptoimidazole derivatives
US3714179A (en) * 1970-09-08 1973-01-30 Searle & Co 1-alkyl-2-furfurylthioimidazoles and congeners
US3707475A (en) * 1970-11-16 1972-12-26 Pfizer Antiinflammatory imidazoles

Also Published As

Publication number Publication date
DK361376A (da) 1977-02-12
GB1516908A (en) 1978-07-05
SE7607615L (sv) 1977-02-12
ES450601A1 (es) 1978-01-16
IL50230A0 (en) 1976-10-31
ES461193A1 (es) 1978-12-01
AU1671176A (en) 1978-02-16
YU198176A (en) 1982-10-31
NO146571C (no) 1982-10-27
DD126244A5 (show.php) 1977-07-06
CH638791A5 (de) 1983-10-14
GR61145B (en) 1978-09-27
MX3932E (es) 1981-10-02
IE44019L (en) 1977-02-11
SU640662A3 (ru) 1978-12-30
NZ181731A (en) 1978-11-13
JPS5223076A (en) 1977-02-21
NL7608915A (nl) 1977-02-15
FI66177C (fi) 1984-09-10
NO762754L (show.php) 1977-02-14
FI762290A7 (show.php) 1977-02-12
PT65464B (en) 1978-08-02
LU75578A1 (show.php) 1978-04-13
DE2635876A1 (de) 1977-03-03
CA1074327A (en) 1980-03-25
NO146571B (no) 1982-07-19
AR218054A1 (es) 1980-05-15
PH11857A (en) 1978-08-03
JPS6011702B2 (ja) 1985-03-27
AU508605B2 (en) 1980-03-27
SE428686B (sv) 1983-07-18
FR2320745A1 (fr) 1977-03-11
PT65464A (en) 1976-09-01
AR215591A1 (es) 1979-10-31
IL50230A (en) 1979-07-25
FI66177B (fi) 1984-05-31
FR2320745B1 (show.php) 1978-12-22
HU174707B (hu) 1980-03-28

Similar Documents

Publication Publication Date Title
US4190666A (en) Anti-inflammatory 4,5-diarly-2-(substituted-thio)imidazoles and their corresponding sulfoxides and sulfones
CA1107286A (en) Anti-inflammatory 1-substituted-4,5-diaryl-2- (substituted-thio) imidazoles and their corresponding sulfoxides and sulfones
US4302461A (en) Antiinflammatory 5-substituted-2,3-diarylthiophenes
CA1144550A (en) Antiinflammatory 4,5-diaryl-2-(substituted-thio) pyrroles and their corresponding sulfoxides and sulfones
US4198421A (en) Antiinflammatory 2-substituted-dibenzo[2,3:6,7]oxepino[4,5-d]imidazoles
IE44019B1 (en) 4,5-diaryl substituted imidazoles
US4438117A (en) 2-Substituted thio-4,5-diarylpyrimidines
US4159338A (en) Antiinflammatory-4,5-dicyclic-2-(substituted thio)-imidazoles and their corresponding sulfoxides and sulfones
US5110831A (en) Vinylogous hydroxamic acids and derivatives thereof as 5-lipoxygenase inhibitors
US4652582A (en) Antiinflammatory-2-halo-4,5-diarylpyrroles
US5298521A (en) 1,5-diphenyl-3-pyrazolylalkyl-N-hydroxydithiocaramates, compositions and use
US4267190A (en) Antiinflammatory 4,5-diaryl-α,α-bis(polyfluoromethyl)-1H-pyrrole-2-methanethiols
FI79308B (fi) Foerfarande foer framstaellning av som antiinflammatoriska medel anvaendbara 2,3-diaryl-5-halogentiofener.
NZ196860A (en) 4,5-diaryl-alpha-(polyfluoroalkyl)-1h-pyrrole-2-methanamine derivatives and pharmaceutical compositions
GB1564184A (en) Antiinflammatory 4,5-dicyclic-2-(substituted thio)-imidazoles and their corresponding sulphoxides and sulphones
US4215135A (en) Antiinflammatory 2-substituted-1H-phenanthro[9,10-d]imidazoles
EP0011115B1 (en) Antiinflammatory 2-substituted-1h-phenanthro(9,10-d)imidazoles, their preparation and pharmaceutical compositions containing them
EP0294994B1 (en) 3-4-Dihydro-2-alkyl-3-oxo-N-aryl-2H-[1]benzothieno[3,2-el]-1,2-thiazine-4-carboxamide-1,1-dioxides
US4548946A (en) Antiinflammatory and/or analgesic 1,8-Dihydro-(or 3,8-dihydro)-8-aryl-2-[(substituted)thio]-indeno[1,2-d]imidazoles and their corresponding sulfoxides and sulfones
US4379159A (en) Antiinflammatory 2-substituted-thio-4,5-dihydro-4,5-diaryl-1H-imidazoles
EP0419561A1 (en) Heterobicyclic compounds having antiinflammatory activity
JPS6028837B2 (ja) ジアリ−ルチオフエン化合物、その製造法およびそれを含有する抗炎症剤
BE845074A (fr) Nouveaux agents antiinflammatoires imidazoles, leur preparation et compositions pharmaceutiques
US3997670A (en) 1-Dioxolanylpropyl-3-indoleacrylic acid esters
JPH02275870A (ja) １，４―チアジン誘導体