IE43132B1 - Cis-bicyclooctyl-alkyl-amine derivatives - Google Patents

Cis-bicyclooctyl-alkyl-amine derivatives

Info

Publication number
IE43132B1
IE43132B1 IE797/76A IE79776A IE43132B1 IE 43132 B1 IE43132 B1 IE 43132B1 IE 797/76 A IE797/76 A IE 797/76A IE 79776 A IE79776 A IE 79776A IE 43132 B1 IE43132 B1 IE 43132B1
Authority
IE
Ireland
Prior art keywords
formula
bicyclo
acid
cis
addition salt
Prior art date
Application number
IE797/76A
Other languages
English (en)
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of IE43132B1 publication Critical patent/IE43132B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/69—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IE797/76A 1975-05-08 1976-04-14 Cis-bicyclooctyl-alkyl-amine derivatives IE43132B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB19348/75A GB1549174A (en) 1975-05-08 1975-05-08 Amine derivatives

Publications (1)

Publication Number Publication Date
IE43132B1 true IE43132B1 (en) 1980-12-31

Family

ID=10127854

Family Applications (1)

Application Number Title Priority Date Filing Date
IE797/76A IE43132B1 (en) 1975-05-08 1976-04-14 Cis-bicyclooctyl-alkyl-amine derivatives

Country Status (38)

Country Link
US (1) US4705807A (en, 2012)
JP (1) JPS6039069B2 (en, 2012)
AR (2) AR211926A1 (en, 2012)
AT (1) AT346825B (en, 2012)
AU (1) AU503324B2 (en, 2012)
BE (1) BE841634A (en, 2012)
BG (1) BG28043A3 (en, 2012)
CA (1) CA1077500A (en, 2012)
CH (1) CH609672A5 (en, 2012)
CS (1) CS196406B2 (en, 2012)
CY (1) CY1151A (en, 2012)
DD (1) DD123988A5 (en, 2012)
DE (1) DE2619617A1 (en, 2012)
DK (1) DK147577C (en, 2012)
ES (1) ES447715A1 (en, 2012)
FI (1) FI61868C (en, 2012)
FR (1) FR2310126A1 (en, 2012)
GB (1) GB1549174A (en, 2012)
GR (1) GR59904B (en, 2012)
HK (1) HK25682A (en, 2012)
HU (1) HU176277B (en, 2012)
IE (1) IE43132B1 (en, 2012)
IL (1) IL49438A (en, 2012)
LU (1) LU74896A1 (en, 2012)
MX (1) MX3454E (en, 2012)
MY (1) MY8300054A (en, 2012)
NL (1) NL7604882A (en, 2012)
NO (1) NO142218C (en, 2012)
NZ (1) NZ180657A (en, 2012)
OA (1) OA05206A (en, 2012)
PH (1) PH13678A (en, 2012)
PL (2) PL103979B1 (en, 2012)
PT (1) PT65074B (en, 2012)
RO (1) RO70770A (en, 2012)
SE (2) SE426585B (en, 2012)
SU (2) SU602112A3 (en, 2012)
YU (1) YU113576A (en, 2012)
ZA (1) ZA762378B (en, 2012)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215074A (en) * 1978-07-15 1980-07-29 Lilly Industries Limited Process for preparing cis-bicyclooctylamines
CA1130318A (en) * 1978-10-11 1982-08-24 Peter M. Muller Cyclohexadiene derivatives
US5098916A (en) * 1990-03-29 1992-03-24 G. D. Searle & Co. Propanobicyclic amine derivatives for cns disorders
DE4019782A1 (de) * 1990-06-21 1992-01-02 Basf Ag 9-amino-2-phenylbicyclo (3.3.1.) und 9-amino-2-phenylbicyclo (3.3.1.) non-2-ene und diese enthaltende therapeutische mittel
GB9908021D0 (en) * 1999-04-08 1999-06-02 Lilly Co Eli Pharmaceutical compounds
GB2367554A (en) * 2000-10-04 2002-04-10 Lilly Co Eli Pharmacologically active amines

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB873018A (en) * 1958-09-22 1961-07-19 Smith Kline French Lab Substituted phenylcyclopropylamines
US3133901A (en) * 1960-08-11 1964-05-19 Mcneilab Inc Aminonorbornanes and their preparation
GB992734A (en) * 1961-11-10 1965-05-19 Smith Kline French Lab Improvements in or relating to novel trans-3-phenylcyclobutylamines
US3308160A (en) * 1963-06-26 1967-03-07 Du Pont 4-phenylbicyclo[2.2.2]octane-1-amines and salts thereof
US3413348A (en) * 1965-06-28 1968-11-26 Du Pont 4-phenylbicyclo[2.2.2.]oct-2-ene-1-amine and salts thereof
US3362878A (en) * 1966-08-01 1968-01-09 Du Pont Pharmaceutical compositions and methods utilizing substituted bicyclo[2.2.2]-octanes
US3742055A (en) * 1969-07-31 1973-06-26 Colgate Palmolive Co 3-amino-bicyclo{8 2.2.2{9 octan-2-ols
US3980785A (en) * 1972-11-04 1976-09-14 Lilly Industries, Ltd. Secondary and tertiary-2-phenylbicyclo[2,2,2]oct-3-yl alkylamines and composition thereof
GB1444717A (en) * 1972-11-04 1976-08-04 Lilly Industries Ltd Bicycloalkyl derivatives

Also Published As

Publication number Publication date
DK147577B (da) 1984-10-08
RO70770A (ro) 1981-11-04
CS196406B2 (en) 1980-03-31
JPS6039069B2 (ja) 1985-09-04
FR2310126A1 (fr) 1976-12-03
SE426585B (sv) 1983-01-31
JPS51138661A (en) 1976-11-30
FR2310126B1 (en, 2012) 1980-07-04
SE7605146L (sv) 1976-11-09
CY1151A (en) 1982-09-10
YU113576A (en) 1983-01-21
FI61868C (fi) 1982-10-11
MY8300054A (en) 1983-12-31
FI761292A7 (en, 2012) 1976-11-09
HK25682A (en) 1982-06-18
AR211926A1 (es) 1978-04-14
CH609672A5 (en, 2012) 1979-03-15
NO761550L (en, 2012) 1976-11-09
PT65074A (en) 1976-06-01
PL106888B1 (pl) 1980-01-31
DE2619617A1 (de) 1976-11-18
AU1375576A (en) 1977-11-10
BE841634A (fr) 1976-11-08
DD123988A5 (en, 2012) 1977-01-26
ES447715A1 (es) 1977-06-01
PL103979B1 (pl) 1979-07-31
SU680642A3 (ru) 1979-08-15
GR59904B (en) 1978-03-16
ATA328376A (de) 1978-04-15
HU176277B (en) 1981-01-28
PT65074B (en) 1978-05-08
AR218619A1 (es) 1980-06-30
GB1549174A (en) 1979-08-01
NO142218C (no) 1980-07-16
SU602112A3 (ru) 1978-04-05
BG28043A3 (bg) 1980-02-25
AU503324B2 (en) 1979-08-30
NL7604882A (nl) 1976-11-10
IL49438A (en) 1980-01-31
SE431641B (sv) 1984-02-20
OA05206A (fr) 1981-02-28
NZ180657A (en) 1978-06-20
IL49438A0 (en) 1976-06-30
ZA762378B (en) 1977-04-27
SE8000363L (sv) 1980-01-16
PH13678A (en) 1980-08-29
DK202876A (da) 1976-11-09
AT346825B (de) 1978-11-27
NO142218B (no) 1980-04-08
DE2619617C2 (en, 2012) 1987-10-01
DK147577C (da) 1985-03-18
FI61868B (fi) 1982-06-30
US4705807A (en) 1987-11-10
MX3454E (es) 1980-12-03
LU74896A1 (en, 2012) 1977-12-13
CA1077500A (en) 1980-05-13

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