IE41562B1 - Indolinone and fluorenone derivatives - Google Patents
Indolinone and fluorenone derivativesInfo
- Publication number
- IE41562B1 IE41562B1 IE1359/75A IE135975A IE41562B1 IE 41562 B1 IE41562 B1 IE 41562B1 IE 1359/75 A IE1359/75 A IE 1359/75A IE 135975 A IE135975 A IE 135975A IE 41562 B1 IE41562 B1 IE 41562B1
- Authority
- IE
- Ireland
- Prior art keywords
- compound
- group
- het
- fluorenone
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
- C07D203/10—Radicals substituted by singly bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH838174A CH602710A5 (en) | 1974-06-19 | 1974-06-19 | Substd. 9-fluorenone and 2-indolinone derivs |
| CH838074A CH599160A5 (en) | 1974-06-19 | 1974-06-19 | Substd. 9-fluorenone and 2-indolinone derivs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE41562L IE41562L (en) | 1975-12-19 |
| IE41562B1 true IE41562B1 (en) | 1980-01-30 |
Family
ID=25703229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1359/75A IE41562B1 (en) | 1974-06-19 | 1975-06-17 | Indolinone and fluorenone derivatives |
Country Status (18)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0005828B1 (de) * | 1978-06-06 | 1981-03-11 | Hoechst Aktiengesellschaft | Neue substituierte Phenylpiperazinderivate, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung |
| EA006301B1 (ru) | 1999-01-22 | 2005-10-27 | Элан Фармасьютикалз, Инк. | Ацильные производные, используемые для лечения опосредованных vla-4 расстройств |
| TW200307671A (en) | 2002-05-24 | 2003-12-16 | Elan Pharm Inc | Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins |
| TWI281470B (en) | 2002-05-24 | 2007-05-21 | Elan Pharm Inc | Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins |
| BRPI0616643A2 (pt) | 2005-09-29 | 2011-06-28 | Elan Pharm Inc | compostos de carbamato que inibem a adesão leucocitária mediada por vla-4 |
| JP5101512B2 (ja) | 2005-09-29 | 2012-12-19 | エラン ファーマシューティカルズ，インコーポレイテッド | Ｖｌａ−４によって媒介される白血球接着を阻害するピリミジニルアミド化合物 |
| AU2007220068B2 (en) | 2006-02-27 | 2012-09-13 | Elan Pharmaceuticals, Inc. | Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| US8367836B2 (en) | 2009-04-27 | 2013-02-05 | Elan Pharmaceuticals, Inc. | Pyridinone antagonists of alpha-4 integrins |
-
1975
- 1975-06-09 DE DE19752525656 patent/DE2525656A1/de active Pending
- 1975-06-10 DK DK259475A patent/DK259475A/da unknown
- 1975-06-10 FI FI751727A patent/FI751727A7/fi unknown
- 1975-06-11 NO NO752078A patent/NO752078L/no unknown
- 1975-06-12 SE SE7506757A patent/SE7506757L/xx unknown
- 1975-06-16 GB GB25530/75A patent/GB1500063A/en not_active Expired
- 1975-06-16 NL NL7507131A patent/NL7507131A/xx not_active Application Discontinuation
- 1975-06-17 IE IE1359/75A patent/IE41562B1/en unknown
- 1975-06-17 AU AU82168/75A patent/AU8216875A/en not_active Expired
- 1975-06-17 ES ES438637A patent/ES438637A1/es not_active Expired
- 1975-06-17 HU HUSA2805A patent/HU169926B/hu unknown
- 1975-06-17 FR FR7518882A patent/FR2275200A1/fr active Granted
- 1975-06-17 DD DD186699A patent/DD118086A5/xx unknown
- 1975-06-17 IL IL47503A patent/IL47503A0/xx unknown
- 1975-06-18 JP JP50073280A patent/JPS51125060A/ja active Pending
- 1975-06-18 CA CA229,607A patent/CA1036163A/en not_active Expired
- 1975-06-18 AT AT466375A patent/ATA466375A/de not_active Application Discontinuation
- 1975-06-19 SU SU7502145931A patent/SU583755A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| HU169926B (enrdf_load_stackoverflow) | 1977-02-28 |
| NO752078L (enrdf_load_stackoverflow) | 1975-12-22 |
| FI751727A7 (enrdf_load_stackoverflow) | 1975-12-20 |
| ES438637A1 (es) | 1977-06-01 |
| FR2275200A1 (fr) | 1976-01-16 |
| GB1500063A (en) | 1978-02-08 |
| IE41562L (en) | 1975-12-19 |
| NL7507131A (nl) | 1975-12-23 |
| DK259475A (da) | 1975-12-20 |
| AU8216875A (en) | 1976-12-23 |
| CA1036163A (en) | 1978-08-08 |
| DD118086A5 (enrdf_load_stackoverflow) | 1976-02-12 |
| FR2275200B1 (enrdf_load_stackoverflow) | 1979-06-08 |
| IL47503A0 (en) | 1975-08-31 |
| DE2525656A1 (de) | 1976-01-15 |
| ATA466375A (de) | 1979-08-15 |
| JPS51125060A (en) | 1976-11-01 |
| SE7506757L (sv) | 1975-12-22 |
| SU583755A3 (ru) | 1977-12-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US3399192A (en) | 1-oxa-2-oxo 3, 8-diaza spiro (4, 5) decanes | |
| CZ452390A3 (cs) | Estery thienylkarboxylových kyselin s aminoalkoholy, způsob jejich výroby, jejich použití a farmaceutický prostředek s jejich obsahem | |
| WO1990014347A1 (en) | Indole derivatives and medicine | |
| IE41562B1 (en) | Indolinone and fluorenone derivatives | |
| IL26969A (en) | Bis-(3-indole-alkylene or oxoalkylene)-azacyclic or diazacyclic compounds and their preparation | |
| CA1098909A (en) | Indolyloxy-aminopropanol derivatives | |
| JPS595577B2 (ja) | チカンサレテイル サンカンシキアミノアルコ−ルノ セイホウ | |
| US3407199A (en) | Tertiaryamino ethyl or propyl pyrrol-2-yl ketones | |
| US4137331A (en) | 3-Piperidino-2-hydroxypropoxy substituted-2-indolinones | |
| US3758502A (en) | Organic compounds | |
| KR800000058B1 (ko) | 벤조사이클로헾타티오펜 유도체의 제조방법 | |
| US2802003A (en) | Derivatives of 3-azabicycloheptane | |
| US3563998A (en) | 2 - (4 - (2',6' - diphenyl - 4 - pyridyl)phenoxy)-and 2 - (4 - (4',6' - diphenyl - 2 -pyridyl)phenoxy) lower aliphatic monocarbocylic acids and esters | |
| JPH02138161A (ja) | 置換ケイ皮酸アミド誘導体 | |
| US3308129A (en) | 3-tropanyl esters of atropic and thioatropic acids | |
| US3644343A (en) | Phenyl and substituted phenylsulfonylallyl amines and substituted amines | |
| US3726868A (en) | Phenyl and substituted phenylsulfonylallyl amines and substituted amines | |
| US3462447A (en) | Certain azadibenzocycloheptene-5-ols and ethers derivatives thereof | |
| US3526632A (en) | Derivatives of bis-(4-biphenylyloxy)acetic acid | |
| KR790000943B1 (ko) | 복소환 화합물의 제조방법 | |
| US2913459A (en) | New quaternary ammonium compounds and process for the production thereof | |
| JPS5815977A (ja) | トリアジノ−（２，１−ａ）イソキノリン誘導体 | |
| JPH06510990A (ja) | ５−ｈｔ３受容体拮抗活性を有する３，９−ジアザビシクロ（３．３．１）ノナン誘導体 | |
| US3634434A (en) | 3- or 4-dichloromethylene-piperidines | |
| US3787410A (en) | Carboxyamido substituted-2-alkylthio-5-pyrimidinesulfonamides |