IE40660B1 - 2-deoxy-2-nicotinamido-1-nicotinoyl-glucopyranose derivatives, methods for their preparation and compositions containing them - Google Patents
2-deoxy-2-nicotinamido-1-nicotinoyl-glucopyranose derivatives, methods for their preparation and compositions containing themInfo
- Publication number
- IE40660B1 IE40660B1 IE98/75A IE9875A IE40660B1 IE 40660 B1 IE40660 B1 IE 40660B1 IE 98/75 A IE98/75 A IE 98/75A IE 9875 A IE9875 A IE 9875A IE 40660 B1 IE40660 B1 IE 40660B1
- Authority
- IE
- Ireland
- Prior art keywords
- acetyl
- prepared
- nicotinoyl
- compound
- nicotinamido
- Prior art date
Links
- KRUUQSSUPBZEMV-WWLSQLEVSA-N N-[(3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)-2-(pyridine-3-carbonyl)oxan-3-yl]pyridine-3-carboxamide Chemical class C(C1=CN=CC=C1)(=O)N[C@H]1C(O)(O[C@@H]([C@H]([C@@H]1O)O)CO)C(C1=CN=CC=C1)=O KRUUQSSUPBZEMV-WWLSQLEVSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 3
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 abstract 2
- 125000001589 carboacyl group Chemical group 0.000 abstract 2
- NIXJAWQDKYNCMP-FQOSCAEFSA-N N-[(3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]pyridine-3-carboxamide Chemical compound O[C@H]1[C@H](O)[C@@H](CO)OC(O)[C@@H]1NC(=O)C1=CC=CN=C1 NIXJAWQDKYNCMP-FQOSCAEFSA-N 0.000 abstract 1
- ZRAWPYYLRZSVEU-GNMOMJPPSA-N [(2r,3s,4r,5r)-3,4,6-triacetyloxy-5-aminooxan-2-yl]methyl acetate Chemical compound CC(=O)OC[C@H]1OC(OC(C)=O)[C@H](N)[C@@H](OC(C)=O)[C@@H]1OC(C)=O ZRAWPYYLRZSVEU-GNMOMJPPSA-N 0.000 abstract 1
- WETWJCDKMRHUPV-UHFFFAOYSA-N acetyl chloride Chemical compound CC(Cl)=O WETWJCDKMRHUPV-UHFFFAOYSA-N 0.000 abstract 1
- 239000012346 acetyl chloride Substances 0.000 abstract 1
- 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 235000005152 nicotinamide Nutrition 0.000 abstract 1
- 235000001968 nicotinic acid Nutrition 0.000 abstract 1
- 229960003512 nicotinic acid Drugs 0.000 abstract 1
- 239000011664 nicotinic acid Substances 0.000 abstract 1
- -1 nicotinoyloxy group Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH103974A CH597253A5 (enrdf_load_stackoverflow) | 1974-01-25 | 1974-01-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE40660L IE40660L (en) | 1975-07-25 |
| IE40660B1 true IE40660B1 (en) | 1979-07-18 |
Family
ID=4201023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE98/75A IE40660B1 (en) | 1974-01-25 | 1975-01-20 | 2-deoxy-2-nicotinamido-1-nicotinoyl-glucopyranose derivatives, methods for their preparation and compositions containing them |
Country Status (23)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH640411A5 (de) * | 1978-05-26 | 1984-01-13 | Kureha Chemical Ind Co Ltd | Medikament zur behandlung von hyperglykaemie, hyperlipaemie, hypertension, entzuendungen, schmerz, fieber oder tumoren. |
| IT1140962B (it) * | 1980-05-20 | 1986-10-10 | Guidotti & C Spa Labor | Derivati nicotinici di glucosamina, procedimento per la preparazione e relative composizioni |
| ATE8635T1 (de) * | 1980-11-27 | 1984-08-15 | F. Hoffmann-La Roche & Co. Aktiengesellschaft | Verfahren zur herstellung eines beta-dglucopyranosederivates. |
-
1974
- 1974-01-25 CH CH103974A patent/CH597253A5/xx not_active IP Right Cessation
- 1974-11-26 ZA ZA00747566A patent/ZA747566B/xx unknown
- 1974-11-29 IL IL46154A patent/IL46154A/en unknown
- 1974-12-09 CA CA215,544A patent/CA1024511A/en not_active Expired
- 1974-12-11 NL NL7416126A patent/NL7416126A/xx not_active Application Discontinuation
- 1974-12-18 YU YU3370/74A patent/YU36740B/xx unknown
- 1974-12-23 AR AR257050A patent/AR208532A1/es active
- 1974-12-27 DK DK683074A patent/DK143566C/da not_active IP Right Cessation
- 1974-12-30 FI FI3785/74A patent/FI61193C/fi active
-
1975
- 1975-01-02 PH PH16663A patent/PH10795A/en unknown
- 1975-01-15 HU HUHO1762A patent/HU170430B/hu unknown
- 1975-01-17 DE DE2501861A patent/DE2501861C2/de not_active Expired
- 1975-01-20 IE IE98/75A patent/IE40660B1/xx unknown
- 1975-01-22 SE SE7500692A patent/SE412395B/xx unknown
- 1975-01-23 LU LU71705A patent/LU71705A1/xx unknown
- 1975-01-23 DD DD183779A patent/DD117453A5/xx unknown
- 1975-01-23 FR FR7502125A patent/FR2258861B1/fr not_active Expired
- 1975-01-23 SU SU2099880A patent/SU543355A3/ru active
- 1975-01-24 AT AT54075A patent/AT343144B/de not_active IP Right Cessation
- 1975-01-24 NO NO750228A patent/NO140598C/no unknown
- 1975-01-24 GB GB318075A patent/GB1451181A/en not_active Expired
- 1975-01-24 BE BE152662A patent/BE824729A/xx not_active IP Right Cessation
- 1975-01-24 JP JP50010376A patent/JPS50160278A/ja active Pending
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