IE36120B1 - New pregnane acid derivatives - Google Patents

New pregnane acid derivatives

Info

Publication number
IE36120B1
IE36120B1 IE227/72A IE22772A IE36120B1 IE 36120 B1 IE36120 B1 IE 36120B1 IE 227/72 A IE227/72 A IE 227/72A IE 22772 A IE22772 A IE 22772A IE 36120 B1 IE36120 B1 IE 36120B1
Authority
IE
Ireland
Prior art keywords
halogen
acid derivatives
inflammatory
new
new pregnane
Prior art date
Application number
IE227/72A
Other versions
IE36120L (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19712150268 external-priority patent/DE2150268C3/en
Priority claimed from DE2204360A external-priority patent/DE2204360C2/en
Priority claimed from DE2204358A external-priority patent/DE2204358C2/en
Priority claimed from DE2204361A external-priority patent/DE2204361A1/en
Application filed by Schering Ag filed Critical Schering Ag
Publication of IE36120L publication Critical patent/IE36120L/en
Publication of IE36120B1 publication Critical patent/IE36120B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0095Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 carbon in position 21 is part of carboxylic group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1387911 Anti-inflammatory medicines SCHERING AG 23 Feb 1972 [4 Oct 1971 27 Jan 1972 (3)] 8299/72 Heading A5B [Also in Division C2] Anti-inflammatory compositions comprise steroids of the formula: (wherein X is H, halogen or CH 3 ; Y is H or halogen; Z is OH, or, when Y is halogen, is halogen of atomic weight equal to or less than that of Y; R 1 is H or CH 3 ; R 2 is H, an alkali metal atom or an optionally substituted hydrocarbon group; and -A-B- is -CH=CH-, -CC1=CH- or -CH 2 -CH 2 -; but X, Y and R 1 are not all H when #1 is absent) and suitable carriers. They may also contain bacteriostatic agents such as chloramphenicol. Examples describe the preparation of ointments and eye and ear drops.
IE227/72A 1971-10-04 1972-02-24 New pregnane acid derivatives IE36120B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19712150268 DE2150268C3 (en) 1971-10-04 1971-10-04 Pregnanic acid derivatives, processes for their preparation and pharmaceuticals containing them
DE2204360A DE2204360C2 (en) 1972-01-27 1972-01-27 New pregnanic acid derivatives, processes for their production and pharmaceutical preparations containing them
DE2204358A DE2204358C2 (en) 1972-01-27 1972-01-27 Process for the preparation of pregnanic acid derivatives
DE2204361A DE2204361A1 (en) 1972-01-27 1972-01-27 3, 20-dioxo-pregnene and pregnadiene 21-acids - antiinflammatories for topical application

Publications (2)

Publication Number Publication Date
IE36120L IE36120L (en) 1973-04-04
IE36120B1 true IE36120B1 (en) 1976-08-18

Family

ID=27431338

Family Applications (1)

Application Number Title Priority Date Filing Date
IE227/72A IE36120B1 (en) 1971-10-04 1972-02-24 New pregnane acid derivatives

Country Status (18)

Country Link
JP (1) JPS5837320B2 (en)
BE (1) BE779869A (en)
CA (1) CA978518A (en)
CH (2) CH589671A5 (en)
DD (1) DD95565B1 (en)
DK (1) DK136612C (en)
EG (1) EG10635A (en)
FI (1) FI51103C (en)
FR (1) FR2156518B1 (en)
GB (1) GB1387911A (en)
HU (1) HU165261B (en)
IE (1) IE36120B1 (en)
IL (1) IL39735A (en)
LU (1) LU66213A1 (en)
NL (1) NL179059C (en)
NO (1) NO138808C (en)
RO (2) RO71183A (en)
YU (1) YU35148B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK135380C (en) * 1972-12-22 1977-10-03 Schering Ag ANALOGICAL PROCEDURE FOR PREGNAN-21 ACID DERIVATIVES
DE2444618C2 (en) * 1974-09-16 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen New Pregnan-21-Acid-Derivatives
DE2365102C2 (en) * 1973-12-21 1982-12-02 Schering Ag, 1000 Berlin Und 4619 Bergkamen New pregnanic acid derivatives
DE2332663C2 (en) * 1973-06-23 1986-07-31 Schering AG, 1000 Berlin und 4709 Bergkamen Use of corticosteroid active ingredients for inhalation therapy
DE2336438C2 (en) * 1973-07-14 1983-07-07 Schering Ag, 1000 Berlin Und 4619 Bergkamen Process for making 17β-oxalyl steroids
DE2862012D1 (en) * 1978-06-12 1982-10-28 Schering Ag New corticoids, processes for their preparation and pharmaceutical compositions containing them
US5215979A (en) * 1985-12-19 1993-06-01 Aktiebolaget Draco 16,17-acetalsubstituted pregnane 21-oic acid derivatives
SE8506015D0 (en) * 1985-12-19 1985-12-19 Draco Ab NOVEL 16,17-ACETALSUBSTITUTED PREGNANE 21-OIC ACID DERIVATIVES
JP2007237153A (en) * 2006-03-06 2007-09-20 Npo Machinami Ikuseikai Air mixing and agitation technology

Also Published As

Publication number Publication date
RO71183A (en) 1983-08-03
NL7213456A (en) 1973-04-06
FR2156518A1 (en) 1973-06-01
YU44372A (en) 1980-03-15
DK136612C (en) 1978-04-10
NO138808B (en) 1978-08-07
FI51103C (en) 1976-10-11
RO70725A (en) 1982-09-09
EG10635A (en) 1976-09-30
HU165261B (en) 1974-07-27
GB1387911A (en) 1975-03-19
NO138808C (en) 1978-11-15
DD95565B1 (en) 1986-10-29
YU35148B (en) 1980-09-25
NL179059B (en) 1986-02-03
RO71183B (en) 1983-07-30
JPS5837320B2 (en) 1983-08-15
DK136612B (en) 1977-10-31
DD95565A5 (en) 1973-02-12
NL179059C (en) 1986-07-01
JPS4861464A (en) 1973-08-28
LU66213A1 (en) 1973-01-23
IL39735A (en) 1975-08-31
CH589671A5 (en) 1977-07-15
BE779869A (en) 1972-08-25
FR2156518B1 (en) 1975-06-13
FI51103B (en) 1976-06-30
IL39735A0 (en) 1972-12-29
IE36120L (en) 1973-04-04
CA978518A (en) 1975-11-25
CH588509A5 (en) 1977-06-15

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