GB1203733A - PREPARATION OF delta< >-3-KETO STEROIDS - Google Patents

PREPARATION OF delta< >-3-KETO STEROIDS

Info

Publication number
GB1203733A
GB1203733A GB1089668A GB1089668A GB1203733A GB 1203733 A GB1203733 A GB 1203733A GB 1089668 A GB1089668 A GB 1089668A GB 1089668 A GB1089668 A GB 1089668A GB 1203733 A GB1203733 A GB 1203733A
Authority
GB
United Kingdom
Prior art keywords
ones
methanol
steroids
trichloroacetoxy
march
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1089668A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
State of Israel
Original Assignee
Yeda Research and Development Co Ltd
State of Israel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research and Development Co Ltd, State of Israel filed Critical Yeda Research and Development Co Ltd
Publication of GB1203733A publication Critical patent/GB1203733A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

1,203,733. #<SP>5</SP>-3-oxo and #<SP>3,5</SP>-3-trichloroacetoxy steroids. ISRAEL MINISTRY OF COMMERCE & INDUSTRY, STATE OF; YEDA RESEARCH & DEVELOPMENT CO. Ltd., and Y. MAZUR. 6 March, 1968 [7 March, 1967], No. 10896/68. Heading C2U. Steroids of formula (wherein R 1 and R 2 are each H or C 1-6 alkyl, - C :D-represents the optionally substituted C and D rings of the steroid, and the dotted line signifies an optional #<SP>7</SP>-unsaturation), which compounds are novel except for 3,1 1#-bis(trichloroacetoxy) 3,5 - androstadien - 17- one,. are prepared from the corresponding #<SP>4</SP>-3-ones or #<SP>4</SP>'<SP>5</SP>-3-ones by reacting with trichloroacetic anhydride, and are convertible into #<SP>5</SP>-3-ones or #<SP>5</SP>'<SP>7</SP>-3-ones by dissolving in spectrum grade methanol or slightly basic methanol, optionally with heating, and evaporating the methanol when the conversion is complete.
GB1089668A 1967-03-07 1968-03-06 PREPARATION OF delta< >-3-KETO STEROIDS Expired GB1203733A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL2755267A IL27552A (en) 1967-03-07 1967-03-07 Preparation of delta5-3-keto steroids

Publications (1)

Publication Number Publication Date
GB1203733A true GB1203733A (en) 1970-09-03

Family

ID=11044135

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1089668A Expired GB1203733A (en) 1967-03-07 1968-03-06 PREPARATION OF delta< >-3-KETO STEROIDS

Country Status (2)

Country Link
GB (1) GB1203733A (en)
IL (1) IL27552A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109627277A (en) * 2018-12-19 2019-04-16 上海新华联制药有限公司 A kind of preparation method of medroxyprogesterone acetate

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109627277A (en) * 2018-12-19 2019-04-16 上海新华联制药有限公司 A kind of preparation method of medroxyprogesterone acetate

Also Published As

Publication number Publication date
IL27552A (en) 1971-03-24

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees