FI51103C - Process for the preparation of anti-inflammatory pregnanoic acid derivatives. - Google Patents

Process for the preparation of anti-inflammatory pregnanoic acid derivatives.

Info

Publication number
FI51103C
FI51103C FI720497A FI49772A FI51103C FI 51103 C FI51103 C FI 51103C FI 720497 A FI720497 A FI 720497A FI 49772 A FI49772 A FI 49772A FI 51103 C FI51103 C FI 51103C
Authority
FI
Finland
Prior art keywords
halogen
inflammatory
preparation
acid derivatives
pregnanoic acid
Prior art date
Application number
FI720497A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI51103B (en
Inventor
Henry Laurent
Rudolf Wiechert
Klaus Prezewowsky
Helmut Hofmeister
Erich Gerhards
Karl Heinz Kolb
Klaus Mengel
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19712150268 external-priority patent/DE2150268C3/en
Priority claimed from DE2204361A external-priority patent/DE2204361A1/en
Priority claimed from DE2204358A external-priority patent/DE2204358C2/en
Priority claimed from DE2204360A external-priority patent/DE2204360C2/en
Application filed by Schering Ag filed Critical Schering Ag
Publication of FI51103B publication Critical patent/FI51103B/fi
Application granted granted Critical
Publication of FI51103C publication Critical patent/FI51103C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0095Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 carbon in position 21 is part of carboxylic group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1387911 Anti-inflammatory medicines SCHERING AG 23 Feb 1972 [4 Oct 1971 27 Jan 1972 (3)] 8299/72 Heading A5B [Also in Division C2] Anti-inflammatory compositions comprise steroids of the formula: (wherein X is H, halogen or CH 3 ; Y is H or halogen; Z is OH, or, when Y is halogen, is halogen of atomic weight equal to or less than that of Y; R 1 is H or CH 3 ; R 2 is H, an alkali metal atom or an optionally substituted hydrocarbon group; and -A-B- is -CH=CH-, -CC1=CH- or -CH 2 -CH 2 -; but X, Y and R 1 are not all H when #<SP>1</SP> is absent) and suitable carriers. They may also contain bacteriostatic agents such as chloramphenicol. Examples describe the preparation of ointments and eye and ear drops.
FI720497A 1971-10-04 1972-02-25 Process for the preparation of anti-inflammatory pregnanoic acid derivatives. FI51103C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19712150268 DE2150268C3 (en) 1971-10-04 1971-10-04 Pregnanic acid derivatives, processes for their preparation and pharmaceuticals containing them
DE2204361A DE2204361A1 (en) 1972-01-27 1972-01-27 3, 20-dioxo-pregnene and pregnadiene 21-acids - antiinflammatories for topical application
DE2204358A DE2204358C2 (en) 1972-01-27 1972-01-27 Process for the preparation of pregnanic acid derivatives
DE2204360A DE2204360C2 (en) 1972-01-27 1972-01-27 New pregnanic acid derivatives, processes for their production and pharmaceutical preparations containing them

Publications (2)

Publication Number Publication Date
FI51103B FI51103B (en) 1976-06-30
FI51103C true FI51103C (en) 1976-10-11

Family

ID=27431338

Family Applications (1)

Application Number Title Priority Date Filing Date
FI720497A FI51103C (en) 1971-10-04 1972-02-25 Process for the preparation of anti-inflammatory pregnanoic acid derivatives.

Country Status (18)

Country Link
JP (1) JPS5837320B2 (en)
BE (1) BE779869A (en)
CA (1) CA978518A (en)
CH (2) CH588509A5 (en)
DD (1) DD95565B1 (en)
DK (1) DK136612C (en)
EG (1) EG10635A (en)
FI (1) FI51103C (en)
FR (1) FR2156518B1 (en)
GB (1) GB1387911A (en)
HU (1) HU165261B (en)
IE (1) IE36120B1 (en)
IL (1) IL39735A (en)
LU (1) LU66213A1 (en)
NL (1) NL179059C (en)
NO (1) NO138808C (en)
RO (2) RO70725A (en)
YU (1) YU35148B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK135380C (en) * 1972-12-22 1977-10-03 Schering Ag ANALOGICAL PROCEDURE FOR PREGNAN-21 ACID DERIVATIVES
DE2444618C2 (en) * 1974-09-16 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen New Pregnan-21-Acid-Derivatives
DE2365102C2 (en) * 1973-12-21 1982-12-02 Schering Ag, 1000 Berlin Und 4619 Bergkamen New pregnanic acid derivatives
DE2332663C2 (en) * 1973-06-23 1986-07-31 Schering AG, 1000 Berlin und 4709 Bergkamen Use of corticosteroid active ingredients for inhalation therapy
DE2336438C2 (en) * 1973-07-14 1983-07-07 Schering Ag, 1000 Berlin Und 4619 Bergkamen Process for making 17β-oxalyl steroids
DE2862012D1 (en) * 1978-06-12 1982-10-28 Schering Ag New corticoids, processes for their preparation and pharmaceutical compositions containing them
SE8506015D0 (en) * 1985-12-19 1985-12-19 Draco Ab NOVEL 16,17-ACETALSUBSTITUTED PREGNANE 21-OIC ACID DERIVATIVES
US5215979A (en) * 1985-12-19 1993-06-01 Aktiebolaget Draco 16,17-acetalsubstituted pregnane 21-oic acid derivatives
JP2007237153A (en) * 2006-03-06 2007-09-20 Npo Machinami Ikuseikai Air mixing and agitation technology

Also Published As

Publication number Publication date
FR2156518A1 (en) 1973-06-01
NO138808B (en) 1978-08-07
RO70725A (en) 1982-09-09
RO71183B (en) 1983-07-30
NL7213456A (en) 1973-04-06
YU35148B (en) 1980-09-25
IE36120B1 (en) 1976-08-18
CA978518A (en) 1975-11-25
BE779869A (en) 1972-08-25
IL39735A (en) 1975-08-31
DK136612C (en) 1978-04-10
YU44372A (en) 1980-03-15
NL179059C (en) 1986-07-01
JPS4861464A (en) 1973-08-28
DD95565A5 (en) 1973-02-12
EG10635A (en) 1976-09-30
NL179059B (en) 1986-02-03
FR2156518B1 (en) 1975-06-13
CH589671A5 (en) 1977-07-15
DD95565B1 (en) 1986-10-29
DK136612B (en) 1977-10-31
NO138808C (en) 1978-11-15
HU165261B (en) 1974-07-27
LU66213A1 (en) 1973-01-23
FI51103B (en) 1976-06-30
RO71183A (en) 1983-08-03
CH588509A5 (en) 1977-06-15
IL39735A0 (en) 1972-12-29
JPS5837320B2 (en) 1983-08-15
GB1387911A (en) 1975-03-19
IE36120L (en) 1973-04-04

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