ES339858A1 - Basically substituted oximes of 6,11-dihydro-dibenzo-[b,e]-oxepin- or thiepin-11-ones and their production - Google Patents

Basically substituted oximes of 6,11-dihydro-dibenzo-[b,e]-oxepin- or thiepin-11-ones and their production

Info

Publication number
ES339858A1
ES339858A1 ES339858A ES339858A ES339858A1 ES 339858 A1 ES339858 A1 ES 339858A1 ES 339858 A ES339858 A ES 339858A ES 339858 A ES339858 A ES 339858A ES 339858 A1 ES339858 A1 ES 339858A1
Authority
ES
Spain
Prior art keywords
alkyl
thiepin
oxepin
ones
nr2r3
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES339858A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES339858A1 publication Critical patent/ES339858A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12—[b,e]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/12—[b,e]-condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Novel compounds of the general formula <FORM:1123527/C2/1> (wherein X represents O or S, R1 represents H, halogen, alkyl or alkoxy, A represents a straight or branched C2- 6 alkylene chain, R2 and R3\t each represent H, alkyl or aralkyl or they represent two alkyl groups linked to form a ring, either directly or via an O or S atom or a N atom optionally carrying an alkyl or free or esterified hydroxyalkyl substituent) are prepared from the corresponding 6,11 - dihydrodibenzo - [b,e] - oxepin- or -thiepin-11-ones by (a) reacting them with (aminoalkoxy)-amines H2N-O-A-NR2R3 or acid addition salts thereof, or (b) converting them with hydroxylamine into their oximes, converting these into their alkali metal salts, and reacting the latter with reactive esters of hydroxyalkylamines HO-A-NR2R3. The products may be obtained in the form of, or converted into, pharmacologically acceptable salts with inorganic or organic acids. Pharmaceutical compositions, for oral or parenteral administration in the treatment of psychoses, comprise compounds of the general formula above, or their pharmacologically acceptable acid addition salts, in admixture with pharmaceutically acceptable carrier substances.
ES339858A 1966-03-18 1967-04-27 Basically substituted oximes of 6,11-dihydro-dibenzo-[b,e]-oxepin- or thiepin-11-ones and their production Expired ES339858A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF0048699 1966-03-18

Publications (1)

Publication Number Publication Date
ES339858A1 true ES339858A1 (en) 1968-05-16

Family

ID=7102426

Family Applications (2)

Application Number Title Priority Date Filing Date
ES338208A Expired ES338208A1 (en) 1966-03-18 1967-03-18 Basically substituted oximes of 6,11-dihydro-dibenzo-[b,e]-oxepin- or thiepin-11-ones and their production
ES339858A Expired ES339858A1 (en) 1966-03-18 1967-04-27 Basically substituted oximes of 6,11-dihydro-dibenzo-[b,e]-oxepin- or thiepin-11-ones and their production

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES338208A Expired ES338208A1 (en) 1966-03-18 1967-03-18 Basically substituted oximes of 6,11-dihydro-dibenzo-[b,e]-oxepin- or thiepin-11-ones and their production

Country Status (10)

Country Link
BE (1) BE695653A (en)
CH (1) CH488689A (en)
DE (1) DE1543578C3 (en)
DK (1) DK113021B (en)
ES (2) ES338208A1 (en)
FR (2) FR1514844A (en)
GB (1) GB1123527A (en)
IL (1) IL27537A (en)
NL (1) NL6704075A (en)
SE (1) SE327996B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4003915A (en) * 1970-10-09 1977-01-18 Hoffmann-La Roche Inc. Tricyclic imines

Also Published As

Publication number Publication date
DE1543578C3 (en) 1974-10-10
CH488689A (en) 1970-04-15
SE327996B (en) 1970-09-07
DE1543578B2 (en) 1974-03-14
GB1123527A (en) 1968-08-14
FR6552M (en) 1968-12-16
FR1514844A (en) 1968-02-23
ES338208A1 (en) 1968-04-01
IL27537A (en) 1970-11-30
BE695653A (en) 1967-09-18
DE1543578A1 (en) 1969-09-18
NL6704075A (en) 1967-09-19
DK113021B (en) 1969-02-10

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