ES294657A1 - Improvements in or relating to novel anthracene derivatives - Google Patents
Improvements in or relating to novel anthracene derivativesInfo
- Publication number
- ES294657A1 ES294657A1 ES0294657A ES294657A ES294657A1 ES 294657 A1 ES294657 A1 ES 294657A1 ES 0294657 A ES0294657 A ES 0294657A ES 294657 A ES294657 A ES 294657A ES 294657 A1 ES294657 A1 ES 294657A1
- Authority
- ES
- Spain
- Prior art keywords
- general formula
- prepared
- compound
- mixture
- physiologically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Novel compounds of the general Formula I <FORM:1060466/C2/1> (wherein each of R1 and R2 represents a C1- 4 alkyl or C2- 4 alkenyl radical and R3 represents a C1- 4 alkyl radical), and their acid addition salts, are prepared by splitting off the elements of water from a compound of the general Formula IV <FORM:1060466/C2/2> by the action of a concentrated mineral acid, a strong organic acid, SOCl2, POCl3, ZnCl2 or acetic anhydride, or a mixture thereof (especially a mixture of acetic anhydride and concentrated HCl), and, if desired, converting the product into a salt with an inorganic or organic acid. Substituted 9 - hydroxydihydroanthracenes (IV) are prepared by a Grignard reaction from 10-R1-10-R2-anthrones-(9). Pharmaceutical compositions having antihistaminic, cough inhibiting, bronchodilatory, serotonin inhibiting, anticholinergic and/or sedative properties, for enteral or parenteral administration, comprise a compound of general Formula I, or a physiologically acceptable acid addition salt thereof, and a physiologically acceptable carrier.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1497262A CH419125A (en) | 1962-12-20 | 1962-12-20 | Process for the preparation of new carbocyclic compounds |
CH887863 | 1963-07-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES294657A1 true ES294657A1 (en) | 1964-06-01 |
Family
ID=25703892
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES0294657A Expired ES294657A1 (en) | 1962-12-20 | 1963-12-19 | Improvements in or relating to novel anthracene derivatives |
Country Status (5)
Country | Link |
---|---|
AT (1) | AT243266B (en) |
DE (1) | DE1470259A1 (en) |
DK (1) | DK105025C (en) |
ES (1) | ES294657A1 (en) |
GB (1) | GB1060466A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7736712B2 (en) * | 2002-03-18 | 2010-06-15 | Consort Medical Plc | Seal material for a dispensing apparatus |
-
1963
- 1963-11-27 GB GB4680063A patent/GB1060466A/en not_active Expired
- 1963-12-18 DE DE19631470259 patent/DE1470259A1/en active Pending
- 1963-12-19 ES ES0294657A patent/ES294657A1/en not_active Expired
- 1963-12-19 DK DK594463A patent/DK105025C/en active
- 1963-12-20 AT AT1028063A patent/AT243266B/en active
Also Published As
Publication number | Publication date |
---|---|
AT243266B (en) | 1965-11-10 |
DK105025C (en) | 1966-08-08 |
GB1060466A (en) | 1967-03-01 |
DE1470259A1 (en) | 1969-06-04 |
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