IE40477B1 - Androstane derivatives and compositions containing them - Google Patents
Androstane derivatives and compositions containing themInfo
- Publication number
- IE40477B1 IE40477B1 IE83/75A IE8375A IE40477B1 IE 40477 B1 IE40477 B1 IE 40477B1 IE 83/75 A IE83/75 A IE 83/75A IE 8375 A IE8375 A IE 8375A IE 40477 B1 IE40477 B1 IE 40477B1
- Authority
- IE
- Ireland
- Prior art keywords
- isomer
- androst
- jan
- pure
- compositions containing
- Prior art date
Links
- 150000001440 androstane derivatives Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- ISJVDMWNISUFRJ-HKQXQEGQSA-N (5s,8r,9s,10s,13s,14s)-10,13-dimethyl-1,4,5,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one Chemical compound C1C=CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC[C@H]21 ISJVDMWNISUFRJ-HKQXQEGQSA-N 0.000 abstract 1
- ISJVDMWNISUFRJ-UHFFFAOYSA-N 5alpha-androstan-2-en-17-one Natural products C1C=CCC2(C)C3CCC(C)(C(CC4)=O)C4C3CCC21 ISJVDMWNISUFRJ-UHFFFAOYSA-N 0.000 abstract 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- 239000003810 Jones reagent Substances 0.000 abstract 1
- 230000021736 acetylation Effects 0.000 abstract 1
- 238000006640 acetylation reaction Methods 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal salt Chemical class 0.000 abstract 1
- HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 239000003433 contraceptive agent Substances 0.000 abstract 1
- 230000002254 contraceptive effect Effects 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000002534 ethynyl group Chemical group [H]C#C* 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001817 pituitary effect Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000011369 resultant mixture Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J11/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2211/74A GB1492746A (en) | 1974-01-17 | 1974-01-17 | Androstane derivatives and compositions containing them |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE40477L IE40477L (en) | 1975-07-17 |
| IE40477B1 true IE40477B1 (en) | 1979-06-06 |
Family
ID=9735557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE83/75A IE40477B1 (en) | 1974-01-17 | 1975-01-17 | Androstane derivatives and compositions containing them |
Country Status (19)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3174614D1 (en) * | 1981-06-02 | 1986-06-19 | Theramex | Pharmaceutical compositions containing androstenes |
| JPS60173248A (ja) * | 1984-02-16 | 1985-09-06 | 三晃金属工業株式会社 | 嵌合外囲体 |
| JPS61503032A (ja) * | 1984-08-17 | 1986-12-25 | エス・ア−ル・アイ・インタ−ナシヨナル | 立体異性的に純粋な１７α−エチニル−エストラ−２−エン−１７β−オ−ルおよびその１７β−エステル、製造方法および用途 |
| US5116830A (en) * | 1984-08-17 | 1992-05-26 | Sri International | Stereoisomerically pure 17α-ethynyl-estra-2-en-17β-ol and the 17β esters thereof, methods of preparation and uses |
| DE3661832D1 (en) * | 1985-04-29 | 1989-02-23 | Theramex | Process for the preparation of pure androst-2-ene derivatives |
| FR2598083B1 (fr) * | 1986-05-05 | 1989-12-29 | Theramex Laboratoire | Nouvelles compositions pharmaceutiques a action antiprogesteronique et leur procede d'obtention |
| RU2652702C2 (ru) | 2016-10-19 | 2018-04-28 | Игорь Ву-Юнович Ван | Субатмосферная система теплохолодоснабжения |
-
1974
- 1974-01-17 GB GB2211/74A patent/GB1492746A/en not_active Expired
- 1974-12-18 CH CH1734774A patent/CH606091A5/xx not_active IP Right Cessation
- 1974-12-19 BE BE151716A patent/BE823594A/xx unknown
- 1974-12-30 DK DK690574AA patent/DK135538B/da not_active IP Right Cessation
- 1974-12-31 FR FR7443397A patent/FR2258185B1/fr not_active Expired
-
1975
- 1975-01-09 ES ES433677A patent/ES433677A1/es not_active Expired
- 1975-01-13 DE DE19752501091 patent/DE2501091A1/de active Pending
- 1975-01-14 JP JP698075A patent/JPS576439B2/ja not_active Expired
- 1975-01-14 ZA ZA00750254A patent/ZA75254B/xx unknown
- 1975-01-15 AU AU77335/75A patent/AU521392B2/en not_active Expired
- 1975-01-16 PH PH16719A patent/PH15366A/en unknown
- 1975-01-16 CA CA218,033A patent/CA1065851A/fr not_active Expired
- 1975-01-16 IT IT19319/75A patent/IT1044268B/it active
- 1975-01-16 LU LU71662A patent/LU71662A1/xx unknown
- 1975-01-16 SE SE7500479A patent/SE7500479L/xx unknown
- 1975-01-17 BR BR346/75A patent/BR7500346A/pt unknown
- 1975-01-17 AR AR257331A patent/AR203672A1/es active
- 1975-01-17 NL NLAANVRAGE7500608,A patent/NL183402C/xx not_active IP Right Cessation
- 1975-01-17 IE IE83/75A patent/IE40477B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE823594A (fr) | 1975-04-16 |
| PH15366A (en) | 1982-12-10 |
| DE2501091A1 (de) | 1975-07-24 |
| LU71662A1 (enrdf_load_stackoverflow) | 1975-06-24 |
| ES433677A1 (es) | 1976-11-16 |
| GB1492746A (en) | 1977-11-23 |
| FR2258185B1 (enrdf_load_stackoverflow) | 1978-07-28 |
| IE40477L (en) | 1975-07-17 |
| DK135538B (da) | 1977-05-16 |
| BR7500346A (pt) | 1975-11-04 |
| AU7733575A (en) | 1976-07-15 |
| NL183402C (nl) | 1988-10-17 |
| SE7500479L (enrdf_load_stackoverflow) | 1975-07-18 |
| NL7500608A (nl) | 1975-07-21 |
| IT1044268B (it) | 1980-03-20 |
| CA1065851A (fr) | 1979-11-06 |
| JPS50106952A (enrdf_load_stackoverflow) | 1975-08-22 |
| NL183402B (nl) | 1988-05-16 |
| JPS576439B2 (enrdf_load_stackoverflow) | 1982-02-04 |
| FR2258185A1 (enrdf_load_stackoverflow) | 1975-08-18 |
| AU521392B2 (en) | 1982-04-01 |
| DK135538C (enrdf_load_stackoverflow) | 1977-10-24 |
| DK690574A (enrdf_load_stackoverflow) | 1975-09-29 |
| AR203672A1 (es) | 1975-09-30 |
| CH606091A5 (enrdf_load_stackoverflow) | 1978-10-13 |
| ZA75254B (en) | 1976-01-28 |
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