IE38033B1 - Pyrimidine derivatives and process for preparing the same - Google Patents
Pyrimidine derivatives and process for preparing the sameInfo
- Publication number
- IE38033B1 IE38033B1 IE1093/73A IE109373A IE38033B1 IE 38033 B1 IE38033 B1 IE 38033B1 IE 1093/73 A IE1093/73 A IE 1093/73A IE 109373 A IE109373 A IE 109373A IE 38033 B1 IE38033 B1 IE 38033B1
- Authority
- IE
- Ireland
- Prior art keywords
- formula
- compound
- heptyl
- july
- pyrimidine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
Abstract
1384150 Pyrimidine derivatives LABAZ 12 July 1973 [21 July 1972] 34378/72 Heading C2C The invention comprises compounds of the formula wherein R represents a di- or tri-propylacetyl-, 2 - ethyl - 2 - butyl - acetyl or 2 - methyl - 2- pentyl-acetyl group and R 1 represents H or is selected from the same groups as R; and mono- and di-acid addition salts thereof. They may be obtained by heating a compound of the formula with the appropriate quantity of a compound of the formula wherein R 2 is 2-, 3- or 4-heptyl or 4-(4-propyl)- heptyl and R 3 is Cl or to form the free base of the required compound, which if required may be reacted with a stoichiometric quantity of an organic or inorganic acid to form the corresponding mono- or di-acid addition salts thereof. Examples are given for the production of these compounds. The above compounds possess antiprotozoan activity as well as toxoplasmicidal and antiallergenic properties. They may be administered orally or rectally in the form of coated or uncoated tablets, powders, capsules or suppositories.
[GB1384150A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3437872A GB1384150A (en) | 1972-07-21 | 1972-07-21 | Pyrimidine derivatives and process for preparing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE38033L IE38033L (en) | 1974-01-21 |
| IE38033B1 true IE38033B1 (en) | 1977-12-07 |
Family
ID=10364909
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1093/73A IE38033B1 (en) | 1972-07-21 | 1973-06-29 | Pyrimidine derivatives and process for preparing the same |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS4980082A (en) |
| AR (1) | AR197241A1 (en) |
| AT (1) | AT326671B (en) |
| AU (1) | AU470607B2 (en) |
| BE (1) | BE802451A (en) |
| CA (1) | CA986518A (en) |
| CH (1) | CH579552A5 (en) |
| DE (1) | DE2336678A1 (en) |
| DK (1) | DK131626C (en) |
| ES (1) | ES417142A1 (en) |
| FR (1) | FR2193604B1 (en) |
| GB (1) | GB1384150A (en) |
| HU (1) | HU167313B (en) |
| IE (1) | IE38033B1 (en) |
| NL (1) | NL7309988A (en) |
| NO (1) | NO137691C (en) |
| OA (1) | OA04539A (en) |
| SE (1) | SE399556B (en) |
| SU (1) | SU468422A3 (en) |
| YU (1) | YU180673A (en) |
| ZA (1) | ZA734406B (en) |
-
1972
- 1972-07-21 GB GB3437872A patent/GB1384150A/en not_active Expired
-
1973
- 1973-06-28 ZA ZA734406A patent/ZA734406B/en unknown
- 1973-06-29 IE IE1093/73A patent/IE38033B1/en unknown
- 1973-06-29 AR AR248838A patent/AR197241A1/en active
- 1973-07-02 YU YU01806/73A patent/YU180673A/en unknown
- 1973-07-04 AU AU57699/73A patent/AU470607B2/en not_active Expired
- 1973-07-05 AT AT591673A patent/AT326671B/en not_active IP Right Cessation
- 1973-07-17 BE BE133575A patent/BE802451A/en unknown
- 1973-07-18 NL NL7309988A patent/NL7309988A/xx unknown
- 1973-07-19 DE DE19732336678 patent/DE2336678A1/en active Pending
- 1973-07-19 SE SE7310102A patent/SE399556B/en unknown
- 1973-07-20 CH CH1066673A patent/CH579552A5/xx not_active IP Right Cessation
- 1973-07-20 NO NO2951/73A patent/NO137691C/en unknown
- 1973-07-20 SU SU1939807A patent/SU468422A3/en active
- 1973-07-20 FR FR7326645A patent/FR2193604B1/fr not_active Expired
- 1973-07-20 OA OA54970A patent/OA04539A/en unknown
- 1973-07-20 DK DK404273A patent/DK131626C/en active
- 1973-07-20 HU HULA829A patent/HU167313B/hu unknown
- 1973-07-20 CA CA176990A patent/CA986518A/en not_active Expired
- 1973-07-21 ES ES417142A patent/ES417142A1/en not_active Expired
- 1973-07-21 JP JP48082371A patent/JPS4980082A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NO137691C (en) | 1978-04-05 |
| AU5769973A (en) | 1975-01-09 |
| IE38033L (en) | 1974-01-21 |
| DK131626B (en) | 1975-08-11 |
| OA04539A (en) | 1980-03-30 |
| ES417142A1 (en) | 1976-03-01 |
| YU180673A (en) | 1980-04-30 |
| AT326671B (en) | 1975-12-29 |
| JPS4980082A (en) | 1974-08-02 |
| CH579552A5 (en) | 1976-09-15 |
| AU470607B2 (en) | 1976-03-25 |
| ATA591673A (en) | 1975-03-15 |
| FR2193604A1 (en) | 1974-02-22 |
| NL7309988A (en) | 1974-01-23 |
| CA986518A (en) | 1976-03-30 |
| SU468422A3 (en) | 1975-04-25 |
| NO137691B (en) | 1977-12-27 |
| GB1384150A (en) | 1975-02-19 |
| AR197241A1 (en) | 1974-03-22 |
| ZA734406B (en) | 1974-06-26 |
| DK131626C (en) | 1976-01-19 |
| SE399556B (en) | 1978-02-20 |
| BE802451A (en) | 1974-01-17 |
| DE2336678A1 (en) | 1974-01-31 |
| HU167313B (en) | 1975-09-27 |
| FR2193604B1 (en) | 1977-01-28 |
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