GB1384150A - Pyrimidine derivatives and process for preparing the same - Google Patents

Pyrimidine derivatives and process for preparing the same

Info

Publication number
GB1384150A
GB1384150A GB3437872A GB3437872A GB1384150A GB 1384150 A GB1384150 A GB 1384150A GB 3437872 A GB3437872 A GB 3437872A GB 3437872 A GB3437872 A GB 3437872A GB 1384150 A GB1384150 A GB 1384150A
Authority
GB
United Kingdom
Prior art keywords
formula
compound
heptyl
july
pyrimidine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3437872A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labaz SA
Original Assignee
Labaz SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz SA filed Critical Labaz SA
Priority to GB3437872A priority Critical patent/GB1384150A/en
Priority to ZA734406A priority patent/ZA734406B/en
Priority to IE1093/73A priority patent/IE38033B1/en
Priority to AR248838A priority patent/AR197241A1/en
Priority to YU01806/73A priority patent/YU180673A/en
Priority to AU57699/73A priority patent/AU470607B2/en
Priority to AT591673A priority patent/AT326671B/en
Priority to BE133575A priority patent/BE802451A/en
Priority to NL7309988A priority patent/NL7309988A/xx
Priority to DE19732336678 priority patent/DE2336678A1/en
Priority to SE7310102A priority patent/SE399556B/en
Priority to NO2951/73A priority patent/NO137691C/en
Priority to DK404273A priority patent/DK131626C/en
Priority to FR7326645A priority patent/FR2193604B1/fr
Priority to CA176990A priority patent/CA986518A/en
Priority to HULA829A priority patent/HU167313B/hu
Priority to SU1939807A priority patent/SU468422A3/en
Priority to CH1066673A priority patent/CH579552A5/xx
Priority to OA54970A priority patent/OA04539A/en
Priority to ES417142A priority patent/ES417142A1/en
Priority to JP48082371A priority patent/JPS4980082A/ja
Publication of GB1384150A publication Critical patent/GB1384150A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms

Abstract

1384150 Pyrimidine derivatives LABAZ 12 July 1973 [21 July 1972] 34378/72 Heading C2C The invention comprises compounds of the formula wherein R represents a di- or tri-propylacetyl-, 2 - ethyl - 2 - butyl - acetyl or 2 - methyl - 2- pentyl-acetyl group and R 1 represents H or is selected from the same groups as R; and mono- and di-acid addition salts thereof. They may be obtained by heating a compound of the formula with the appropriate quantity of a compound of the formula wherein R 2 is 2-, 3- or 4-heptyl or 4-(4-propyl)- heptyl and R 3 is Cl or to form the free base of the required compound, which if required may be reacted with a stoichiometric quantity of an organic or inorganic acid to form the corresponding mono- or di-acid addition salts thereof. Examples are given for the production of these compounds. The above compounds possess antiprotozoan activity as well as toxoplasmicidal and antiallergenic properties. They may be administered orally or rectally in the form of coated or uncoated tablets, powders, capsules or suppositories.
GB3437872A 1972-07-21 1972-07-21 Pyrimidine derivatives and process for preparing the same Expired GB1384150A (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
GB3437872A GB1384150A (en) 1972-07-21 1972-07-21 Pyrimidine derivatives and process for preparing the same
ZA734406A ZA734406B (en) 1972-07-21 1973-06-28 Pyrimidine derivatives and process for preparing the same
IE1093/73A IE38033B1 (en) 1972-07-21 1973-06-29 Pyrimidine derivatives and process for preparing the same
AR248838A AR197241A1 (en) 1972-07-21 1973-06-29 A PROCEDURE FOR THE PREPARATION OF NEW PYRIMIDINE DERIVATIVES
YU01806/73A YU180673A (en) 1972-07-21 1973-07-02 Process for preparing novel pyrimidine derivatives
AU57699/73A AU470607B2 (en) 1972-07-21 1973-07-04 Pyrimidine derivatives and process for preparing the same
AT591673A AT326671B (en) 1972-07-21 1973-07-05 PROCESS FOR THE PRODUCTION OF NEW PYRIMIDINE DERIVATIVES AND THEIR SALT
BE133575A BE802451A (en) 1972-07-21 1973-07-17 NEW PYRIMIDINE DERIVATIVES, THEIR PREPARATION PROCESS AND THERAPEUTIC COMPOSITIONS
NL7309988A NL7309988A (en) 1972-07-21 1973-07-18
DE19732336678 DE2336678A1 (en) 1972-07-21 1973-07-19 PYRIDINE DERIVATIVES, PROCESS FOR THEIR MANUFACTURING AND THERAPEUTIC COMPOSITIONS THEREOF
SE7310102A SE399556B (en) 1972-07-21 1973-07-19 WAY TO PRODUCE NEW PYRIMIDINE DERIVATIVES
NO2951/73A NO137691C (en) 1972-07-21 1973-07-20 ANALOGICAL PROCEDURE FOR PREPARING NEW THERAPEUTICALLY ACTIVE PYRIMIDINE DERIVATIVES
DK404273A DK131626C (en) 1972-07-21 1973-07-20 ANALOGICAL PROCEDURE FOR THE PREPARATION OF 2,4-DIAMINO-5-β-CHLOROPHENYL-6-ETHYL-PYRIMIDINE ACYLATE OR ACID ADDITION SALTS THEREOF
FR7326645A FR2193604B1 (en) 1972-07-21 1973-07-20
CA176990A CA986518A (en) 1972-07-21 1973-07-20 Pyrimidine derivatives and process for preparing the same
HULA829A HU167313B (en) 1972-07-21 1973-07-20
SU1939807A SU468422A3 (en) 1972-07-21 1973-07-20 The method of producing pyrimidine derivatives
CH1066673A CH579552A5 (en) 1972-07-21 1973-07-20
OA54970A OA04539A (en) 1972-07-21 1973-07-20 Process for the preparation of new pyrimidine derivatives.
ES417142A ES417142A1 (en) 1972-07-21 1973-07-21 Pyrimidine derivatives and process for preparing the same
JP48082371A JPS4980082A (en) 1972-07-21 1973-07-21

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3437872A GB1384150A (en) 1972-07-21 1972-07-21 Pyrimidine derivatives and process for preparing the same

Publications (1)

Publication Number Publication Date
GB1384150A true GB1384150A (en) 1975-02-19

Family

ID=10364909

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3437872A Expired GB1384150A (en) 1972-07-21 1972-07-21 Pyrimidine derivatives and process for preparing the same

Country Status (21)

Country Link
JP (1) JPS4980082A (en)
AR (1) AR197241A1 (en)
AT (1) AT326671B (en)
AU (1) AU470607B2 (en)
BE (1) BE802451A (en)
CA (1) CA986518A (en)
CH (1) CH579552A5 (en)
DE (1) DE2336678A1 (en)
DK (1) DK131626C (en)
ES (1) ES417142A1 (en)
FR (1) FR2193604B1 (en)
GB (1) GB1384150A (en)
HU (1) HU167313B (en)
IE (1) IE38033B1 (en)
NL (1) NL7309988A (en)
NO (1) NO137691C (en)
OA (1) OA04539A (en)
SE (1) SE399556B (en)
SU (1) SU468422A3 (en)
YU (1) YU180673A (en)
ZA (1) ZA734406B (en)

Also Published As

Publication number Publication date
NO137691C (en) 1978-04-05
AU5769973A (en) 1975-01-09
IE38033B1 (en) 1977-12-07
IE38033L (en) 1974-01-21
DK131626B (en) 1975-08-11
OA04539A (en) 1980-03-30
ES417142A1 (en) 1976-03-01
YU180673A (en) 1980-04-30
AT326671B (en) 1975-12-29
JPS4980082A (en) 1974-08-02
CH579552A5 (en) 1976-09-15
AU470607B2 (en) 1976-03-25
ATA591673A (en) 1975-03-15
FR2193604A1 (en) 1974-02-22
NL7309988A (en) 1974-01-23
CA986518A (en) 1976-03-30
SU468422A3 (en) 1975-04-25
NO137691B (en) 1977-12-27
AR197241A1 (en) 1974-03-22
ZA734406B (en) 1974-06-26
DK131626C (en) 1976-01-19
SE399556B (en) 1978-02-20
BE802451A (en) 1974-01-17
DE2336678A1 (en) 1974-01-31
HU167313B (en) 1975-09-27
FR2193604B1 (en) 1977-01-28

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee