ES351003A1 - Novel iminodibenzyl derivatives and a process for the manufacture thereof - Google Patents

Novel iminodibenzyl derivatives and a process for the manufacture thereof

Info

Publication number
ES351003A1
ES351003A1 ES351003A ES351003A ES351003A1 ES 351003 A1 ES351003 A1 ES 351003A1 ES 351003 A ES351003 A ES 351003A ES 351003 A ES351003 A ES 351003A ES 351003 A1 ES351003 A1 ES 351003A1
Authority
ES
Spain
Prior art keywords
acid addition
addition salt
formula
novel
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES351003A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES351003A1 publication Critical patent/ES351003A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

The invention comprises compounds of the formula wherein R represents a straight chain C 1 -C 4 alkyl group, and acid addition salts thereof. They may be obtained by reacting N-amino-2,8- dimethyl-iminobenzyl or an acid addition salt thereof with a ketone of the formula or an acid addition salt thereof and treating the reaction product with an acidic cyclization agent if necessary and, if required, converting the resulting acid addition salt into the free base or a different acid addition salt. Examples are given for the production of the compounds. Pharmaceutical compositions for enteral or parenteral administration comprise a compound of the invention together with a compatible pharmaceutical carrier. The compositions which have antiserotinin and depressant activity and are useful as sedatives and tranquillizers may be in the form of tablets, pills, powders, granules, emulsions, suspensions or solutions.
ES351003A 1967-02-28 1968-02-27 Novel iminodibenzyl derivatives and a process for the manufacture thereof Expired ES351003A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB953767A GB1149507A (en) 1967-02-28 1967-02-28 Novel iminodibenzyl derivatives and a process for the manufacture thereof

Publications (1)

Publication Number Publication Date
ES351003A1 true ES351003A1 (en) 1969-05-16

Family

ID=9873912

Family Applications (1)

Application Number Title Priority Date Filing Date
ES351003A Expired ES351003A1 (en) 1967-02-28 1968-02-27 Novel iminodibenzyl derivatives and a process for the manufacture thereof

Country Status (7)

Country Link
AT (1) AT277254B (en)
BE (1) BE710986A (en)
DE (1) DE1695222A1 (en)
ES (1) ES351003A1 (en)
FR (2) FR7379M (en)
GB (2) GB1149507A (en)
NL (1) NL6801795A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3829431A (en) * 1972-04-19 1974-08-13 Endo Lab Process for the preparation of certain indolobenzazepine derivatives
US6930183B2 (en) 2003-04-17 2005-08-16 Crompton Corporation Alkylated iminodibenzyls as antioxidants

Also Published As

Publication number Publication date
NL6801795A (en) 1968-08-29
DE1695222A1 (en) 1971-03-18
AT277254B (en) 1969-12-29
GB1149508A (en) 1969-04-23
FR1574728A (en) 1969-07-18
FR7379M (en) 1969-10-27
BE710986A (en) 1968-07-01
GB1149507A (en) 1969-04-23

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