ES417142A1 - Pyrimidine derivatives and process for preparing the same - Google Patents

Pyrimidine derivatives and process for preparing the same

Info

Publication number
ES417142A1
ES417142A1 ES417142A ES417142A ES417142A1 ES 417142 A1 ES417142 A1 ES 417142A1 ES 417142 A ES417142 A ES 417142A ES 417142 A ES417142 A ES 417142A ES 417142 A1 ES417142 A1 ES 417142A1
Authority
ES
Spain
Prior art keywords
formula
heptyl
acetyl
derivatives
see formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES417142A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labaz SA
Original Assignee
Labaz SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz SA filed Critical Labaz SA
Publication of ES417142A1 publication Critical patent/ES417142A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Procedure for obtaining pyrimidine derivatives, of general formula: **(See formula)** and of the pharmaceutically acceptable single (mono) and double (di) acid addition salts of these derivatives, where R represents a dipropylacetyl, tripropylacetyl, 2-ethylbutyl-acetyl- or 2-methyl-2-pentyl-acetyl group y represents hydrogen or a dipropylacetyl, tripropylacetyl, 2-ethyl-2-butyl-acetyl or 2-methyl-pentyl-acetyl group, characterized in that 2,4-diamino-5-p-chlorophenyl-6-ethyl- is heated pyrimidine, formula **(See formula)** with the appropriate amount of a compound of the general formula: **(See formula)** where it represents a 2-heptyl, 3-heptyl, 4-heptyl or 4- (4-propyl) -heptyl group and R6 represents a chlorine atom or **(See formula)** where R5 has the same meaning as formula II, to form the necessary mono- or di-substituted derivatives of formula I in the form of a free base which, if desired, can be reacted with a stoichiometric amount of an organic or inorganic acid to form a single or double addition, pharmaceutically acceptable acid salt. (Machine-translation by Google Translate, not legally binding)
ES417142A 1972-07-21 1973-07-21 Pyrimidine derivatives and process for preparing the same Expired ES417142A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3437872A GB1384150A (en) 1972-07-21 1972-07-21 Pyrimidine derivatives and process for preparing the same

Publications (1)

Publication Number Publication Date
ES417142A1 true ES417142A1 (en) 1976-03-01

Family

ID=10364909

Family Applications (1)

Application Number Title Priority Date Filing Date
ES417142A Expired ES417142A1 (en) 1972-07-21 1973-07-21 Pyrimidine derivatives and process for preparing the same

Country Status (21)

Country Link
JP (1) JPS4980082A (en)
AR (1) AR197241A1 (en)
AT (1) AT326671B (en)
AU (1) AU470607B2 (en)
BE (1) BE802451A (en)
CA (1) CA986518A (en)
CH (1) CH579552A5 (en)
DE (1) DE2336678A1 (en)
DK (1) DK131626C (en)
ES (1) ES417142A1 (en)
FR (1) FR2193604B1 (en)
GB (1) GB1384150A (en)
HU (1) HU167313B (en)
IE (1) IE38033B1 (en)
NL (1) NL7309988A (en)
NO (1) NO137691C (en)
OA (1) OA04539A (en)
SE (1) SE399556B (en)
SU (1) SU468422A3 (en)
YU (1) YU180673A (en)
ZA (1) ZA734406B (en)

Also Published As

Publication number Publication date
NL7309988A (en) 1974-01-23
SE399556B (en) 1978-02-20
NO137691B (en) 1977-12-27
YU180673A (en) 1980-04-30
HU167313B (en) 1975-09-27
DE2336678A1 (en) 1974-01-31
FR2193604A1 (en) 1974-02-22
CH579552A5 (en) 1976-09-15
JPS4980082A (en) 1974-08-02
NO137691C (en) 1978-04-05
ATA591673A (en) 1975-03-15
AR197241A1 (en) 1974-03-22
DK131626C (en) 1976-01-19
CA986518A (en) 1976-03-30
IE38033B1 (en) 1977-12-07
ZA734406B (en) 1974-06-26
IE38033L (en) 1974-01-21
AT326671B (en) 1975-12-29
OA04539A (en) 1980-03-30
AU470607B2 (en) 1976-03-25
SU468422A3 (en) 1975-04-25
AU5769973A (en) 1975-01-09
BE802451A (en) 1974-01-17
FR2193604B1 (en) 1977-01-28
DK131626B (en) 1975-08-11
GB1384150A (en) 1975-02-19

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