ES408184A1 - 15-hydroxy vincamine - Google Patents
15-hydroxy vincamineInfo
- Publication number
- ES408184A1 ES408184A1 ES408184A ES408184A ES408184A1 ES 408184 A1 ES408184 A1 ES 408184A1 ES 408184 A ES408184 A ES 408184A ES 408184 A ES408184 A ES 408184A ES 408184 A1 ES408184 A1 ES 408184A1
- Authority
- ES
- Spain
- Prior art keywords
- salts
- group
- apovincamine
- alkali metal
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A process for the preparation of alkaloids of the eburnamine type of the general formula (I) **(See formula)** or the salts of these compounds, where R1 represents a hydrogen atom or a hydroxy group, R2 represents a carboxy group or a C1-6 alkoxycarbonyl group, and R3 represents a hydroxy group or an alkoxy group in which apovincamine is reacted to) with an alkali metal alcoholate, or b) with an alkali metal permanganate, in order to saturate the double bond at position Δ 16,17 of apovincamine, and if desired, the obtained compound is separated, optionally converted into their acid addition salts or quaternary salts and, if desired, the salts are converted to free bases or other salts. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HURI455A HU166474B (en) | 1971-11-03 | 1971-11-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES408184A1 true ES408184A1 (en) | 1975-11-01 |
Family
ID=11000881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES408184A Expired ES408184A1 (en) | 1971-11-03 | 1972-11-02 | 15-hydroxy vincamine |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS515400B2 (en) |
| AR (1) | AR196498A1 (en) |
| AT (2) | AT318823B (en) |
| AU (1) | AU470084B2 (en) |
| BE (1) | BE790842A (en) |
| BG (2) | BG20379A3 (en) |
| CA (1) | CA982585A (en) |
| CH (2) | CH586702A5 (en) |
| DD (1) | DD101405A5 (en) |
| DE (1) | DE2253778A1 (en) |
| EG (1) | EG10720A (en) |
| ES (1) | ES408184A1 (en) |
| FR (1) | FR2158371B1 (en) |
| GB (1) | GB1402085A (en) |
| HU (1) | HU166474B (en) |
| IL (1) | IL40623A (en) |
| NL (1) | NL7214768A (en) |
| NO (1) | NO136198C (en) |
| PL (1) | PL71069B1 (en) |
| RO (2) | RO62345A (en) |
| SE (1) | SE7508516L (en) |
| ZA (1) | ZA727382B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU532001B2 (en) * | 1978-11-20 | 1983-09-15 | Sumitomo Chemical Company, Limited | Polycyclic indole derivatives |
| US4316028A (en) * | 1978-11-20 | 1982-02-16 | Sumitomo Chemical Company, Limited | Process for producing eburnane derivatives |
| HU187139B (en) * | 1982-06-30 | 1985-11-28 | Richter Gedeon Vegyeszet | Process for preparing new eburnan derivatives |
-
1971
- 1971-11-03 HU HURI455A patent/HU166474B/hu unknown
-
1972
- 1972-10-16 CA CA153,943A patent/CA982585A/en not_active Expired
- 1972-10-16 CH CH1510372A patent/CH586702A5/xx not_active IP Right Cessation
- 1972-10-16 CH CH1320575A patent/CH577504A5/xx not_active IP Right Cessation
- 1972-10-17 ZA ZA727382A patent/ZA727382B/en unknown
- 1972-10-17 NO NO3716/72A patent/NO136198C/en unknown
- 1972-10-19 BG BG23693A patent/BG20379A3/xx unknown
- 1972-10-19 IL IL40623A patent/IL40623A/en unknown
- 1972-10-19 BG BG21668A patent/BG20601A3/xx unknown
- 1972-10-20 AU AU47984/72A patent/AU470084B2/en not_active Expired
- 1972-10-21 EG EG440/72A patent/EG10720A/en active
- 1972-10-25 AT AT910372A patent/AT318823B/en not_active IP Right Cessation
- 1972-10-25 AT AT978773*7A patent/AT328624B/en not_active IP Right Cessation
- 1972-10-31 BE BE790842D patent/BE790842A/en unknown
- 1972-10-31 DD DD166591A patent/DD101405A5/xx unknown
- 1972-10-31 FR FR7238529A patent/FR2158371B1/fr not_active Expired
- 1972-11-01 JP JP47108965A patent/JPS515400B2/ja not_active Expired
- 1972-11-01 NL NL7214768A patent/NL7214768A/xx unknown
- 1972-11-02 AR AR244942A patent/AR196498A1/en active
- 1972-11-02 PL PL1972158592A patent/PL71069B1/en unknown
- 1972-11-02 GB GB810074A patent/GB1402085A/en not_active Expired
- 1972-11-02 ES ES408184A patent/ES408184A1/en not_active Expired
- 1972-11-02 DE DE2253778A patent/DE2253778A1/en active Pending
- 1972-11-03 RO RO72721A patent/RO62345A/ro unknown
- 1972-11-03 RO RO7200080514A patent/RO63053A/en unknown
-
1975
- 1975-07-25 SE SE7508516A patent/SE7508516L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SU438183A3 (en) | 1974-07-30 |
| CH577504A5 (en) | 1976-07-15 |
| JPS515400B2 (en) | 1976-02-19 |
| AR196498A1 (en) | 1974-02-06 |
| BG20601A3 (en) | 1975-12-05 |
| RO62345A (en) | 1977-08-15 |
| EG10720A (en) | 1976-07-31 |
| FR2158371B1 (en) | 1975-08-08 |
| AT328624B (en) | 1976-03-25 |
| IL40623A0 (en) | 1972-12-29 |
| CH586702A5 (en) | 1977-04-15 |
| GB1402085A (en) | 1975-08-06 |
| ZA727382B (en) | 1973-06-27 |
| DD101405A5 (en) | 1973-11-05 |
| IL40623A (en) | 1975-12-31 |
| PL71069B1 (en) | 1974-04-30 |
| CA982585A (en) | 1976-01-27 |
| FR2158371A1 (en) | 1973-06-15 |
| NO136198C (en) | 1977-08-03 |
| NL7214768A (en) | 1973-05-07 |
| HU166474B (en) | 1975-03-28 |
| RO63053A (en) | 1978-05-15 |
| BE790842A (en) | 1973-02-15 |
| ATA978773A (en) | 1975-06-15 |
| AU470084B2 (en) | 1976-03-04 |
| AU4798472A (en) | 1974-04-26 |
| NO136198B (en) | 1977-04-25 |
| AT318823B (en) | 1974-11-25 |
| BG20379A3 (en) | 1975-11-05 |
| SE7508516L (en) | 1975-07-25 |
| DE2253778A1 (en) | 1973-05-10 |
| JPS4852800A (en) | 1973-07-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES267248A1 (en) | Pyrazolo-pyrimidines and process for preparing same | |
| ES438946A2 (en) | Vincaminic acid esters | |
| ES425626A1 (en) | Acylxylidide local anaesthetics | |
| ES409190A1 (en) | Citric acid derivatives | |
| ES408184A1 (en) | 15-hydroxy vincamine | |
| ES403486A1 (en) | Procedure for the preparation of piperazine derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES418422A1 (en) | 21-substituted 17-aza-steroids and salts thereof | |
| ES325827A1 (en) | Procedure to produce 2-phenoxy-2-phenylacetamide compounds. (Machine-translation by Google Translate, not legally binding) | |
| ES454005A1 (en) | Triazole derivatives and processes for the production thereof | |
| ES390275A1 (en) | A procedure for the preparation of 1,2-dialquil (lower) pirrolydines. (Machine-translation by Google Translate, not legally binding) | |
| ES403388A1 (en) | A procedure for the production of oxofurilic esters. (Machine-translation by Google Translate, not legally binding) | |
| ES392355A1 (en) | D-homosteroid imides and a process for the preparation thereof | |
| ES341697A1 (en) | Procedure for the production of new dihidro-1-piridil-isoquinoleinas. (Machine-translation by Google Translate, not legally binding) | |
| ES428011A1 (en) | Procedure for the preparation of 2-amino-3,5-dibromobencilamina. (Machine-translation by Google Translate, not legally binding) | |
| ES402551A1 (en) | A procedure for the preparation of piperazine derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES377994A1 (en) | Procedure for the preparation of new derivatives of imidazolidinone. (Machine-translation by Google Translate, not legally binding) | |
| ES228018A1 (en) | A method of production of N-oxides of amino-terciary alcohols (Machine-translation by Google Translate, not legally binding) | |
| ES403689A3 (en) | Procedure for the preparation of tieno (2,3-e) - (1,4) - diazepin-2-onas. (Machine-translation by Google Translate, not legally binding) | |
| GB1034677A (en) | New alkaloids and processes for their production | |
| ES366913A1 (en) | A procedure for the preparation of therapeutically active substitute cyclohexanes. (Machine-translation by Google Translate, not legally binding) | |
| ES389369A1 (en) | Procedure for the production of piperidil - replaced furanones. (Machine-translation by Google Translate, not legally binding) | |
| ES421341A1 (en) | Di-hydroxygenzenesulphonic acid salts | |
| ES444540A1 (en) | Process for the preparation of 1,4-naphthodinitrile | |
| GB835860A (en) | A method of producing pharmaceutically active tropinyl ethers | |
| ES395971A1 (en) | Thiolcarbamates |