IE35980L - Modified double-stranded rna - Google Patents
Modified double-stranded rnaInfo
- Publication number
- IE35980L IE35980L IE720053A IE5372A IE35980L IE 35980 L IE35980 L IE 35980L IE 720053 A IE720053 A IE 720053A IE 5372 A IE5372 A IE 5372A IE 35980 L IE35980 L IE 35980L
- Authority
- IE
- Ireland
- Prior art keywords
- rna
- natural
- jan
- stranded rna
- modified double
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1356263 Antiviral compositions containing modified double stranded RNA BEECHAM GROUP Ltd 11 Jan 1972 [14 Jan 1971] 1940/71 Heading A5B [Also in Division C3] A pharmaceutical composition useful generally in the prophylaxis of viral infections comprises a modified form of a natural ds. RNA having antiviral activity and a reduced acute toxicity relative to the normal form of ds. RNA from the same natural source which is obtained by (a) treating the natural form of ds. RNA with an alkali metal hydroxide at a pH between 11.0 and 12.5 in an aqueous electrolyte solution, under conditions of temperature, time and electrolyte concentration such that partial separation of the polynucleotide strands of each ds. RNA molecule commences immediately and no more than 25 phosphate di-ester linkages per strand are hydrolysed during the period of the reaction and then (b) neutralising the resultant solution. Detailed physical chemical and medicinal properties are given.
[GB1356263A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB194071A GB1356263A (en) | 1971-01-14 | 1971-01-14 | Modified double-stranded rna |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE35980L true IE35980L (en) | 1972-07-14 |
| IE35980B1 IE35980B1 (en) | 1976-07-21 |
Family
ID=9730714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE53/72A IE35980B1 (en) | 1971-01-14 | 1972-01-14 | Modified double-stranded rna |
Country Status (13)
| Country | Link |
|---|---|
| AT (1) | AT340604B (en) |
| AU (1) | AU3796472A (en) |
| BE (1) | BE778102A (en) |
| CA (1) | CA966830A (en) |
| CH (1) | CH568760A5 (en) |
| DE (1) | DE2201513A1 (en) |
| DK (1) | DK129709B (en) |
| FR (1) | FR2121772B1 (en) |
| GB (1) | GB1356263A (en) |
| IE (1) | IE35980B1 (en) |
| NL (1) | NL7200481A (en) |
| SE (1) | SE386450B (en) |
| ZA (1) | ZA72169B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2353293A1 (en) * | 1976-06-03 | 1977-12-30 | Beljanski Mirko | POLYRIBONUCLEOTIDES WITH AN ACTIVITY IN THE GENESIS OF LEUCOCYTES AND BLOOD PLATELETS |
-
1971
- 1971-01-14 GB GB194071A patent/GB1356263A/en not_active Expired
-
1972
- 1972-01-10 CA CA132,060A patent/CA966830A/en not_active Expired
- 1972-01-11 ZA ZA720169A patent/ZA72169B/en unknown
- 1972-01-12 AT AT22572A patent/AT340604B/en not_active IP Right Cessation
- 1972-01-12 NL NL7200481A patent/NL7200481A/xx not_active Application Discontinuation
- 1972-01-12 FR FR7200892A patent/FR2121772B1/fr not_active Expired
- 1972-01-13 CH CH45772A patent/CH568760A5/xx not_active IP Right Cessation
- 1972-01-13 SE SE7200373A patent/SE386450B/en unknown
- 1972-01-13 DE DE19722201513 patent/DE2201513A1/en active Pending
- 1972-01-14 BE BE778102A patent/BE778102A/en unknown
- 1972-01-14 AU AU37964/72A patent/AU3796472A/en not_active Expired
- 1972-01-14 DK DK20072AA patent/DK129709B/en unknown
- 1972-01-14 IE IE53/72A patent/IE35980B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2121772A1 (en) | 1972-08-25 |
| DK129709C (en) | 1975-04-21 |
| GB1356263A (en) | 1974-06-12 |
| FR2121772B1 (en) | 1975-08-01 |
| SE386450B (en) | 1976-08-09 |
| IE35980B1 (en) | 1976-07-21 |
| CA966830A (en) | 1975-04-29 |
| ZA72169B (en) | 1972-09-27 |
| DE2201513A1 (en) | 1972-07-27 |
| NL7200481A (en) | 1972-07-18 |
| BE778102A (en) | 1972-07-14 |
| AT340604B (en) | 1977-12-27 |
| CH568760A5 (en) | 1975-11-14 |
| DK129709B (en) | 1974-11-11 |
| ATA22572A (en) | 1977-04-15 |
| AU3796472A (en) | 1973-07-19 |
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