IE34046B1 - New azepine derivative, its preparation and composition containing it - Google Patents
New azepine derivative, its preparation and composition containing itInfo
- Publication number
- IE34046B1 IE34046B1 IE302/70A IE30270A IE34046B1 IE 34046 B1 IE34046 B1 IE 34046B1 IE 302/70 A IE302/70 A IE 302/70A IE 30270 A IE30270 A IE 30270A IE 34046 B1 IE34046 B1 IE 34046B1
- Authority
- IE
- Ireland
- Prior art keywords
- preparation
- composition containing
- azepine derivative
- new azepine
- new
- Prior art date
Links
- 150000001538 azepines Chemical class 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000994 depressogenic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- CTRLABGOLIVAIY-UHFFFAOYSA-N oxcarbazepine Chemical compound C1C(=O)C2=CC=CC=C2N(C(=O)N)C2=CC=CC=C21 CTRLABGOLIVAIY-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 206010044652 trigeminal neuralgia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
- C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH358369A CH500196A (de) | 1969-03-10 | 1969-03-10 | Verfahren zur Herstellung von neuen Azepinderivaten |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE34046L IE34046L (en) | 1970-09-10 |
| IE34046B1 true IE34046B1 (en) | 1975-01-08 |
Family
ID=4259115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE302/70A IE34046B1 (en) | 1969-03-10 | 1970-03-09 | New azepine derivative, its preparation and composition containing it |
Country Status (24)
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI75561C (fi) * | 1979-10-30 | 1988-07-11 | Ciba Geigy Ag | Foerfarande foer framstaellning av 5- karbamoyl-10-oxo-10,11-dihydro-5h-dibens/b,f/azepin och daertill noedvaendiga mellanprodukter. |
| EP0108715A1 (de) * | 1982-10-15 | 1984-05-16 | Ciba-Geigy Ag | Dibenzazepincarboxamide |
| FR2700117B1 (fr) * | 1993-01-07 | 1995-02-03 | Rhone Poulenc Rorer Sa | Application d'anticonvulsivants dans le traitement de la maladie de Parkinson et des syndromes parkinsoniens. |
| US5472714A (en) * | 1993-09-08 | 1995-12-05 | Ciba-Geigy Corporation | Double-layered oxcarbazepine tablets |
| IT1272897B (it) * | 1995-01-13 | 1997-07-01 | I F C Iniziative Finanziaarie | Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide |
| PT101732B (pt) * | 1995-06-30 | 1997-12-31 | Portela & Ca Sa | Novas di-hidrodibenzo<b,f>azepinas substituidas processo para a sua preparacao composicoes farmaceuticas que as contem e utilizacao dos novos compostos na preparacao de composicoes farmaceuticas empregues em doencas do sistema nervoso |
| PT101876B (pt) * | 1996-05-27 | 1999-09-30 | Portela & Ca Sa | Novos derivados de 10,11-di-hidro-10-oxo-5h-dibenzo(b,f)azepina-5-carboxamida |
| US20020022056A1 (en) * | 1997-02-14 | 2002-02-21 | Burkhard Schlutermann | Oxacarbazepine film-coated tablets |
| AT406957B (de) * | 1998-11-25 | 2000-11-27 | Dsm Fine Chem Austria Gmbh | Verfahren zur oxidation von methyl-, methylen- oder methingruppen enthaltenden substraten |
| ATE224347T1 (de) | 1998-11-25 | 2002-10-15 | Dsm Fine Chem Austria Gmbh | Verfahren zur oxidation von methyl-, methylen- oder methingruppen enthaltenden substraten |
| GB9930058D0 (en) | 1999-12-20 | 2000-02-09 | Novartis Ag | Organic compounds |
| IT1317854B1 (it) * | 2000-02-25 | 2003-07-15 | Farchemia Srl | 5-ciano-10-idrossi-10,11-diidro-5h-dibenz(b,f)azepina e procedimentiper la sua preparazione e per la sua conversione in |
| CA2437402A1 (en) * | 2001-02-12 | 2002-08-22 | Teva Pharmaceutical Industries, Ltd. | New crystal forms of oxcarbazepine and processes for their preparation |
| TW200501962A (en) * | 2003-04-01 | 2005-01-16 | Novartis Ag | Use of carbamazepine derivatives for the treatment of agitation in dementia patients |
| MXPA06002392A (es) | 2003-09-03 | 2006-06-20 | Novartis Ag | Uso de oxcarbazepina para el tratamiento de dolor neuropatico diabetico y la mejora del sueno. |
| EP1678140A2 (en) * | 2003-10-20 | 2006-07-12 | Amoli Organics Ltd. | Novel process for preparation of 10-oxo-10, 11-dihydro-5h-dibenz [b,f]azepine-5-carboxamide (oxcarbazepine) via intermediate, 10-methoxy-5h-dibenz [b,f] azepine-5-carbonylchloride |
| ITMI20040452A1 (it) * | 2004-03-09 | 2004-06-09 | Clariant Lsm Italia Spa | Processo per la preparazione di oxcarbazepina |
| US7459553B2 (en) * | 2004-03-11 | 2008-12-02 | Glenmark Generics Ltd. | Process for the preparation of carboxamide compounds |
| WO2005096709A2 (en) * | 2004-03-11 | 2005-10-20 | Sun Pharmaceutical Industries Limited | A process for the preparation of 10,11-dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide |
| EP1600443A1 (en) * | 2004-05-26 | 2005-11-30 | Alberto Milanese | Process for the preparation of oxcarbazepine |
| CA2471666C (en) * | 2004-06-18 | 2009-10-13 | Apotex Pharmachem Inc. | An improved process for the preparation of oxcarbazepine and related intermediates |
| US20060252745A1 (en) * | 2005-05-06 | 2006-11-09 | Almeida Jose L D | Methods of preparing pharmaceutical compositions comprising eslicarbazepine acetate and methods of use |
| EP2026815B1 (en) | 2006-04-26 | 2011-01-26 | Supernus Pharmaceuticals, Inc. | Controlled released preparations of oxcarbazepine having sigmoidal release profile |
| GB0700773D0 (en) | 2007-01-15 | 2007-02-21 | Portela & Ca Sa | Drug therapies |
| US20090082335A1 (en) * | 2007-09-26 | 2009-03-26 | Protia, Llc | Deuterium-enriched oxcarbazepine |
| AU2008331868B2 (en) | 2007-11-28 | 2015-02-12 | Nektar Therapeutics | Oligomer-tricyclic conjugates |
| US8530647B2 (en) * | 2008-05-08 | 2013-09-10 | Mylan Laboratories Limited | Process for the preparation of oxcarbazepine |
| WO2011091050A1 (en) | 2010-01-19 | 2011-07-28 | Nektar Therapeutics | Oligomer-tricyclic conjugates |
| US20150232426A1 (en) | 2012-09-26 | 2015-08-20 | Ranbaxy Laboratories Limited | Process for the preparation of oxcarbazepine and its use as intermediate in the preparation of eslicarbazepine acetate |
| MX2018008021A (es) | 2015-12-30 | 2018-11-09 | Adamas Pharmaceuticals Inc | Metodos y composiciones para el tratamiento de trastornos relacionados con convulsiones. |
| MX388586B (es) | 2016-12-16 | 2025-03-20 | Idorsia Pharmaceuticals Ltd | Combinacion farmaceutica que comprende un bloqueador del canal de calcio de tipo t. |
| US10639313B2 (en) | 2017-09-01 | 2020-05-05 | Ndsu Research Foundation | Compound for inhibition of delta-5-desaturase (D5D) and treatment of cancer and inflammation |
| AU2019348194B2 (en) | 2018-09-28 | 2025-04-03 | Griffith University | Agents and methods for modulating pathogen activity |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH403767A (de) * | 1961-06-09 | 1965-12-15 | Geigy Ag J R | Verfahren zur Herstellung von neuen N-heterocyclischen Verbindungen |
-
1969
- 1969-03-10 CH CH358369A patent/CH500196A/de not_active IP Right Cessation
-
1970
- 1970-03-03 NL NL7003022.A patent/NL162904C/xx not_active IP Right Cessation
- 1970-03-03 NO NO00756/70*[A patent/NO130314B/no unknown
- 1970-03-03 FI FI700559A patent/FI50523C/fi active
- 1970-03-03 DK DK104570AA patent/DK125649B/da not_active IP Right Cessation
- 1970-03-03 SE SE02770/70A patent/SE349301B/xx unknown
- 1970-03-04 US US16552A patent/US3642775A/en not_active Expired - Lifetime
- 1970-03-05 YU YU536/70A patent/YU33862B/xx unknown
- 1970-03-09 BR BR217332/70A patent/BR7017332D0/pt unknown
- 1970-03-09 CA CA076787A patent/CA920586A/en not_active Expired
- 1970-03-09 CS CS155670A patent/CS154294B2/cs unknown
- 1970-03-09 DE DE2011087A patent/DE2011087C3/de not_active Expired
- 1970-03-09 AT AT218770A patent/AT298492B/de not_active IP Right Cessation
- 1970-03-09 ES ES377279A patent/ES377279A1/es not_active Expired
- 1970-03-09 FR FR707008344A patent/FR2034781B1/fr not_active Expired
- 1970-03-09 BG BG014133A patent/BG17576A3/xx unknown
- 1970-03-09 BE BE747085D patent/BE747085A/xx not_active IP Right Cessation
- 1970-03-09 GB GB1111070A patent/GB1310571A/en not_active Expired
- 1970-03-09 PL PL1970139290A patent/PL80549B1/pl unknown
- 1970-03-09 IE IE302/70A patent/IE34046B1/xx unknown
- 1970-03-09 IL IL34026A patent/IL34026A/en unknown
-
1971
- 1971-09-20 US US00182213A patent/US3716640A/en not_active Expired - Lifetime
-
1976
- 1976-05-31 KE KE2635*UA patent/KE2635A/xx unknown
- 1976-08-19 HK HK519/76*UA patent/HK51976A/xx unknown
- 1976-12-30 MY MY194/76A patent/MY7600194A/xx unknown
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