IE32158B1 - Substituted anthranilic acid amides - Google Patents
Substituted anthranilic acid amidesInfo
- Publication number
- IE32158B1 IE32158B1 IE74768A IE74768A IE32158B1 IE 32158 B1 IE32158 B1 IE 32158B1 IE 74768 A IE74768 A IE 74768A IE 74768 A IE74768 A IE 74768A IE 32158 B1 IE32158 B1 IE 32158B1
- Authority
- IE
- Ireland
- Prior art keywords
- acid amides
- anthranilic acid
- substituted anthranilic
- pref
- alkyl
- Prior art date
Links
- PXBFMLJZNCDSMP-UHFFFAOYSA-N 2-Aminobenzamide Chemical class NC(=O)C1=CC=CC=C1N PXBFMLJZNCDSMP-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- OROGSEYTTFOCAN-DNJOTXNNSA-N codeine Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC OROGSEYTTFOCAN-DNJOTXNNSA-N 0.000 abstract 2
- 241000699670 Mus sp. Species 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 229960004126 codeine Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 230000003533 narcotic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
- C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK342267A DK121236B (da) | 1967-07-03 | 1967-07-03 | Analogifremgangsmåde til fremstilling af terapeutisk aktive, basisk substituerede amider af N-substituerede antranilsyrer, eller syreadditionssalte deraf. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE32158L IE32158L (en) | 1969-01-03 |
| IE32158B1 true IE32158B1 (en) | 1973-05-02 |
Family
ID=8122684
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE74768A IE32158B1 (en) | 1967-07-03 | 1968-06-24 | Substituted anthranilic acid amides |
Country Status (13)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090238763A1 (en) | 2006-07-09 | 2009-09-24 | Chongxi Yu | High penetration compositions and uses thereof |
| US20090221703A1 (en) | 2006-07-09 | 2009-09-03 | Chongxi Yu | High penetration composition and uses thereof |
| PL2623495T3 (pl) * | 2006-09-03 | 2019-11-29 | Techfields Biochem Co Ltd | Dodatnio naładowane rozpuszczalne w wodzie proleki kwasów n-aryloantranilowych o bardzo dużej szybkości przenikania przez skórę |
| CN101687792B (zh) | 2007-06-04 | 2016-03-02 | 于崇曦 | 具有快速皮肤和生物膜穿透速度的非甾体抗炎药的前药及其医药用途 |
| KR20210123406A (ko) | 2008-12-04 | 2021-10-13 | 충시 위 | 고투과력을 가진 조성물 및 이의 적용 |
| HK1207562A1 (en) | 2012-01-18 | 2016-02-05 | 苏州泰飞尔医药有限公司 | High penetration prodrug compositions and pharmaceutical composition thereof for treatment of pulmonary conditions |
| JP6153264B2 (ja) * | 2015-01-05 | 2017-06-28 | テックフィールズ インコーポレイテッド | 非常に速い皮膚及び膜浸透速度を有するｎｓａｉａプロドラッグ及びその新規医薬使用 |
-
1967
- 1967-07-03 DK DK342267A patent/DK121236B/da not_active IP Right Cessation
-
1968
- 1968-06-24 IE IE74768A patent/IE32158B1/xx unknown
- 1968-06-25 GB GB3033568A patent/GB1165300A/en not_active Expired
- 1968-07-02 ES ES355674A patent/ES355674A1/es not_active Expired
- 1968-07-02 NO NO265268A patent/NO121213B/no unknown
- 1968-07-02 BR BR20033268A patent/BR6800332D0/pt unknown
- 1968-07-02 CH CH989768A patent/CH512436A/de not_active IP Right Cessation
- 1968-07-02 FR FR1584334D patent/FR1584334A/fr not_active Expired
- 1968-07-02 NL NL6809321A patent/NL163503C/xx active
- 1968-07-03 BE BE717543D patent/BE717543A/xx unknown
- 1968-07-03 CA CA024135A patent/CA921051A/en not_active Expired
- 1968-07-03 SE SE918268A patent/SE363504B/xx unknown
- 1968-07-03 FI FI191768A patent/FI49024C/fi active
Also Published As
| Publication number | Publication date |
|---|---|
| BE717543A (enrdf_load_stackoverflow) | 1968-12-16 |
| GB1165300A (en) | 1969-09-24 |
| NL163503B (nl) | 1980-04-15 |
| NL163503C (nl) | 1980-09-15 |
| NL6809321A (enrdf_load_stackoverflow) | 1969-01-07 |
| DE1768818B2 (de) | 1977-05-05 |
| FR1584334A (enrdf_load_stackoverflow) | 1969-12-19 |
| SE363504B (enrdf_load_stackoverflow) | 1974-01-21 |
| DK121236B (da) | 1971-09-27 |
| BR6800332D0 (pt) | 1973-02-13 |
| DE1768818A1 (de) | 1971-12-30 |
| NO121213B (enrdf_load_stackoverflow) | 1971-02-01 |
| ES355674A1 (es) | 1970-01-01 |
| FI49024C (fi) | 1975-03-10 |
| CA921051A (en) | 1973-02-13 |
| FI49024B (enrdf_load_stackoverflow) | 1974-12-02 |
| CH512436A (de) | 1971-09-15 |
| IE32158L (en) | 1969-01-03 |
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