IE32158L - Anthranilic acid amides - Google Patents

Anthranilic acid amides

Info

Publication number
IE32158L
IE32158L IE74768A IE74768A IE32158L IE 32158 L IE32158 L IE 32158L IE 74768 A IE74768 A IE 74768A IE 74768 A IE74768 A IE 74768A IE 32158 L IE32158 L IE 32158L
Authority
IE
Ireland
Prior art keywords
acid amides
anthranilic acid
pref
alkyl
ch512436a
Prior art date
Application number
IE74768A
Other versions
IE32158B1 (en
Original Assignee
Gea As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gea As filed Critical Gea As
Publication of IE32158L publication Critical patent/IE32158L/en
Publication of IE32158B1 publication Critical patent/IE32158B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Cpds. of general formula (I) and their salts. R1 = H, 1-5 C alkyl (pref. Me) R2 = 2-5 C alkylene (pref. C2H4, C3H6) R3R4 = Me2, Et2 or MeEt R5,6 = H, 1-5 C alkyl, halogen, CF3; both is not = H and not para to NH As analgesics of low toxicity. No antipyretic or Straub effect in mice. As active as codeine, but not narcotic. [CH512436A]
IE74768A 1967-07-03 1968-06-24 Substituted anthranilic acid amides IE32158B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK342267A DK121236B (en) 1967-07-03 1967-07-03 Analogous process for the preparation of therapeutically active, basic substituted amides of N-substituted anthranilic acids, or acid addition salts thereof.

Publications (2)

Publication Number Publication Date
IE32158L true IE32158L (en) 1969-01-03
IE32158B1 IE32158B1 (en) 1973-05-02

Family

ID=8122684

Family Applications (1)

Application Number Title Priority Date Filing Date
IE74768A IE32158B1 (en) 1967-07-03 1968-06-24 Substituted anthranilic acid amides

Country Status (13)

Country Link
BE (1) BE717543A (en)
BR (1) BR6800332D0 (en)
CA (1) CA921051A (en)
CH (1) CH512436A (en)
DK (1) DK121236B (en)
ES (1) ES355674A1 (en)
FI (1) FI49024C (en)
FR (1) FR1584334A (en)
GB (1) GB1165300A (en)
IE (1) IE32158B1 (en)
NL (1) NL163503C (en)
NO (1) NO121213B (en)
SE (1) SE363504B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
EP2084132B1 (en) * 2006-09-03 2018-08-08 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of n-arylanthranilic acids with very fast skin penetration rate
PL2170826T3 (en) * 2007-06-04 2022-09-05 Techfields Inc Pro-drugs of nsaias with very high skin and membranes penetration rates and their new medicinal uses
CA3213470A1 (en) 2008-12-04 2010-06-10 Chongxi Yu High penetration compositions and their applications
CA3189252A1 (en) 2012-05-16 2013-11-21 Techfields Pharma Co., Ltd. High penetration prodrug compositions and pharmaceutical composition thereof for treatment of pulmonary conditions
JP6153264B2 (en) * 2015-01-05 2017-06-28 テックフィールズ インコーポレイテッド NSAIA prodrug with very fast skin and membrane permeation rate and novel pharmaceutical use thereof

Also Published As

Publication number Publication date
NL6809321A (en) 1969-01-07
BE717543A (en) 1968-12-16
DK121236B (en) 1971-09-27
FR1584334A (en) 1969-12-19
IE32158B1 (en) 1973-05-02
CA921051A (en) 1973-02-13
ES355674A1 (en) 1970-01-01
FI49024C (en) 1975-03-10
DE1768818B2 (en) 1977-05-05
CH512436A (en) 1971-09-15
BR6800332D0 (en) 1973-02-13
NO121213B (en) 1971-02-01
GB1165300A (en) 1969-09-24
SE363504B (en) 1974-01-21
FI49024B (en) 1974-12-02
NL163503B (en) 1980-04-15
DE1768818A1 (en) 1971-12-30
NL163503C (en) 1980-09-15

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