ID30037A - Metoda untuk mereduksi tingkat serum trigliserida dan untuk menghambat angiogenesis menggunakan asam-asam indolalkanoat tersubstitusi - Google Patents

Metoda untuk mereduksi tingkat serum trigliserida dan untuk menghambat angiogenesis menggunakan asam-asam indolalkanoat tersubstitusi

Info

Publication number
ID30037A
ID30037A IDW00200101404A ID20011404A ID30037A ID 30037 A ID30037 A ID 30037A ID W00200101404 A IDW00200101404 A ID W00200101404A ID 20011404 A ID20011404 A ID 20011404A ID 30037 A ID30037 A ID 30037A
Authority
ID
Indonesia
Prior art keywords
trigliceridal
indolalicanic
acids
substituted
methods
Prior art date
Application number
IDW00200101404A
Other languages
English (en)
Inventor
Janet Sredy
Jorge Jacot
Original Assignee
Inst For Pharm Discovery Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst For Pharm Discovery Inc filed Critical Inst For Pharm Discovery Inc
Publication of ID30037A publication Critical patent/ID30037A/id

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/428Thiazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IDW00200101404A 1998-12-01 1999-12-01 Metoda untuk mereduksi tingkat serum trigliserida dan untuk menghambat angiogenesis menggunakan asam-asam indolalkanoat tersubstitusi ID30037A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11039598P 1998-12-01 1998-12-01

Publications (1)

Publication Number Publication Date
ID30037A true ID30037A (id) 2001-11-01

Family

ID=22332786

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW00200101404A ID30037A (id) 1998-12-01 1999-12-01 Metoda untuk mereduksi tingkat serum trigliserida dan untuk menghambat angiogenesis menggunakan asam-asam indolalkanoat tersubstitusi

Country Status (30)

Country Link
US (5) US6555568B1 (id)
EP (1) EP1135124B1 (id)
JP (1) JP2002531398A (id)
KR (1) KR20010086075A (id)
CN (1) CN1368883A (id)
AP (1) AP2001002146A0 (id)
AT (1) ATE265210T1 (id)
AU (1) AU770925B2 (id)
BG (1) BG105531A (id)
BR (1) BR9915882A (id)
CA (1) CA2385845A1 (id)
CZ (1) CZ20011864A3 (id)
DE (1) DE69916881T2 (id)
DZ (1) DZ2953A1 (id)
EE (1) EE200100296A (id)
HK (1) HK1046372A1 (id)
HU (1) HUP0104953A3 (id)
ID (1) ID30037A (id)
IL (1) IL143247A0 (id)
MX (1) MXPA02003118A (id)
NO (1) NO20012690L (id)
OA (1) OA12035A (id)
PL (1) PL349016A1 (id)
SK (1) SK7352001A3 (id)
TN (1) TNSN99224A1 (id)
TR (1) TR200101539T2 (id)
TW (1) TW584560B (id)
WO (1) WO2000032180A2 (id)
YU (1) YU40101A (id)
ZA (1) ZA200104126B (id)

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PL2046740T3 (pl) 2006-07-22 2012-10-31 Oxagen Ltd Związki o aktywności antagonisty CRTH2
PE20090159A1 (es) * 2007-03-08 2009-02-21 Plexxikon Inc COMPUESTOS DERIVADOS DE ACIDO INDOL-PROPIONICO COMO MODULADORES PPARs
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TNSN99224A1 (fr) * 1998-12-01 2005-11-10 Inst For Pharm Discovery Inc Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
WO2001064205A2 (en) * 2000-03-02 2001-09-07 The Institutes For Pharmaceutical Discovery, Llc Compositions containing a substituted indolealkanoic acid and an angiotensin converting enzyme inhibitor

Also Published As

Publication number Publication date
BR9915882A (pt) 2001-08-21
MXPA02003118A (es) 2004-04-21
SK7352001A3 (en) 2002-06-04
EE200100296A (et) 2003-02-17
AU770925B2 (en) 2004-03-11
US20100324105A1 (en) 2010-12-23
HUP0104953A2 (hu) 2002-07-29
US6964980B2 (en) 2005-11-15
DE69916881D1 (de) 2004-06-03
CA2385845A1 (en) 2000-06-08
WO2000032180A2 (en) 2000-06-08
ZA200104126B (en) 2002-05-21
IL143247A0 (en) 2002-04-21
US20060074114A1 (en) 2006-04-06
HK1046372A1 (zh) 2003-01-10
CN1368883A (zh) 2002-09-11
PL349016A1 (en) 2002-06-17
AU2161600A (en) 2000-06-19
DZ2953A1 (fr) 2004-03-15
DE69916881T2 (de) 2005-02-03
KR20010086075A (ko) 2001-09-07
HUP0104953A3 (en) 2002-08-28
BG105531A (en) 2001-12-31
CZ20011864A3 (cs) 2002-03-13
JP2002531398A (ja) 2002-09-24
TR200101539T2 (tr) 2001-12-21
EP1135124B1 (en) 2004-04-28
ATE265210T1 (de) 2004-05-15
US6555568B1 (en) 2003-04-29
TW584560B (en) 2004-04-21
WO2000032180A3 (en) 2000-11-16
AP2001002146A0 (en) 2001-06-30
NO20012690L (no) 2001-07-27
US20030216452A1 (en) 2003-11-20
NO20012690D0 (no) 2001-05-31
TNSN99224A1 (fr) 2005-11-10
YU40101A (sh) 2005-07-19
EP1135124A2 (en) 2001-09-26
OA12035A (en) 2006-05-02
US20120065203A1 (en) 2012-03-15

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