ID27153A - Senyawa inhibitor spla2 untuk mengobati penyakit - Google Patents

Senyawa inhibitor spla2 untuk mengobati penyakit

Info

Publication number
ID27153A
ID27153A IDW20002214A ID20002214A ID27153A ID 27153 A ID27153 A ID 27153A ID W20002214 A IDW20002214 A ID W20002214A ID 20002214 A ID20002214 A ID 20002214A ID 27153 A ID27153 A ID 27153A
Authority
ID
Indonesia
Prior art keywords
inhibitor compounds
treat disease
spla2 inhibitor
spla2
treat
Prior art date
Application number
IDW20002214A
Other languages
English (en)
Indonesian (id)
Inventor
William Louis Macias
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ID27153A publication Critical patent/ID27153A/id

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/22Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IDW20002214A 1998-05-01 1999-04-20 Senyawa inhibitor spla2 untuk mengobati penyakit ID27153A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8387498P 1998-05-01 1998-05-01

Publications (1)

Publication Number Publication Date
ID27153A true ID27153A (id) 2001-03-08

Family

ID=22181224

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20002214A ID27153A (id) 1998-05-01 1999-04-20 Senyawa inhibitor spla2 untuk mengobati penyakit

Country Status (20)

Country Link
US (1) US6340699B1 (hr)
EP (1) EP1084108A4 (hr)
JP (1) JP2002513783A (hr)
KR (1) KR20010043190A (hr)
CN (1) CN1299348A (hr)
AU (1) AU3656299A (hr)
BR (1) BR9910095A (hr)
CA (1) CA2330856A1 (hr)
CZ (1) CZ20004052A3 (hr)
EA (1) EA200001140A1 (hr)
HR (1) HRP20000739A2 (hr)
HU (1) HUP0102243A2 (hr)
ID (1) ID27153A (hr)
IL (1) IL139019A0 (hr)
NO (1) NO20005479L (hr)
PL (1) PL343708A1 (hr)
SK (1) SK16342000A3 (hr)
TR (1) TR200003194T2 (hr)
WO (1) WO1999057100A1 (hr)
ZA (1) ZA200005563B (hr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19962300A1 (de) * 1999-12-23 2001-06-28 Asta Medica Ag Substituierte N-Benzyl-Indol-3-yl-glyoxylsäure-Derivate mit Antitumorwirkung
WO2001055108A2 (en) * 2000-01-25 2001-08-02 Eli Lilly And Company Use of spl a2 inhibitors for the treatment of inflammation
WO2002000621A1 (fr) * 2000-06-29 2002-01-03 Shionogi & Co., Ltd. Composes inhibiteurs de la spla2 de type x
CZ2003176A3 (cs) * 2000-07-24 2003-06-18 Dov Global Technologies Inc. Prostředky z termoplastického superabsorpčního polymerního blendu a jejich příprava
US20090318492A1 (en) * 2005-11-03 2009-12-24 Han-Ting Chang Indole compounds having c4-acidic substituents and use thereof as phospholipase-a2 inhibitors
JPWO2009123080A1 (ja) * 2008-04-01 2011-07-28 アステラス製薬株式会社 インドリノン化合物
CN102413825A (zh) 2009-04-29 2012-04-11 阿马里纳股份公司 含有epa和心血管剂的药物组合物以及使用其的方法
US9290752B2 (en) 2013-03-13 2016-03-22 Sunny Delight Beverages Co. Process for enhancing the amylase inhibitory efficacy from phaseolus vulgaris extracts

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356919A (en) 1991-05-30 1994-10-18 G. D. Searle & Co. Leukotriene B4 synthesis inhibitors
DE4218096A1 (de) 1992-06-02 1993-12-09 Boehringer Mannheim Gmbh Spiro-oxetane, Verfahren zu ihrer Herstellung und Arzneimittel
DE4323409A1 (de) 1993-07-13 1995-01-19 Boehringer Mannheim Gmbh Verwendung von Cumarinen und Carbostyrilen als PLA¶2¶-Inhibitoren, neue Cumarine und Carbostyrile, Verfahren zu ihrer Herstellung und Arzneimittel
DE69527322T2 (de) 1994-04-01 2003-02-27 Eli Lilly And Co., Indianapolis 1H-Indol-3-Glyoxylamid sPLA2 Inhibitoren
WO1995033462A1 (en) * 1994-06-02 1995-12-14 Smithkline Beecham Corporation Anti-inflammatory compounds
NZ298145A (en) * 1994-12-29 1998-08-26 Yamanouchi Pharma Co Ltd Monoclonal antibodies having inhibitory effect on type ii phospholipase a2, proteins forming part thereof, cells producing them, dna encoding them, recombinant vector comprising the dna and medicament
NZ335246A (en) 1996-10-30 2001-09-28 Lilly Co Eli Substituted carbazole or hydrogenated carbazole derivatives; useful for inhibiting sPLA2 (human non-pancreatic secretory phospholipase A2) mediated release of fatty acids for conditions such as septic shock
GEP20032920B (en) * 1998-02-25 2003-03-25 Genetics Inst Inhibitors of Phospholipase Enzymes

Also Published As

Publication number Publication date
NO20005479D0 (no) 2000-10-31
CA2330856A1 (en) 1999-11-11
KR20010043190A (ko) 2001-05-25
BR9910095A (pt) 2000-12-26
CZ20004052A3 (cs) 2002-05-15
US6340699B1 (en) 2002-01-22
AU3656299A (en) 1999-11-23
CN1299348A (zh) 2001-06-13
PL343708A1 (en) 2001-08-27
HRP20000739A2 (en) 2001-10-31
JP2002513783A (ja) 2002-05-14
NO20005479L (no) 2000-12-20
SK16342000A3 (sk) 2002-04-04
IL139019A0 (en) 2001-11-25
EA200001140A1 (ru) 2001-04-23
TR200003194T2 (tr) 2001-03-21
EP1084108A1 (en) 2001-03-21
EP1084108A4 (en) 2005-01-12
ZA200005563B (en) 2002-01-10
WO1999057100A1 (en) 1999-11-11
HUP0102243A2 (hu) 2001-10-28

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