ID25620A - Turunan-turunan asam karboksilat baru, pembuatannya dan penggunaannya sebagai campuran reseptor antagonis et a/et b - Google Patents

Turunan-turunan asam karboksilat baru, pembuatannya dan penggunaannya sebagai campuran reseptor antagonis et a/et b

Info

Publication number
ID25620A
ID25620A IDW20000386D ID20000386D ID25620A ID 25620 A ID25620 A ID 25620A ID W20000386 D IDW20000386 D ID W20000386D ID 20000386 D ID20000386 D ID 20000386D ID 25620 A ID25620 A ID 25620A
Authority
ID
Indonesia
Prior art keywords
carboxicate
antagonical
receptors
mixture
new
Prior art date
Application number
IDW20000386D
Other languages
English (en)
Indonesian (id)
Inventor
Wilhelm Amberg
Rolf Jansen
Dagmar Klinge
Harmut Richers
Stefan Hargenroder
Manfred Raschack
Liliane Unger
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19738578A external-priority patent/DE19738578A1/de
Priority claimed from DE1998111915 external-priority patent/DE19811915A1/de
Application filed by Basf Ag filed Critical Basf Ag
Publication of ID25620A publication Critical patent/ID25620A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70One oxygen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/34One oxygen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/36One oxygen atom
    • C07D263/38One oxygen atom attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
IDW20000386D 1997-09-04 1998-08-24 Turunan-turunan asam karboksilat baru, pembuatannya dan penggunaannya sebagai campuran reseptor antagonis et a/et b ID25620A (id)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19738578A DE19738578A1 (de) 1997-09-04 1997-09-04 Neue Carbonsäurederivate, ihre Herstellung und Verwendung als gemischte ET¶A¶/ET¶B¶-Rezeptorantagonisten
DE1998111915 DE19811915A1 (de) 1998-03-18 1998-03-18 Neue Carbonsäurederivate, ihre Herstellung und Verwendung als gemischte ET¶A¶/ET¶B¶-Rezeptorantagonisten
PCT/EP1998/005354 WO1999011629A1 (de) 1997-09-04 1998-08-24 Neue carbonsäurederivate, ihre herstellung und verwendung als gemischte eta/etb-endothelin-rezeptorantagonisten

Publications (1)

Publication Number Publication Date
ID25620A true ID25620A (id) 2000-10-19

Family

ID=26039663

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20000386D ID25620A (id) 1997-09-04 1998-08-24 Turunan-turunan asam karboksilat baru, pembuatannya dan penggunaannya sebagai campuran reseptor antagonis et a/et b

Country Status (21)

Country Link
EP (1) EP1009741A1 (pt)
JP (1) JP2001514254A (pt)
KR (1) KR20010023615A (pt)
CN (1) CN1269792A (pt)
AR (1) AR017052A1 (pt)
AU (1) AU748610B2 (pt)
BG (1) BG104222A (pt)
BR (1) BR9811631A (pt)
CA (1) CA2302350A1 (pt)
CO (1) CO4970738A1 (pt)
HR (1) HRP980484A2 (pt)
HU (1) HUP0004935A3 (pt)
ID (1) ID25620A (pt)
IL (1) IL134276A0 (pt)
NO (1) NO20001077L (pt)
NZ (1) NZ502660A (pt)
PL (1) PL338954A1 (pt)
SK (1) SK1522000A3 (pt)
TR (1) TR200000602T2 (pt)
TW (1) TW546295B (pt)
WO (1) WO1999011629A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19924892A1 (de) * 1999-06-01 2000-12-07 Basf Ag Neue Carbonsäurederivate mit arylsubstituierten Stickstoffheterocyclen, ihre Herstellung und Verwendung als Endothelin Rezeptorantagonisten
EP2021324B1 (en) * 2006-05-29 2011-12-14 NicOx S.A. Nitrated heterocyclic compounds as endothelin receptor antagonist
DK2268644T3 (da) 2008-03-05 2011-10-10 Boehringer Ingelheim Int Tricycliske pyridinderivater, medikamenter indeholdende sådanne forbindelser, deres anvendelse og fremgangsmåde til deres fremstilling
ES2462065T3 (es) * 2009-07-10 2014-05-22 Cadila Healthcare Limited Proceso mejorado para la preparación de Ambrisentán e intermedios novedosos de este
US20120053197A1 (en) 2010-02-19 2012-03-01 Boehringer Ingelheim International Gmbh Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation
AR087577A1 (es) 2011-08-17 2014-04-03 Boehringer Ingelheim Int Derivados de furo[3,4-c]quinolina, medicamentos que contienen dichos compuestos, su uso y proceso para su preparacion

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4411225A1 (de) * 1994-03-31 1995-10-05 Basf Ag Verwendung von Carbonsäurederivaten als Arzneimittel
DE19533023B4 (de) * 1994-10-14 2007-05-16 Basf Ag Neue Carbonsäurederivate, ihre Herstellung und Verwendung
JP2000504013A (ja) * 1996-02-01 2000-04-04 スミスクライン・ビーチャム・コーポレイション エンドセリンレセプターアンタゴニスト
DE19614542A1 (de) * 1996-04-12 1997-10-16 Basf Ag Neue Carbonsäurederivate, ihre Herstellung und Verwendung
DE19636046A1 (de) * 1996-09-05 1998-03-12 Basf Ag Neue Carbonsäurederivate, ihre Herstellung und Verwendung als gemischte ET¶A¶/ET¶B¶-Rezeptorantagonisten

Also Published As

Publication number Publication date
AU9533398A (en) 1999-03-22
HUP0004935A3 (en) 2001-12-28
CN1269792A (zh) 2000-10-11
IL134276A0 (en) 2001-04-30
JP2001514254A (ja) 2001-09-11
EP1009741A1 (de) 2000-06-21
HRP980484A2 (en) 1999-06-30
NO20001077D0 (no) 2000-03-02
NO20001077L (no) 2000-03-02
BR9811631A (pt) 2000-09-26
AR017052A1 (es) 2001-08-22
NZ502660A (en) 2002-02-01
CO4970738A1 (es) 2000-11-07
KR20010023615A (ko) 2001-03-26
BG104222A (en) 2001-02-28
AU748610B2 (en) 2002-06-06
PL338954A1 (en) 2000-12-04
HUP0004935A2 (hu) 2001-10-28
TW546295B (en) 2003-08-11
CA2302350A1 (en) 1999-03-11
TR200000602T2 (tr) 2000-12-21
SK1522000A3 (en) 2000-08-14
WO1999011629A1 (de) 1999-03-11

Similar Documents

Publication Publication Date Title
ID19417A (id) TURUNAN-TURUNAN ASAM KARBOKSILAT BARU, PEMBUATAN DAN PEMAKAIANNYA SEBAGAI ANTAGONIS RESEPTOR ET a/ET b TERCAMPUR
ID26420A (id) Indolinon-indolinon tersubstitusi baru, pembuatannya dan penggunaannya sebagai komposisi-komposisi farmasi
ID26305A (id) Benzamida tersubstitusi baru, pembuatan dan penggunaannya
ID18613A (id) Oksadiazol baru, proses pembuatannya serta penggunaannya sebagai komposisi farmasi
ID26207A (id) ESTRATRIENA TERSUBSTITUSI 11β-HALOGEN-7 αTERSUBSTITUTASI, PROSES UNTUK MEMPRODUKSI SEDIAAN FARMASI YANG MENGANDUNG ESTRATRIENA 11β-HALOGEN-7 αINI DAN JUGA PENGGUNAANNYA UNTUK PRODUKSI ZAT-ZAT FARMASI
ID22821A (id) Turunan sulfonamida, proses pembuatannya dan penggunaannya sebagai obat
ID26248A (id) Turunan asiguanidina baru sebagai inhibitor penyerapan tulang dan sebagai antagonis reseptor vitronektin
ID22528A (id) Komposisi farmasi fenofibrat yang memiliki biovabilitas tinggi dan metoda pembuatannya
DE69822186D1 (de) Herstellung von mustern
ID27558A (id) Amida-amida aromatik baru, metode pembuatannya dan penggunaannya sebagai obat
BR9801606B1 (pt) composto, processo para sua preparação, substáncia farmacêutica, uso do composto e processo para a produção de uma substáncia farmacêutica.
NO994003L (no) Farmasoytisk blanding
ID21393A (id) Asam benzazepinon-n-asetat tersubstitusi-asam fosfonat, proses pembuatan dan obat-obat yang mengandung senyawa ini
FI954007A0 (fi) Substituoitujen 4-fenyyli-6-amino-nikotiinihappojohdannaisten käyttö lääkeaineena
ID25591A (id) Senyawa-senyawa asam meta-azasiklik amino benzoat dan turunan-turunannya yang merupakan antagonis integrin
ID20855A (id) Senyawa turunan imidazolidin baru, pembuatannya, penggunaannya dan sediaan farmasi yang mengandung senyawa tersebut
DE59809971D1 (de) Herstellung von granularem sekundärem alkansulfonat
ID25620A (id) Turunan-turunan asam karboksilat baru, pembuatannya dan penggunaannya sebagai campuran reseptor antagonis et a/et b
ID24278A (id) Turunan-turunan asam karboksilat baru dengan rantai sisi amida, pembuatan dan penggunaannya sebagai reseptor antagonis endotelin
ID30484A (id) Turunan 4-heterosikliksulfonamidil 6 metoksi 5 (2 metoksi fenoksi) 2 piridil-pirimidin, pembuatannya dan penggunaan sebagai antagonis reseptor endotelin
ID19050A (id) Turunan-turunan asam karboksilat yang baru, pembuatannya dan penggunaannya
PT1015433E (pt) 1,2,3,4,5,6-hexa-hidro-2,6-metano-3-benzazocin-10-ois substituidos processo para a sua producao e sua utilizacao como medicamentos
ID24283A (id) Turunan-turunan asam karboksilat baru, pembuatannya dan penggunaannya dalam pengobatan kanker
ID24346A (id) Turunan asam karboksilat betha -amino dan betha -azido baru, pembuatan dan penggunaannya sebagai antagonis reseptor andotelin
ID22756A (id) Proses untuk membuat secara kontinyu suatu campuran berair e-kaprolaktam dan prekursor-prekursor ekaprolaktam