ID24878A - Turunan ariltiazolidinedion - Google Patents
Turunan ariltiazolidinedionInfo
- Publication number
- ID24878A ID24878A IDW20001163A ID20001163A ID24878A ID 24878 A ID24878 A ID 24878A ID W20001163 A IDW20001163 A ID W20001163A ID 20001163 A ID20001163 A ID 20001163A ID 24878 A ID24878 A ID 24878A
- Authority
- ID
- Indonesia
- Prior art keywords
- ariltiazolidinedion
- ppar
- thiazolidinediones
- hypertriglyceridemia
- hyperglycemia
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 208000035150 Hypercholesterolemia Diseases 0.000 abstract 1
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 108010028924 PPAR alpha Proteins 0.000 abstract 1
- 102000023984 PPAR alpha Human genes 0.000 abstract 1
- 108010015181 PPAR delta Proteins 0.000 abstract 1
- 108010016731 PPAR gamma Proteins 0.000 abstract 1
- 102000003728 Peroxisome Proliferator-Activated Receptors Human genes 0.000 abstract 1
- 108090000029 Peroxisome Proliferator-Activated Receptors Proteins 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 201000001421 hyperglycemia Diseases 0.000 abstract 1
- 208000006575 hypertriglyceridemia Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 208000037803 restenosis Diseases 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/44—Two oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6827197P | 1997-12-19 | 1997-12-19 | |
| GBGB9816279.5A GB9816279D0 (en) | 1998-07-27 | 1998-07-27 | Arylthiazolidinedione derivatives |
| US10523898P | 1998-10-22 | 1998-10-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID24878A true ID24878A (id) | 2000-08-31 |
Family
ID=27269416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW20001163A ID24878A (id) | 1997-12-19 | 1998-12-18 | Turunan ariltiazolidinedion |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1040102B1 (es) |
| JP (1) | JP3373198B2 (es) |
| KR (1) | KR20010033355A (es) |
| CN (1) | CN1282325A (es) |
| AT (1) | ATE352545T1 (es) |
| AU (1) | AU740733B2 (es) |
| BG (1) | BG104602A (es) |
| BR (1) | BR9813801A (es) |
| CA (1) | CA2315397C (es) |
| DE (1) | DE69836980T2 (es) |
| EA (1) | EA200000687A1 (es) |
| ES (1) | ES2281146T3 (es) |
| HU (1) | HUP0101366A2 (es) |
| ID (1) | ID24878A (es) |
| IL (1) | IL136138A0 (es) |
| IS (1) | IS5506A (es) |
| NO (1) | NO20003112L (es) |
| PL (1) | PL340958A1 (es) |
| SK (1) | SK9212000A3 (es) |
| TR (1) | TR200001753T2 (es) |
| WO (1) | WO1999032465A1 (es) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9824614D0 (en) | 1998-11-11 | 1999-01-06 | Glaxo Group Ltd | Chemical compounds |
| DE60035639T2 (de) * | 1999-05-20 | 2008-05-21 | Ciba Specialty Chemicals Holding Inc. | Hydroxydiphenyletherverbindungen |
| CA2376919C (en) * | 1999-06-18 | 2008-11-04 | Merck & Co., Inc. | Arylthiazolidinedione and aryloxazolidinedione derivatives |
| AU5876900A (en) * | 1999-06-18 | 2001-01-09 | Merck & Co., Inc. | Process for making arylthiazolidinedione derivatives |
| US7041691B1 (en) | 1999-06-30 | 2006-05-09 | Amgen Inc. | Compounds for the modulation of PPARγ activity |
| DK1206457T3 (da) * | 1999-08-27 | 2004-02-16 | Lilly Co Eli | Biaryl-oxa(thia)zolderivater og deres anvendelse som modulatorer PPAP'ER |
| EP1304121A4 (en) * | 1999-11-10 | 2004-06-23 | Takeda Chemical Industries Ltd | INHIBITORS OF BODY WEIGHT GAIN |
| US20030171399A1 (en) | 2000-06-28 | 2003-09-11 | Tularik Inc. | Quinolinyl and benzothiazolyl modulators |
| AU2001298065A1 (en) * | 2001-01-12 | 2003-09-02 | Abbott Laboratories | Process for the preparation of matrix metalloproteinase inhibitors |
| ATE480236T1 (de) * | 2001-04-25 | 2010-09-15 | Takeda Pharmaceutical | Verwendung des abc-expressionspromotors pioglitazon zur behandlung von arteriosklerose obliterans |
| WO2004011448A1 (en) * | 2002-07-25 | 2004-02-05 | Merck & Co., Inc. | Therapeutic compounds for treating dyslipidemic conditions |
| CN100475810C (zh) * | 2002-08-30 | 2009-04-08 | 霍夫曼-拉罗奇有限公司 | 作为PPARα和PPARγ激动剂的新型2-芳基噻唑化合物 |
| ATE425966T1 (de) * | 2002-11-26 | 2009-04-15 | Pfizer Prod Inc | Durch phenyl subtituierten piperidinverbindungen zur verwendung als ppar-aktivatoren |
| CN1319956C (zh) * | 2003-09-12 | 2007-06-06 | 深圳市海粤门生物科技开发有限公司 | 一种噻唑烷二酮的衍生物及其药用制剂的制备方法和应用 |
| EP2100877B1 (en) * | 2003-09-19 | 2012-01-25 | Janssen Pharmaceutica N.V. | 4-((Phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
| HUE028213T2 (en) * | 2003-09-19 | 2016-12-28 | Janssen Pharmaceutica Nv | 4 - ((Phenoxyalkyl) thio) -phenoxyacetic acid for use in the treatment of PPAR-delta-mediated conditions |
| WO2005070905A1 (en) * | 2004-01-20 | 2005-08-04 | Merck & Co., Inc. | Antidiabetic oxazolidinediones and thiazolidinediones |
| WO2006138328A1 (en) * | 2005-06-14 | 2006-12-28 | Merck & Co., Inc. | Process for the production of antidiabetic oxazolidinediones |
| AU2006269503A1 (en) | 2005-07-06 | 2007-01-18 | Merck & Co., Inc. | Antidiabetic oxazolidinediones and thiazolidinediones |
| JP2009502783A (ja) * | 2005-07-20 | 2009-01-29 | メルク エンド カムパニー インコーポレーテッド | 抗糖尿病性オキサゾリジンジオン及びチアゾリジンジオン |
| CA2963784A1 (en) | 2007-06-08 | 2008-12-18 | Mannkind Corporation | Ire-1.alpha. inhibitors |
| CN105001174A (zh) * | 2015-07-14 | 2015-10-28 | 佛山市赛维斯医药科技有限公司 | 含苯并异恶唑和末端腈基苄基类结构的化合物及其用途 |
| CN104987314A (zh) * | 2015-07-14 | 2015-10-21 | 佛山市赛维斯医药科技有限公司 | 含苯并异恶唑和末端硝基苄基类结构的化合物及其用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3053490B2 (ja) * | 1991-02-25 | 2000-06-19 | 杏林製薬株式会社 | チアゾリジン−２，４−ジオン誘導体とその塩及び製造法 |
| JP3906935B2 (ja) * | 1995-12-18 | 2007-04-18 | 杏林製薬株式会社 | Ｎ−置換ジオキソチアゾリジルベンズアミド誘導体及びその製造法 |
| DE69723680T9 (de) * | 1996-02-02 | 2004-11-04 | Merck & Co., Inc. | Antidiabetische mittel |
| ES2217392T3 (es) * | 1996-02-02 | 2004-11-01 | MERCK & CO., INC. | Agentes antidiabeticos. |
| ATE236137T1 (de) * | 1996-02-02 | 2003-04-15 | Merck & Co Inc | Heterocyclische verbindungen als antidiabetische mittel und für die behandlung von fettleibigkeit |
| US5801173A (en) * | 1996-05-06 | 1998-09-01 | Dr. Reddy's Research Foundation | Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
-
1998
- 1998-12-18 AU AU18334/99A patent/AU740733B2/en not_active Ceased
- 1998-12-18 EP EP98963283A patent/EP1040102B1/en not_active Expired - Lifetime
- 1998-12-18 CA CA002315397A patent/CA2315397C/en not_active Expired - Fee Related
- 1998-12-18 BR BR9813801-4A patent/BR9813801A/pt not_active Application Discontinuation
- 1998-12-18 AT AT98963283T patent/ATE352545T1/de not_active IP Right Cessation
- 1998-12-18 TR TR2000/01753T patent/TR200001753T2/xx unknown
- 1998-12-18 EA EA200000687A patent/EA200000687A1/ru unknown
- 1998-12-18 ES ES98963283T patent/ES2281146T3/es not_active Expired - Lifetime
- 1998-12-18 KR KR1020007006820A patent/KR20010033355A/ko not_active Withdrawn
- 1998-12-18 CN CN98812229A patent/CN1282325A/zh active Pending
- 1998-12-18 DE DE69836980T patent/DE69836980T2/de not_active Expired - Fee Related
- 1998-12-18 JP JP2000525402A patent/JP3373198B2/ja not_active Expired - Fee Related
- 1998-12-18 WO PCT/US1998/027139 patent/WO1999032465A1/en not_active Ceased
- 1998-12-18 ID IDW20001163A patent/ID24878A/id unknown
- 1998-12-18 PL PL98340958A patent/PL340958A1/xx not_active Application Discontinuation
- 1998-12-18 HU HU0101366A patent/HUP0101366A2/hu unknown
- 1998-12-18 SK SK921-2000A patent/SK9212000A3/sk unknown
- 1998-12-18 IL IL13613898A patent/IL136138A0/xx unknown
-
2000
- 2000-05-23 IS IS5506A patent/IS5506A/is unknown
- 2000-06-16 NO NO20003112A patent/NO20003112L/no not_active Application Discontinuation
- 2000-07-13 BG BG104602A patent/BG104602A/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TR200001753T2 (tr) | 2000-11-21 |
| BR9813801A (pt) | 2000-10-03 |
| WO1999032465A1 (en) | 1999-07-01 |
| CN1282325A (zh) | 2001-01-31 |
| KR20010033355A (ko) | 2001-04-25 |
| SK9212000A3 (en) | 2001-02-12 |
| ATE352545T1 (de) | 2007-02-15 |
| EP1040102A4 (en) | 2002-11-27 |
| NO20003112L (no) | 2000-08-18 |
| HUP0101366A2 (hu) | 2001-09-28 |
| AU740733B2 (en) | 2001-11-15 |
| CA2315397A1 (en) | 1999-07-01 |
| AU1833499A (en) | 1999-07-12 |
| EP1040102A1 (en) | 2000-10-04 |
| DE69836980D1 (de) | 2007-03-15 |
| IS5506A (is) | 2000-05-23 |
| NO20003112D0 (no) | 2000-06-16 |
| JP3373198B2 (ja) | 2003-02-04 |
| IL136138A0 (en) | 2001-05-20 |
| PL340958A1 (en) | 2001-03-12 |
| CA2315397C (en) | 2007-08-07 |
| BG104602A (bg) | 2001-01-31 |
| EA200000687A1 (ru) | 2000-12-25 |
| EP1040102B1 (en) | 2007-01-24 |
| JP2001526278A (ja) | 2001-12-18 |
| DE69836980T2 (de) | 2007-11-15 |
| ES2281146T3 (es) | 2007-09-16 |
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