ID24364A - Turunan-turunan pirolpirolon sebagai penghambat-penghambat pada neutropil elastase - Google Patents

Turunan-turunan pirolpirolon sebagai penghambat-penghambat pada neutropil elastase

Info

Publication number
ID24364A
ID24364A IDW20000665A ID20000665A ID24364A ID 24364 A ID24364 A ID 24364A ID W20000665 A IDW20000665 A ID W20000665A ID 20000665 A ID20000665 A ID 20000665A ID 24364 A ID24364 A ID 24364A
Authority
ID
Indonesia
Prior art keywords
pirolpirolon
obstacles
decreases
neutropil
elastase
Prior art date
Application number
IDW20000665A
Other languages
English (en)
Inventor
Michael D Dowle
Harry Finch
Lee A Harrison
Graham G A Inglis
Martin R Johnson
Simon J F Macdonald
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ID24364A publication Critical patent/ID24364A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
IDW20000665A 1997-09-09 1998-09-07 Turunan-turunan pirolpirolon sebagai penghambat-penghambat pada neutropil elastase ID24364A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9719187.8A GB9719187D0 (en) 1997-09-09 1997-09-09 Compounds

Publications (1)

Publication Number Publication Date
ID24364A true ID24364A (id) 2000-07-13

Family

ID=10818820

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20000665A ID24364A (id) 1997-09-09 1998-09-07 Turunan-turunan pirolpirolon sebagai penghambat-penghambat pada neutropil elastase

Country Status (24)

Country Link
US (1) US6228853B1 (id)
EP (1) EP1019406A1 (id)
JP (1) JP2001515902A (id)
KR (1) KR20010023830A (id)
CN (1) CN1278821A (id)
AP (1) AP2000001760A0 (id)
AU (1) AU9536098A (id)
BR (1) BR9811651A (id)
CA (1) CA2303249A1 (id)
EA (1) EA200000205A1 (id)
EE (1) EE200000137A (id)
GB (1) GB9719187D0 (id)
HR (1) HRP20000136A2 (id)
HU (1) HUP0003475A3 (id)
ID (1) ID24364A (id)
IL (1) IL134935A0 (id)
IS (1) IS5394A (id)
MA (1) MA26544A1 (id)
NO (1) NO20001200L (id)
PL (1) PL339186A1 (id)
SK (1) SK3242000A3 (id)
TR (1) TR200001026T2 (id)
WO (1) WO1999012931A1 (id)
ZA (1) ZA988162B (id)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2805818B1 (fr) * 2000-03-03 2002-04-26 Aventis Pharma Sa Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant
US7745226B2 (en) * 2005-04-06 2010-06-29 Quest Diagnostics Investments Incorporated Methods for detecting vitamin D metabolites
US7972868B2 (en) 2007-11-28 2011-07-05 Quest Diagnostics Investments Incorporated Methods for detecting dihydroxyvitamin D metabolites by mass spectrometry
US7977117B2 (en) 2009-12-03 2011-07-12 Quest Diagnostics Investments Incorprated Vitamin D metabolite determination utilizing mass spectrometry following derivatization
US20110240840A1 (en) 2009-12-11 2011-10-06 Quest Diagnostics Investments Incorporated Mass spectrometric determination of cookson-derivatized, non-metabolized vitamin d
EP3693734A3 (en) 2009-12-11 2020-12-23 Quest Diagnostics Investments Incorporated Mass spectrometry of steroidal compounds in multiplex samples
US20220354833A1 (en) 2019-09-17 2022-11-10 Mereo Biopharma 4 Limited Alvelestat for use in the treatment of graft rejection, bronchiolitis obliterans syndrome and graft versus host disease
WO2021209739A1 (en) 2020-04-16 2021-10-21 Mereo Biopharma 4 Limited Methods involving neutrophil elastase inhibitor alvelestat for treating respiratory disease mediated by alpha-1 antitrypsin deficiency
TW202325294A (zh) 2021-10-20 2023-07-01 英商梅瑞奧生物製藥4有限公司 用於治療纖維化之嗜中性球彈性蛋白酶抑制劑

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3983245A (en) 1975-02-06 1976-09-28 Smithkline Corporation Certain 4-(3-azacycloalkoxy or azacycloalkylmethoxy)benzoylbenzofurans or benzothiophenes
GB8512230D0 (en) * 1985-05-14 1985-06-19 Shell Internationale Researche Preparation of carboxylic acid salt
GB9211783D0 (en) 1992-06-04 1992-07-15 Ici Plc Amide derivatives
GB9402680D0 (en) * 1994-02-11 1994-04-06 Zeneca Ltd Pyrrolidine derivatives
CA2240467A1 (en) 1996-01-03 1997-07-17 Smithkline Beecham P.L.C. Carbamoyloxy derivatives of mutiline and their use as antibacterials
ATE261969T1 (de) * 1996-03-28 2004-04-15 Glaxo Group Ltd Pyrrolopyrrolone als inhibitoren von neutrophiler elastase

Also Published As

Publication number Publication date
GB9719187D0 (en) 1997-11-12
US6228853B1 (en) 2001-05-08
AU9536098A (en) 1999-03-29
SK3242000A3 (en) 2001-03-12
CA2303249A1 (en) 1999-03-18
EE200000137A (et) 2001-02-15
NO20001200L (no) 2000-05-08
ZA988162B (en) 2000-03-22
IL134935A0 (en) 2001-05-20
PL339186A1 (en) 2000-12-04
EA200000205A1 (ru) 2000-10-30
CN1278821A (zh) 2001-01-03
HRP20000136A2 (en) 2000-08-31
HUP0003475A2 (hu) 2001-09-28
IS5394A (is) 2000-03-03
AP2000001760A0 (en) 2000-03-31
TR200001026T2 (tr) 2000-09-21
WO1999012931A1 (en) 1999-03-18
MA26544A1 (fr) 2004-12-20
NO20001200D0 (no) 2000-03-08
JP2001515902A (ja) 2001-09-25
EP1019406A1 (en) 2000-07-19
KR20010023830A (ko) 2001-03-26
HUP0003475A3 (en) 2002-01-28
BR9811651A (pt) 2000-08-08

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