IS5394A - Pýrrólópýrrólón afleiður sem latar fyrir hlutleysiskirnings elastasa - Google Patents
Pýrrólópýrrólón afleiður sem latar fyrir hlutleysiskirnings elastasaInfo
- Publication number
- IS5394A IS5394A IS5394A IS5394A IS5394A IS 5394 A IS5394 A IS 5394A IS 5394 A IS5394 A IS 5394A IS 5394 A IS5394 A IS 5394A IS 5394 A IS5394 A IS 5394A
- Authority
- IS
- Iceland
- Prior art keywords
- elastase
- neutralization
- inhibit
- pyrrolopyrrolone
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9719187.8A GB9719187D0 (en) | 1997-09-09 | 1997-09-09 | Compounds |
| PCT/EP1998/005604 WO1999012931A1 (en) | 1997-09-09 | 1998-09-07 | Pyrrolopyrrolone derivatives as inhibitors of neutrophil elastase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS5394A true IS5394A (is) | 2000-03-03 |
Family
ID=10818820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS5394A IS5394A (is) | 1997-09-09 | 2000-03-03 | Pýrrólópýrrólón afleiður sem latar fyrir hlutleysiskirnings elastasa |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6228853B1 (is) |
| EP (1) | EP1019406A1 (is) |
| JP (1) | JP2001515902A (is) |
| KR (1) | KR20010023830A (is) |
| CN (1) | CN1278821A (is) |
| AP (1) | AP2000001760A0 (is) |
| AU (1) | AU9536098A (is) |
| BR (1) | BR9811651A (is) |
| CA (1) | CA2303249A1 (is) |
| EA (1) | EA200000205A1 (is) |
| EE (1) | EE200000137A (is) |
| GB (1) | GB9719187D0 (is) |
| HR (1) | HRP20000136A2 (is) |
| HU (1) | HUP0003475A3 (is) |
| ID (1) | ID24364A (is) |
| IL (1) | IL134935A0 (is) |
| IS (1) | IS5394A (is) |
| MA (1) | MA26544A1 (is) |
| NO (1) | NO20001200L (is) |
| PL (1) | PL339186A1 (is) |
| SK (1) | SK3242000A3 (is) |
| TR (1) | TR200001026T2 (is) |
| WO (1) | WO1999012931A1 (is) |
| ZA (1) | ZA988162B (is) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2805818B1 (fr) * | 2000-03-03 | 2002-04-26 | Aventis Pharma Sa | Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant |
| US7745226B2 (en) | 2005-04-06 | 2010-06-29 | Quest Diagnostics Investments Incorporated | Methods for detecting vitamin D metabolites |
| US7972868B2 (en) | 2007-11-28 | 2011-07-05 | Quest Diagnostics Investments Incorporated | Methods for detecting dihydroxyvitamin D metabolites by mass spectrometry |
| US7977117B2 (en) | 2009-12-03 | 2011-07-12 | Quest Diagnostics Investments Incorprated | Vitamin D metabolite determination utilizing mass spectrometry following derivatization |
| EP2510347B1 (en) | 2009-12-11 | 2019-03-20 | Quest Diagnostics Investments Incorporated | Mass spectrometry of steroidal compounds in multiplex samples |
| CN102753964A (zh) | 2009-12-11 | 2012-10-24 | 奎斯特诊断投资公司 | 非衍生的、非代谢的维生素d的质谱测定 |
| KR20220079527A (ko) | 2019-09-17 | 2022-06-13 | 메레오 바이오파마 4 리미티드 | 이식편 거부반응, 폐쇄성 세기관지염 증후군 및 이식편 대 숙주병의 치료에 사용하기 위한 알베레스타트 |
| IL297211A (en) | 2020-04-16 | 2022-12-01 | Mereo Biopharma 4 Ltd | Methods involving the neutrophil elastase inhibitor albalstat for the treatment of respiratory disease mediated by alpha-1 antitrypsin deficiency |
| AU2022373971A1 (en) | 2021-10-20 | 2024-04-04 | Mereo Biopharma 4 Limited | Neutrophil elastase inhibitors for use in the treatment of fibrosis |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3983245A (en) * | 1975-02-06 | 1976-09-28 | Smithkline Corporation | Certain 4-(3-azacycloalkoxy or azacycloalkylmethoxy)benzoylbenzofurans or benzothiophenes |
| GB8512230D0 (en) | 1985-05-14 | 1985-06-19 | Shell Internationale Researche | Preparation of carboxylic acid salt |
| GB9211783D0 (en) * | 1992-06-04 | 1992-07-15 | Ici Plc | Amide derivatives |
| GB9402680D0 (en) * | 1994-02-11 | 1994-04-06 | Zeneca Ltd | Pyrrolidine derivatives |
| JP4163254B2 (ja) * | 1996-01-03 | 2008-10-08 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | ムチリンのカルバモイルオキシ誘導体および抗細菌剤としてのそれらの使用 |
| AR006401A1 (es) * | 1996-03-28 | 1999-08-25 | Glaxo Group Ltd | Compuestos de pirrolopirrolona, una composicion farmaceutica que los contiene, su uso en la fabricacion de un medicamento y en terapia, procesospara su preparación y compuestos intermediarios para dichos procesos. |
-
1997
- 1997-09-09 GB GBGB9719187.8A patent/GB9719187D0/en not_active Ceased
-
1998
- 1998-09-07 SK SK324-2000A patent/SK3242000A3/sk unknown
- 1998-09-07 EA EA200000205A patent/EA200000205A1/ru unknown
- 1998-09-07 MA MA25244A patent/MA26544A1/fr unknown
- 1998-09-07 WO PCT/EP1998/005604 patent/WO1999012931A1/en not_active Application Discontinuation
- 1998-09-07 TR TR2000/01026T patent/TR200001026T2/xx unknown
- 1998-09-07 CN CN98810967A patent/CN1278821A/zh active Pending
- 1998-09-07 ZA ZA9808162A patent/ZA988162B/xx unknown
- 1998-09-07 BR BR9811651-7A patent/BR9811651A/pt not_active Application Discontinuation
- 1998-09-07 IL IL13493598A patent/IL134935A0/xx unknown
- 1998-09-07 EP EP98948905A patent/EP1019406A1/en not_active Withdrawn
- 1998-09-07 CA CA002303249A patent/CA2303249A1/en not_active Abandoned
- 1998-09-07 KR KR1020007002505A patent/KR20010023830A/ko not_active Application Discontinuation
- 1998-09-07 AU AU95360/98A patent/AU9536098A/en not_active Abandoned
- 1998-09-07 AP APAP/P/2000/001760A patent/AP2000001760A0/en unknown
- 1998-09-07 ID IDW20000665A patent/ID24364A/id unknown
- 1998-09-07 HU HU0003475A patent/HUP0003475A3/hu unknown
- 1998-09-07 EE EEP200000137A patent/EE200000137A/xx unknown
- 1998-09-07 PL PL98339186A patent/PL339186A1/xx not_active Application Discontinuation
- 1998-09-07 US US09/508,326 patent/US6228853B1/en not_active Expired - Fee Related
- 1998-09-07 JP JP2000510738A patent/JP2001515902A/ja active Pending
-
2000
- 2000-03-03 IS IS5394A patent/IS5394A/is unknown
- 2000-03-08 NO NO20001200A patent/NO20001200L/no not_active Application Discontinuation
- 2000-03-09 HR HR20000136A patent/HRP20000136A2/hr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2303249A1 (en) | 1999-03-18 |
| TR200001026T2 (tr) | 2000-09-21 |
| SK3242000A3 (en) | 2001-03-12 |
| ID24364A (id) | 2000-07-13 |
| HUP0003475A3 (en) | 2002-01-28 |
| HRP20000136A2 (en) | 2000-08-31 |
| GB9719187D0 (en) | 1997-11-12 |
| CN1278821A (zh) | 2001-01-03 |
| ZA988162B (en) | 2000-03-22 |
| PL339186A1 (en) | 2000-12-04 |
| MA26544A1 (fr) | 2004-12-20 |
| BR9811651A (pt) | 2000-08-08 |
| AP2000001760A0 (en) | 2000-03-31 |
| IL134935A0 (en) | 2001-05-20 |
| JP2001515902A (ja) | 2001-09-25 |
| KR20010023830A (ko) | 2001-03-26 |
| HUP0003475A2 (hu) | 2001-09-28 |
| NO20001200L (no) | 2000-05-08 |
| US6228853B1 (en) | 2001-05-08 |
| AU9536098A (en) | 1999-03-29 |
| EP1019406A1 (en) | 2000-07-19 |
| EA200000205A1 (ru) | 2000-10-30 |
| EE200000137A (et) | 2001-02-15 |
| NO20001200D0 (no) | 2000-03-08 |
| WO1999012931A1 (en) | 1999-03-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI980732A0 (fi) | Foerfarande foer koppling av dataoeverfoeringsstroemmar | |
| FI980343A0 (fi) | Foerfarande foer kontrollering av effekt | |
| FI980783A0 (fi) | Foerfarande foer utformning av en signaleringsfoerbindelse | |
| IS4837A (is) | Pýrrólópýrrólón afleiður sem latar fyrir hlutleysis elastasa | |
| FI980465A0 (fi) | Foerfarande foer installering av tjaenster | |
| IS5391A (is) | Pýrrólópýrrólón afleiður sem latar fyrir hlutleysiskirnings elastasa | |
| FI980327A0 (fi) | Foerfarande foer foermedling av telefonsamtal | |
| FI970156A0 (fi) | Foerfarande foer framstaellning av fiberplattor | |
| FI980150A0 (fi) | Foerfarande foer oeverfoering av bildinformation | |
| FI980735A0 (fi) | Foerfarande foer hantering av foerdroejning | |
| IS5394A (is) | Pýrrólópýrrólón afleiður sem latar fyrir hlutleysiskirnings elastasa | |
| FI104103B1 (fi) | Päällystyssauva | |
| FI963067A0 (fi) | Kuivausosalaite | |
| FI970477A0 (fi) | Foerfarande foer behandling av en oevantad nedkopplingsbegaeran | |
| FR2782671B3 (fr) | Livre | |
| FI980044A0 (fi) | Foerfarande foer behandling av en fiberbana | |
| FI971222A0 (fi) | Tillverkning av vaegmaerken | |
| FI980095A0 (fi) | Foerfarande foer byggande av fartyg | |
| EE03936B1 (et) | Laagrisõlm | |
| FI980710A0 (fi) | Foerfarande foer smaeltning av stenmaterial foer mineralullsproduktion | |
| FI980443A0 (fi) | Anordning foer maetning av en roerlig pappers- eller kartongbanas egenskaper | |
| FI980839A0 (fi) | Framstaellning av laktid | |
| DE29713908U1 (de) | Wandungsbauelement | |
| FI980146A0 (fi) | Foerfarande foer roentgenavbildning av huvud- och halsomraodet | |
| FI991149A (fi) | Kuumavesiboileri |