ID16081A - Penggunaan turunan trisiklik dari 1,4-dihidro-1,4-diokso-1h-naftalena senyawa-senyawa yang diperolehnya dan penerapannya dalam terapi - Google Patents

Penggunaan turunan trisiklik dari 1,4-dihidro-1,4-diokso-1h-naftalena senyawa-senyawa yang diperolehnya dan penerapannya dalam terapi

Info

Publication number
ID16081A
ID16081A IDP963710A ID963710A ID16081A ID 16081 A ID16081 A ID 16081A ID P963710 A IDP963710 A ID P963710A ID 963710 A ID963710 A ID 963710A ID 16081 A ID16081 A ID 16081A
Authority
ID
Indonesia
Prior art keywords
naftalena
triciclic
dioxos
demonstrations
complied
Prior art date
Application number
IDP963710A
Other languages
English (en)
Inventor
Boutherin Falson Odile
Desquand-Billiald Stephanie
Domagala-Le Marquer Florence
Favrou Anita
Finet Michel
Tembo Olivier
Torregrosa Jean Luc
Yannic Arnoult Sylvie
Original Assignee
Innothera Sa Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innothera Sa Lab filed Critical Innothera Sa Lab
Publication of ID16081A publication Critical patent/ID16081A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/24—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings
    • C07C225/26—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings
    • C07C225/30—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings of condensed quinone ring systems formed by two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/24—Quinones containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/32—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/60—Naphthoxazoles; Hydrogenated naphthoxazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/84—Naphthothiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/12—One of the condensed rings being a six-membered aromatic ring the other ring being at least seven-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IDP963710A 1995-12-12 1996-12-12 Penggunaan turunan trisiklik dari 1,4-dihidro-1,4-diokso-1h-naftalena senyawa-senyawa yang diperolehnya dan penerapannya dalam terapi ID16081A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9514683A FR2742153B1 (fr) 1995-12-12 1995-12-12 Utilisation de derives tricycliques du 1,4-dihydro-1,4- dioxo-1h-naphtalene, nouveaux composes obtenus et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ID16081A true ID16081A (id) 1997-09-04

Family

ID=9485393

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP963710A ID16081A (id) 1995-12-12 1996-12-12 Penggunaan turunan trisiklik dari 1,4-dihidro-1,4-diokso-1h-naftalena senyawa-senyawa yang diperolehnya dan penerapannya dalam terapi

Country Status (26)

Country Link
US (1) US6262095B1 (id)
EP (1) EP0876356B1 (id)
JP (1) JP2000501724A (id)
KR (1) KR19990072080A (id)
AP (1) AP889A (id)
AR (1) AR005054A1 (id)
AT (1) ATE207907T1 (id)
AU (1) AU716199B2 (id)
BR (1) BR9611935A (id)
CA (1) CA2240279A1 (id)
CZ (1) CZ181198A3 (id)
DE (1) DE69616598D1 (id)
EE (1) EE9800174A (id)
FR (1) FR2742153B1 (id)
HU (1) HUP9901247A3 (id)
ID (1) ID16081A (id)
IL (1) IL124558A0 (id)
LT (1) LT4491B (id)
LV (1) LV12188B (id)
NO (1) NO982696L (id)
NZ (1) NZ323967A (id)
OA (1) OA10696A (id)
PL (1) PL327168A1 (id)
RU (1) RU2178791C2 (id)
TR (1) TR199801069T2 (id)
WO (1) WO1997021684A1 (id)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003999A (en) * 1997-12-19 1999-07-12 Advanced Research And Technology Institute, Inc. Modulators of ryanodine receptors comprising 2-(aryl)-4,7-dioxobenzothiazoles and analogues thereof
WO2002050071A1 (en) * 2000-12-21 2002-06-27 Bristol-Myers Squibb Company Thiazolyl inhibitors of tec family tyrosine kinases
AR061478A1 (es) * 2006-06-19 2008-08-27 Takeda Pharmaceutical Compuesto triciclico y composicion farmaceutica
US7754463B2 (en) 2006-06-20 2010-07-13 Dana-Farber Cancer Institute Inhibitors of USP1 Deubiquitinating Enzyme Complex
CA2797719C (en) 2010-04-30 2019-11-26 Dana-Farber Cancer Institute, Inc. Small molecule inhibitors of usp1 deubiquitinating enzyme activity
US9040713B2 (en) * 2010-09-27 2015-05-26 Emory University Methods of managing blood sugar levels and compositions related thereto
US9725425B1 (en) 2014-02-25 2017-08-08 Dana-Farber Cancer Institute, Inc. Compounds and methods for treating cancer
RU2545091C1 (ru) * 2014-03-18 2015-03-27 Федеральное государственное бюджетное учреждение "Российский онкологический научный центр имени Н.Н. Блохина" Российской академии медицинских наук (ФГБУ "РОНЦ им. Н.Н. Блохина" РАМН) 1-R-4,9-ДИОКСО-1H-НАФТО[2,3-d][1,2,3]ТРИАЗОЛ-4-ОКСИМ-2-ОКСИДЫ И ИХ ПРОИЗВОДНЫЕ, ОБЛАДАЮЩИЕ ЦИТОТОКСИЧЕСКОЙ АКТИВНОСТЬЮ
US10829427B2 (en) 2015-12-18 2020-11-10 The Board Of Regents Of The University Of Texas System Naphthoquinones, pro-drugs, and methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3039925A (en) 1957-04-24 1962-06-19 Bayer Ag Compositions for the treatment of tuberculosis
US4746676A (en) 1984-09-12 1988-05-24 Rorer Pharmaceutical Corporation Carboxyalkyl dipeptide compounds
JPH05112533A (ja) * 1991-05-08 1993-05-07 Upjohn Co:The イミダゾベンゾキノン類およびこれを有効成分とする高血圧・鬱血性心不全の予防・治療剤

Also Published As

Publication number Publication date
WO1997021684A1 (fr) 1997-06-19
DE69616598D1 (de) 2001-12-06
LT98085A (en) 1998-11-25
IL124558A0 (en) 1998-12-06
JP2000501724A (ja) 2000-02-15
AR005054A1 (es) 1999-04-07
US6262095B1 (en) 2001-07-17
NZ323967A (en) 2000-06-23
HUP9901247A2 (hu) 1999-08-30
HUP9901247A3 (en) 2000-08-28
EP0876356A1 (fr) 1998-11-11
EE9800174A (et) 1998-12-15
LT4491B (lt) 1999-04-26
AP9801275A0 (en) 1998-06-30
OA10696A (fr) 2002-11-26
KR19990072080A (ko) 1999-09-27
PL327168A1 (en) 1998-11-23
BR9611935A (pt) 1999-05-18
NO982696D0 (no) 1998-06-11
ATE207907T1 (de) 2001-11-15
CA2240279A1 (fr) 1997-06-19
CZ181198A3 (cs) 1998-09-16
RU2178791C2 (ru) 2002-01-27
FR2742153A1 (fr) 1997-06-13
FR2742153B1 (fr) 1998-02-13
TR199801069T2 (xx) 1998-08-21
LV12188B (en) 1999-07-20
NO982696L (no) 1998-08-11
AU1101897A (en) 1997-07-03
EP0876356B1 (fr) 2001-10-31
AU716199B2 (en) 2000-02-24
LV12188A (lv) 1998-12-20
AP889A (en) 2000-11-17

Similar Documents

Publication Publication Date Title
ID17116A (id) Komposisi senyawa turunan 6-fenilpiridil-2-amina dan penggunaannya dalam pengobatan dan gangguan sistem syaraf pusat
RU98105966A (ru) Синтез и применение ретиноидных соединений, проявляющих отрицательную гормональную и/или антагонистическую активность
DE69628448D1 (de) Transdermale verabreichungsform von flurbiprofen
IL118247A0 (en) Use of R-enantiomer of N-propargyl-1-aminoindan and its salts
DE68927417T2 (de) Oligoribonukleotid-Derivate und ihre Anwendung als antivirale Mittel
ATE203161T1 (de) Polymer umhüllte tablette enthaltend amoxicillin und clavulanat
ID23673A (id) Formulasi farmasi yang terdiri dari amoksicilin dan klavulanat
ID16856A (id) Turunan-turunan indazol yang disubstitusi dan senyawa-senyawa yang berhubungan
DE69428927D1 (de) Maleinsäurecopolymer und dessen Anwendung
MA26553A1 (fr) Alpha-aryl-n-alkylnitrones et compositions pharmaceutiques contenant ceux-la
DE69305615D1 (de) Parfümiertes mittel
DE59507427D1 (de) Mischkristalle und feste Lösungen von 1,4-Diketopyrrolopyrrolen
ID18679A (id) Penggunaan terapi lanjutan
FI965204A0 (fi) Bromelaiinin lääkekäyttö
DE69620691D1 (de) Therapeutisches Mittel zur Behandlung der Hypercholesterinämie
ID17199A (id) Mikro-organisme pengurai hidrokarbon yang mengandung halogen dan pemakaiannya
ID16081A (id) Penggunaan turunan trisiklik dari 1,4-dihidro-1,4-diokso-1h-naftalena senyawa-senyawa yang diperolehnya dan penerapannya dalam terapi
DE59610836D1 (de) Mittel gegen parasitäre protozoen
DE69420178D1 (de) Flüssigkeitsauftragegerät und Herstellung desselben
DE69838785D1 (de) Pharmazeutische mittel zur behandlung von zerebralen amyloidosis
ID19147A (id) Ksilanase dan pemakaiannya
DE69417164T2 (de) Spender und dessen Verwendungsverfahren
DE4494231T1 (de) Therapeutische Zusammensetzung und ihre Anwendung
DE29512759U1 (de) Sitzanordnung von Belustigungsvorrichtungen
ID23156A (id) Turunan-turunan amidina, proses pembuatan komposisi dan penggunaannya