HUT75055A - Monohydrate of (e)-2'-deoxy-2'-(fluoromethylene)cytidine - Google Patents
Monohydrate of (e)-2'-deoxy-2'-(fluoromethylene)cytidineInfo
- Publication number
- HUT75055A HUT75055A HU9601848A HU9601848A HUT75055A HU T75055 A HUT75055 A HU T75055A HU 9601848 A HU9601848 A HU 9601848A HU 9601848 A HU9601848 A HU 9601848A HU T75055 A HUT75055 A HU T75055A
- Authority
- HU
- Hungary
- Prior art keywords
- fluoromethylene
- cytidine
- deoxy
- monohydrate
- neoplastic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17895294A | 1994-01-07 | 1994-01-07 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU9601848D0 HU9601848D0 (en) | 1996-09-30 |
| HUT75055A true HUT75055A (en) | 1997-03-28 |
| HU217849B HU217849B (hu) | 2000-04-28 |
Family
ID=22654587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9601848A HU217849B (hu) | 1994-01-07 | 1994-12-13 | (E)-2'-dezoxi-2'-(fluor-metilén)-citidin monohidrát |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0738273B1 (hu) |
| JP (1) | JPH09511227A (hu) |
| KR (1) | KR100330328B1 (hu) |
| CN (1) | CN1043231C (hu) |
| AT (1) | ATE186732T1 (hu) |
| AU (1) | AU684604B2 (hu) |
| CA (1) | CA2179987C (hu) |
| DE (1) | DE69421721T2 (hu) |
| DK (1) | DK0738273T3 (hu) |
| ES (1) | ES2141330T3 (hu) |
| FI (1) | FI114396B (hu) |
| GR (1) | GR3032614T3 (hu) |
| HU (1) | HU217849B (hu) |
| IL (1) | IL112242A (hu) |
| MX (1) | MX9500363A (hu) |
| NO (1) | NO306409B1 (hu) |
| NZ (1) | NZ279030A (hu) |
| TW (1) | TW397838B (hu) |
| WO (1) | WO1995018815A1 (hu) |
| ZA (1) | ZA9512B (hu) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2222614T3 (es) | 1997-11-12 | 2005-02-01 | Mitsubishi Chemical Corporation | Derivados de purina y medicina que los contiene como ingrediente activo. |
| DE60006663T2 (de) | 1999-05-11 | 2004-10-07 | Mitsubishi Chem Corp | Dihydrat eines purinderivates, medikamente die dieses als aktiven wirkstoff enthalten und zwischenprodukte zu dessen herstellung |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA898567B (en) * | 1988-11-15 | 1990-08-29 | Merrell Dow Pharma | Novel 2'-halomethylidene,2'-ethenylidene and 2'-ethynyl cytidine,uridine and guanosine derivatives |
| FI95269C (fi) * | 1989-05-15 | 1996-01-10 | Squibb Bristol Myers Co | 2',3'-dideoksi-inosiinimonohydraatin, 2',3'-dideoksi-2',3'-didehydrot ymidiinimonohydraatin ja 2',3'-dideoksi-2'-fluori-inosiinihemihydraatin antiviraalisia, hyvin vesiliukoisia, stabiileja, kiteisiä suoloja |
| JPH0615557B2 (ja) * | 1990-02-19 | 1994-03-02 | ヤマサ醤油株式会社 | ２’―デオキシ―２’―メチリデンシチジンの２水和物結晶 |
| NZ251886A (en) * | 1992-05-12 | 1996-02-27 | Merrell Dow Pharma | Ribonucleotide reductase inhibitors and their production |
-
1994
- 1994-12-13 NZ NZ279030A patent/NZ279030A/en unknown
- 1994-12-13 EP EP95907232A patent/EP0738273B1/en not_active Expired - Lifetime
- 1994-12-13 DE DE69421721T patent/DE69421721T2/de not_active Expired - Fee Related
- 1994-12-13 WO PCT/US1994/014648 patent/WO1995018815A1/en active IP Right Grant
- 1994-12-13 CN CN94194779A patent/CN1043231C/zh not_active Expired - Fee Related
- 1994-12-13 AT AT95907232T patent/ATE186732T1/de not_active IP Right Cessation
- 1994-12-13 ES ES95907232T patent/ES2141330T3/es not_active Expired - Lifetime
- 1994-12-13 AU AU15532/95A patent/AU684604B2/en not_active Ceased
- 1994-12-13 JP JP7518503A patent/JPH09511227A/ja active Pending
- 1994-12-13 CA CA002179987A patent/CA2179987C/en not_active Expired - Fee Related
- 1994-12-13 HU HU9601848A patent/HU217849B/hu not_active IP Right Cessation
- 1994-12-13 DK DK95907232T patent/DK0738273T3/da active
- 1994-12-13 KR KR1019960703658A patent/KR100330328B1/ko not_active IP Right Cessation
-
1995
- 1995-01-03 ZA ZA9512A patent/ZA9512B/xx unknown
- 1995-01-04 IL IL11224295A patent/IL112242A/xx not_active IP Right Cessation
- 1995-01-04 TW TW084100012A patent/TW397838B/zh not_active IP Right Cessation
- 1995-01-06 MX MX9500363A patent/MX9500363A/es unknown
-
1996
- 1996-07-05 NO NO962848A patent/NO306409B1/no unknown
- 1996-07-05 FI FI962769A patent/FI114396B/fi active IP Right Grant
-
2000
- 2000-02-09 GR GR20000400313T patent/GR3032614T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU1553295A (en) | 1995-08-01 |
| DK0738273T3 (da) | 2000-04-17 |
| NO962848L (no) | 1996-09-06 |
| MX9500363A (es) | 1998-04-30 |
| EP0738273B1 (en) | 1999-11-17 |
| ES2141330T3 (es) | 2000-03-16 |
| TW397838B (en) | 2000-07-11 |
| DE69421721D1 (de) | 1999-12-23 |
| HU217849B (hu) | 2000-04-28 |
| FI962769A0 (fi) | 1996-07-05 |
| FI962769A (fi) | 1996-07-05 |
| AU684604B2 (en) | 1997-12-18 |
| IL112242A (en) | 2000-08-31 |
| WO1995018815A1 (en) | 1995-07-13 |
| CA2179987C (en) | 1999-01-19 |
| CN1141045A (zh) | 1997-01-22 |
| NO962848D0 (no) | 1996-07-05 |
| HU9601848D0 (en) | 1996-09-30 |
| NZ279030A (en) | 1997-05-26 |
| JPH09511227A (ja) | 1997-11-11 |
| FI114396B (fi) | 2004-10-15 |
| IL112242A0 (en) | 1995-03-30 |
| ZA9512B (en) | 1995-09-11 |
| KR100330328B1 (ko) | 2002-12-05 |
| GR3032614T3 (en) | 2000-05-31 |
| ATE186732T1 (de) | 1999-12-15 |
| NO306409B1 (no) | 1999-11-01 |
| CN1043231C (zh) | 1999-05-05 |
| EP0738273A1 (en) | 1996-10-23 |
| CA2179987A1 (en) | 1995-07-13 |
| DE69421721T2 (de) | 2000-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of definitive patent protection due to non-payment of fees |