HUT74002A - Perfluoroalkyl-phenyl-substituted alkenyl-carboxylic-guanidine derivatives and pharmaceutical and diagnostical compositions containing them - Google Patents

Perfluoroalkyl-phenyl-substituted alkenyl-carboxylic-guanidine derivatives and pharmaceutical and diagnostical compositions containing them

Info

Publication number
HUT74002A
HUT74002A HU9501796A HU9501796A HUT74002A HU T74002 A HUT74002 A HU T74002A HU 9501796 A HU9501796 A HU 9501796A HU 9501796 A HU9501796 A HU 9501796A HU T74002 A HUT74002 A HU T74002A
Authority
HU
Hungary
Prior art keywords
perfluoroalkyl
phenyl
diagnostical
carboxylic
pharmaceutical
Prior art date
Application number
HU9501796A
Other languages
English (en)
Other versions
HU217971B (hu
HU9501796D0 (en
Inventor
Udo Albus
Heinz-Werner Kleemann
Hans-Jochen Lang
Wolfgang Scholz
Jan-Robert Schwark
Andreas Weichert
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of HU9501796D0 publication Critical patent/HU9501796D0/hu
Publication of HUT74002A publication Critical patent/HUT74002A/hu
Publication of HU217971B publication Critical patent/HU217971B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
HU9501796A 1994-06-20 1995-06-19 Perfluor-alkilcsoportot hordozó, fenilcsoporttal szubsztituált akrilsav-guanidin-származékok, alkalmazásuk és e vegyületeket tartalmazó gyógyászati készítmények HU217971B (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4421536A DE4421536A1 (de) 1994-06-20 1994-06-20 Perfluoralkylgruppen tragende phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (3)

Publication Number Publication Date
HU9501796D0 HU9501796D0 (en) 1995-08-28
HUT74002A true HUT74002A (en) 1996-10-28
HU217971B HU217971B (hu) 2000-05-28

Family

ID=6521042

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9501796A HU217971B (hu) 1994-06-20 1995-06-19 Perfluor-alkilcsoportot hordozó, fenilcsoporttal szubsztituált akrilsav-guanidin-származékok, alkalmazásuk és e vegyületeket tartalmazó gyógyászati készítmények

Country Status (22)

Country Link
US (1) US6025349A (hu)
EP (1) EP0688766B1 (hu)
JP (1) JP3718257B2 (hu)
KR (1) KR100368513B1 (hu)
CN (1) CN1062858C (hu)
AT (1) ATE178050T1 (hu)
AU (1) AU692539B2 (hu)
CA (1) CA2152137C (hu)
CZ (1) CZ287263B6 (hu)
DE (2) DE4421536A1 (hu)
DK (1) DK0688766T3 (hu)
ES (1) ES2130472T3 (hu)
FI (1) FI953003A (hu)
GR (1) GR3030231T3 (hu)
HU (1) HU217971B (hu)
IL (1) IL114216A (hu)
NO (1) NO304264B1 (hu)
NZ (1) NZ272373A (hu)
PL (1) PL179395B1 (hu)
SK (1) SK80395A3 (hu)
TW (1) TW332812B (hu)
ZA (1) ZA955027B (hu)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19518796A1 (de) 1995-05-22 1996-11-28 Hoechst Ag Fluorphenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19532553A1 (de) * 1995-09-04 1997-03-06 Hoechst Ag Verfahren zur Herstellung substituierter N-Ethyl-Glycinderivate
EP0765867A1 (de) * 1995-09-27 1997-04-02 Hoechst Aktiengesellschaft Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Antiarrhytmika oder Diagnostikum sowie sie enthaltendes Medikament
DE19546736A1 (de) * 1995-12-14 1997-06-19 Hoechst Ag Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate
CA2195697A1 (en) 1996-02-02 1997-08-03 Masahumi Kitano Novel substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof
DE19605610A1 (de) * 1996-02-15 1997-08-21 Hoechst Ag Substituierte Thiophenylalkenylcarbonsäureguanidide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
EP0886524A2 (en) * 1996-03-01 1998-12-30 Chiron Corporation Delivery of therapeutic agents to the prostate
EP0837055A1 (en) * 1996-07-30 1998-04-22 Hoechst Aktiengesellschaft Substituted Indanylidineacetylguanidines, process for their preparation, their use as medicaments or diagnostic and medicaments containing them
DE19633966A1 (de) * 1996-08-22 1998-02-26 Hoechst Ag Phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19737224A1 (de) 1997-08-27 1999-03-18 Hoechst Marion Roussel De Gmbh Pharmazeutisches Kombinationspräparat aus einem Inhibitor des Natrium-Wasserstoff-Austauschers und einem Arzneimittel zur Behandlung von Herz-Kreislauferkrankungen
US6958324B2 (en) 1998-12-02 2005-10-25 Inotek Pharmaceuticals Corporation Inosine compounds and their use for treating or preventing an inflamation or a reperfusion disease
WO2001052860A2 (en) * 2000-01-24 2001-07-26 Inotek Corporation Method and composition for modulating an immune response
DE10024319A1 (de) * 2000-05-17 2001-11-22 Merck Patent Gmbh Bisacylguanidine
DE10219545A1 (de) * 2002-04-26 2003-11-06 Lang Florian Regulation der Apoptose
WO2004112687A2 (en) 2003-06-26 2004-12-29 Biotron Limited Antiviral acylguanidine compounds and methods
AU2013205388B2 (en) * 2005-06-24 2016-05-05 Biotron Limited Antiviral compounds and methods
DK2826770T3 (en) 2005-06-24 2019-01-07 Biotron Ltd Acylguanidine compounds with antiviral activity
US7840502B2 (en) * 2007-06-13 2010-11-23 Microsoft Corporation Classification of images as advertisement images or non-advertisement images of web pages
DE102007039246A1 (de) * 2007-08-20 2009-02-26 Robert Bosch Gmbh Formmasse und Verfahren zur Herstellung einer Formmasse
AR085073A1 (es) * 2012-01-11 2013-09-11 Richmond Sa Com Ind Y Financiera Lab Compuestos con actividad antibacteriana, un procedimiento para su obtencion y composiciones farmaceuticas que los comprenden

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1298112A (en) * 1969-02-20 1972-11-29 Wander Ag Dr A Phenyl acetyl guanidine derivatives
US3780027A (en) * 1970-04-29 1973-12-18 Merck & Co Inc Anthranilic acid derivatives
US4101675A (en) * 1973-11-09 1978-07-18 Akzona Incorporated Novel 2,6-di-substituted phenyl-aminoquanidine containing compositions and methods of using same and pharmaceutical compositions containing the same and therapeutic method
GB1519762A (en) * 1974-08-09 1978-08-02 Wellcome Found Cinnamamides their preparation and pharmaceutical compositions containing them
DE2931735A1 (de) * 1979-08-04 1981-02-19 Beiersdorf Ag Neue substituierte phenylacetylguanidine und verfahren zu ihrer herstellung
US4544670A (en) * 1982-08-24 1985-10-01 William H. Rorer, Inc. Method of treating coccidiosis with acyl guanidines
EP0612723B1 (de) * 1993-02-20 1997-08-27 Hoechst Aktiengesellschaft Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, als Inhibitoren des zellulären Na+/H+-Austauschs oder als Diagnostikum sowie sie enthaltendes Medikament
JPH06256210A (ja) * 1993-03-10 1994-09-13 Hoechst Japan Ltd 骨関連転写制御因子様タンパク質およびその製造法
DE4318756A1 (de) * 1993-06-05 1994-12-08 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
CA2152137A1 (en) 1995-12-21
TW332812B (en) 1998-06-01
JPH0827093A (ja) 1996-01-30
KR100368513B1 (ko) 2003-03-19
CN1122329A (zh) 1996-05-15
EP0688766A1 (de) 1995-12-27
FI953003A0 (fi) 1995-06-16
HU217971B (hu) 2000-05-28
ZA955027B (en) 1996-02-08
JP3718257B2 (ja) 2005-11-24
EP0688766B1 (de) 1999-03-24
CN1062858C (zh) 2001-03-07
IL114216A0 (en) 1995-10-31
NO304264B1 (no) 1998-11-23
DE4421536A1 (de) 1995-12-21
SK80395A3 (en) 1996-06-05
GR3030231T3 (en) 1999-08-31
NO952450D0 (no) 1995-06-19
CA2152137C (en) 2007-11-13
DK0688766T3 (da) 1999-10-11
AU692539B2 (en) 1998-06-11
CZ160795A3 (en) 1996-05-15
CZ287263B6 (en) 2000-10-11
ES2130472T3 (es) 1999-07-01
AU2172095A (en) 1996-01-04
PL309168A1 (en) 1995-12-27
IL114216A (en) 2001-01-11
FI953003A (fi) 1995-12-21
ATE178050T1 (de) 1999-04-15
HU9501796D0 (en) 1995-08-28
DE59505412D1 (de) 1999-04-29
PL179395B1 (pl) 2000-08-31
NZ272373A (en) 1996-07-26
NO952450L (no) 1995-12-21
KR960000861A (ko) 1996-01-25
US6025349A (en) 2000-02-15

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee