HUT73172A - 3`-aziridino-anthracycline derivatives, pharmaceutical compns. contg. the said compds, process to prepare them and their use - Google Patents
3`-aziridino-anthracycline derivatives, pharmaceutical compns. contg. the said compds, process to prepare them and their useInfo
- Publication number
- HUT73172A HUT73172A HU9502662A HU9502662A HUT73172A HU T73172 A HUT73172 A HU T73172A HU 9502662 A HU9502662 A HU 9502662A HU 9502662 A HU9502662 A HU 9502662A HU T73172 A HUT73172 A HU T73172A
- Authority
- HU
- Hungary
- Prior art keywords
- group
- hydrogen
- linear
- alkyl
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939325417A GB9325417D0 (en) | 1993-12-13 | 1993-12-13 | 3'- aziridino-anthracycline derivatives |
PCT/EP1994/003840 WO1995016695A2 (en) | 1993-12-13 | 1994-11-21 | 3'-aziridino-anthracycline derivatives |
Publications (3)
Publication Number | Publication Date |
---|---|
HU9502662D0 HU9502662D0 (en) | 1995-11-28 |
HUT73172A true HUT73172A (en) | 1996-06-28 |
HU217630B HU217630B (hu) | 2000-03-28 |
Family
ID=10746494
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9502662A HU217630B (hu) | 1993-12-13 | 1994-11-21 | 3'-Aziridino-antraciklin-származékok, eljárás ezek előállítására és e vegyületeket tartalmazó gyógyászati készítmények |
Country Status (26)
Country | Link |
---|---|
US (1) | US5532218A (hu) |
EP (1) | EP0683788B1 (hu) |
JP (1) | JPH08506835A (hu) |
KR (1) | KR100352734B1 (hu) |
CN (1) | CN1039123C (hu) |
AT (1) | ATE157369T1 (hu) |
AU (1) | AU676625B2 (hu) |
CA (1) | CA2154890A1 (hu) |
DE (1) | DE69405214T2 (hu) |
DK (1) | DK0683788T3 (hu) |
ES (1) | ES2107294T3 (hu) |
FI (1) | FI108036B (hu) |
GB (1) | GB9325417D0 (hu) |
GR (1) | GR3025266T3 (hu) |
HK (1) | HK1011692A1 (hu) |
HU (1) | HU217630B (hu) |
IL (1) | IL111725A (hu) |
MY (1) | MY117086A (hu) |
NO (1) | NO304951B1 (hu) |
NZ (1) | NZ276401A (hu) |
PL (1) | PL178806B1 (hu) |
RU (1) | RU2149163C1 (hu) |
TW (1) | TW336235B (hu) |
UA (1) | UA43839C2 (hu) |
WO (1) | WO1995016695A2 (hu) |
ZA (1) | ZA949701B (hu) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5948896A (en) * | 1997-08-13 | 1999-09-07 | Gem Pharmaceuticals | Processes for preparing 13-deoxy anthracycline derivatives |
US5942605A (en) * | 1998-03-03 | 1999-08-24 | Gem Pharmaceuticals, Inc. | 5-imino-13-deoxy anthracycline derivatives, their uses, and processes for preparing them |
GB9806324D0 (en) * | 1998-03-24 | 1998-05-20 | Pharmacia & Upjohn Spa | Antitumour synergetic composition |
GB9808027D0 (en) * | 1998-04-15 | 1998-06-17 | Pharmacia & Upjohn Spa | 13-dihydro-3' aziridino anthracyclines |
GB9904387D0 (en) * | 1999-02-25 | 1999-04-21 | Pharmacia & Upjohn Spa | Antitumour synergistic composition |
GB9904386D0 (en) * | 1999-02-25 | 1999-04-21 | Pharmacia & Upjohn Spa | Antitumour synergistic composition |
GB0006601D0 (en) * | 2000-03-17 | 2000-05-10 | Pharmacia & Upjohn Spa | Crystalline alkycycline derivative |
GB0117403D0 (en) * | 2001-07-17 | 2001-09-05 | Pharmacia & Upjohn Spa | Solvent-free crystalline anthracycline derivatives |
WO2006124720A1 (en) * | 2005-05-12 | 2006-11-23 | The Ohio State University Research Foundation | Multidrug resistant anticancer anthracyclines |
CN101555264B (zh) * | 2008-04-11 | 2014-09-03 | 天津和美生物技术有限公司 | 具有高活性的四环蒽醌类抗生素的衍生物及其制备和应用 |
CN101912600B (zh) * | 2010-01-11 | 2014-01-29 | 杨国汉 | 改善胰岛素在溶液中稳定性的方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54141759A (en) * | 1978-04-24 | 1979-11-05 | Microbial Chem Res Found | Novel anthracycline derivative |
GB8614323D0 (en) * | 1986-06-12 | 1986-07-16 | Erba Farmitalia | Anthracyclines |
US5413992A (en) * | 1992-07-31 | 1995-05-09 | The Scripps Research Institute | Daunomycin derivative with reduced cytotoxicity toward normal cells |
-
1993
- 1993-12-13 GB GB939325417A patent/GB9325417D0/en active Pending
-
1994
- 1994-11-21 WO PCT/EP1994/003840 patent/WO1995016695A2/en active IP Right Grant
- 1994-11-21 RU RU95120191A patent/RU2149163C1/ru not_active IP Right Cessation
- 1994-11-21 JP JP7516486A patent/JPH08506835A/ja not_active Ceased
- 1994-11-21 DK DK95901401.0T patent/DK0683788T3/da active
- 1994-11-21 CN CN94191153A patent/CN1039123C/zh not_active Expired - Fee Related
- 1994-11-21 ES ES95901401T patent/ES2107294T3/es not_active Expired - Lifetime
- 1994-11-21 DE DE69405214T patent/DE69405214T2/de not_active Expired - Fee Related
- 1994-11-21 AU AU10660/95A patent/AU676625B2/en not_active Ceased
- 1994-11-21 EP EP95901401A patent/EP0683788B1/en not_active Expired - Lifetime
- 1994-11-21 US US08/345,450 patent/US5532218A/en not_active Expired - Fee Related
- 1994-11-21 KR KR1019950703348A patent/KR100352734B1/ko not_active IP Right Cessation
- 1994-11-21 AT AT95901401T patent/ATE157369T1/de not_active IP Right Cessation
- 1994-11-21 HU HU9502662A patent/HU217630B/hu not_active IP Right Cessation
- 1994-11-21 NZ NZ276401A patent/NZ276401A/en unknown
- 1994-11-21 PL PL94310177A patent/PL178806B1/pl not_active IP Right Cessation
- 1994-11-21 CA CA002154890A patent/CA2154890A1/en not_active Abandoned
- 1994-11-21 UA UA95083705A patent/UA43839C2/uk unknown
- 1994-11-22 IL IL11172594A patent/IL111725A/en not_active IP Right Cessation
- 1994-11-23 MY MYPI94003127A patent/MY117086A/en unknown
- 1994-11-30 TW TW083111129A patent/TW336235B/zh active
- 1994-12-06 ZA ZA949701A patent/ZA949701B/xx unknown
-
1995
- 1995-08-09 FI FI953784A patent/FI108036B/fi not_active IP Right Cessation
- 1995-08-11 NO NO953163A patent/NO304951B1/no not_active IP Right Cessation
-
1997
- 1997-11-05 GR GR970402904T patent/GR3025266T3/el unknown
-
1998
- 1998-12-03 HK HK98112738A patent/HK1011692A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of definitive patent protection due to non-payment of fees |