HUT64239A - Contrast materials for echo - Google Patents

Contrast materials for echo

Info

Publication number
HUT64239A
HUT64239A HU9301703A HU9301703A HUT64239A HU T64239 A HUT64239 A HU T64239A HU 9301703 A HU9301703 A HU 9301703A HU 9301703 A HU9301703 A HU 9301703A HU T64239 A HUT64239 A HU T64239A
Authority
HU
Hungary
Prior art keywords
echo
contrast materials
stabilisation
demonstration
absorption
Prior art date
Application number
HU9301703A
Other languages
English (en)
Other versions
HU9301703D0 (en
HU220763B1 (hu
Inventor
Klaus-Dieter Beller
Rudolf Linder
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6422745&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUT64239(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of HU9301703D0 publication Critical patent/HU9301703D0/hu
Publication of HUT64239A publication Critical patent/HUT64239A/hu
Publication of HU220763B1 publication Critical patent/HU220763B1/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Acoustics & Sound (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Graft Or Block Polymers (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Fish Paste Products (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Radiation-Therapy Devices (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
HU9301703A 1991-01-09 1992-01-04 Polioxietilén-polioxipropilén-polimereket és negatív töltésű foszfolipideket tartalmazó visszhang-kontrasztanyagok és eljárás előállításukra HU220763B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4100470A DE4100470A1 (de) 1991-01-09 1991-01-09 Echokontrastmittel
PCT/EP1992/000012 WO1992011873A1 (de) 1991-01-09 1992-01-04 Echokontrastmittel

Publications (3)

Publication Number Publication Date
HU9301703D0 HU9301703D0 (en) 1993-09-28
HUT64239A true HUT64239A (en) 1993-12-28
HU220763B1 HU220763B1 (hu) 2002-05-28

Family

ID=6422745

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9301703A HU220763B1 (hu) 1991-01-09 1992-01-04 Polioxietilén-polioxipropilén-polimereket és negatív töltésű foszfolipideket tartalmazó visszhang-kontrasztanyagok és eljárás előállításukra

Country Status (25)

Country Link
US (1) US5599523A (hu)
EP (2) EP0566601B2 (hu)
JP (1) JP3290655B2 (hu)
KR (1) KR100203221B1 (hu)
AT (1) ATE126708T1 (hu)
AU (1) AU652803B2 (hu)
BG (1) BG61667B2 (hu)
CA (1) CA2098915C (hu)
CZ (1) CZ280939B6 (hu)
DE (3) DE4100470A1 (hu)
DK (1) DK0566601T4 (hu)
ES (1) ES2079176T5 (hu)
FI (1) FI119913B (hu)
GR (1) GR3017925T3 (hu)
HK (1) HK1006147A1 (hu)
HU (1) HU220763B1 (hu)
IE (1) IE70131B1 (hu)
IL (1) IL100607A (hu)
NZ (1) NZ241246A (hu)
PL (1) PL167253B1 (hu)
RU (1) RU2091079C1 (hu)
SK (1) SK278776B6 (hu)
UA (1) UA27121C2 (hu)
WO (1) WO1992011873A1 (hu)
ZA (1) ZA92118B (hu)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
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US5922304A (en) * 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
US20020150539A1 (en) 1989-12-22 2002-10-17 Unger Evan C. Ultrasound imaging and treatment
US5578292A (en) 1991-11-20 1996-11-26 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US7083778B2 (en) * 1991-05-03 2006-08-01 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US20040208826A1 (en) * 1990-04-02 2004-10-21 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5445813A (en) * 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
IN172208B (hu) 1990-04-02 1993-05-01 Sint Sa
US6613306B1 (en) 1990-04-02 2003-09-02 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US6989141B2 (en) * 1990-05-18 2006-01-24 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US20010024638A1 (en) * 1992-11-02 2001-09-27 Michel Schneider Stable microbubble suspensions as enhancement agents for ultrasound echography and dry formulations thereof
USRE39146E1 (en) 1990-04-02 2006-06-27 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US20030194376A1 (en) * 1990-05-18 2003-10-16 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
GB9106686D0 (en) * 1991-03-28 1991-05-15 Hafslund Nycomed As Improvements in or relating to contrast agents
US5205290A (en) 1991-04-05 1993-04-27 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
GB9107628D0 (en) 1991-04-10 1991-05-29 Moonbrook Limited Preparation of diagnostic agents
US5993805A (en) 1991-04-10 1999-11-30 Quadrant Healthcare (Uk) Limited Spray-dried microparticles and their use as therapeutic vehicles
US5409688A (en) * 1991-09-17 1995-04-25 Sonus Pharmaceuticals, Inc. Gaseous ultrasound contrast media
US6875420B1 (en) 1991-09-17 2005-04-05 Amersham Health As Method of ultrasound imaging
MX9205298A (es) * 1991-09-17 1993-05-01 Steven Carl Quay Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido
EP0605477B2 (en) * 1991-09-17 2007-06-20 GE Healthcare AS Gaseous ultrasound contrast media
US6723303B1 (en) 1991-09-17 2004-04-20 Amersham Health, As Ultrasound contrast agents including protein stabilized microspheres of perfluoropropane, perfluorobutane or perfluoropentane
GB9200388D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
IL104084A (en) * 1992-01-24 1996-09-12 Bracco Int Bv Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them
US5464696A (en) * 1992-08-13 1995-11-07 Bracco International B.V. Particles for NMR imaging
GB9221329D0 (en) * 1992-10-10 1992-11-25 Delta Biotechnology Ltd Preparation of further diagnostic agents
IL108416A (en) 1993-01-25 1998-10-30 Sonus Pharma Inc Colloids with phase difference as contrast ultrasound agents
US5558855A (en) * 1993-01-25 1996-09-24 Sonus Pharmaceuticals Phase shift colloids as ultrasound contrast agents
JP3621413B2 (ja) * 1993-01-25 2005-02-16 アマシャム・ヘルス・エーエス 超音波造影剤としての相転移コロイド
US5716597A (en) * 1993-06-04 1998-02-10 Molecular Biosystems, Inc. Emulsions as contrast agents and method of use
CA2164813C (en) 1993-07-30 2009-11-24 Ernest G. Schutt Stabilized microbubble compositions for ultrasound
US5798091A (en) 1993-07-30 1998-08-25 Alliance Pharmaceutical Corp. Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
DE4328642A1 (de) * 1993-08-26 1995-03-02 Byk Gulden Lomberg Chem Fab Ultraschallkontrastmittel
GB9318288D0 (en) * 1993-09-03 1993-10-20 Nycomed Imaging As Improvements in or relating to contrast agents
US7083572B2 (en) 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
PL182223B1 (pl) * 1993-12-15 2001-11-30 Bracco Research Sa Biokompatybilna faza rozproszona do otrzymywania srodka kontrastowego do badan ultradzwiekowych, srodek kontrastowy do badan ultradzwiekowych, suchy preparat srodka kontrastowego oraz dwuskladnikowy zestaw do otrzymywania srodka kontrastowego do badan ultradzwiekowych PL PL PL
GB9417941D0 (en) * 1994-09-06 1994-10-26 Nycomed Imaging As Improvements in or relating to contrast agents
US5540909A (en) * 1994-09-28 1996-07-30 Alliance Pharmaceutical Corp. Harmonic ultrasound imaging with microbubbles
GB9423419D0 (en) 1994-11-19 1995-01-11 Andaris Ltd Preparation of hollow microcapsules
US5804162A (en) 1995-06-07 1998-09-08 Alliance Pharmaceutical Corp. Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
US6521211B1 (en) 1995-06-07 2003-02-18 Bristol-Myers Squibb Medical Imaging, Inc. Methods of imaging and treatment with targeted compositions
WO2004073750A1 (en) 1995-06-07 2004-09-02 Harald Dugstad Improvements in or relating to contrast agents
DE69721235T2 (de) 1996-02-19 2004-02-05 Amersham Health As Verbesserungen an (oder im bezug auf) kontrastmittel
DE69729088T2 (de) * 1996-03-05 2005-05-12 Acusphere, Inc., Cambridge Mikroverkapselte fluorierte gase zur anwendung als bilderzeugende mittel
ATE345682T1 (de) 1996-05-01 2006-12-15 Imarx Pharmaceutical Corp In vitro verfahren zum einbringen von nukleinsäuren in eine zelle
DE19626530A1 (de) * 1996-07-02 1998-01-15 Byk Gulden Lomberg Chem Fab MR-Kontrastmittelzubereitungen
ES2316157T3 (es) * 1996-08-02 2009-04-01 Ge Healthcare As Mejoras en o relativas a agentes de contraste.
US6017310A (en) * 1996-09-07 2000-01-25 Andaris Limited Use of hollow microcapsules
US5846517A (en) 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
US6068600A (en) * 1996-12-06 2000-05-30 Quadrant Healthcare (Uk) Limited Use of hollow microcapsules
GB9701237D0 (en) * 1997-01-22 1997-03-12 Nycomed Imaging As Improvements in or relating to contrast agents
US6054118A (en) * 1997-01-22 2000-04-25 Nycomed Imaging As Contrast agents comprising two types of gas-containing microparticles
US6537246B1 (en) 1997-06-18 2003-03-25 Imarx Therapeutics, Inc. Oxygen delivery agents and uses for the same
US7452551B1 (en) 2000-10-30 2008-11-18 Imarx Therapeutics, Inc. Targeted compositions for diagnostic and therapeutic use
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
DE19805012A1 (de) * 1998-02-07 1999-08-12 Thomas Gieselmann Kontrastmittel zur Verwendung als Diagnostikum bei bildgebenden Verfahren sowie seine Herstellung
GB9912356D0 (en) 1999-05-26 1999-07-28 Btg Int Ltd Generation of microfoam
US8512680B2 (en) 2001-08-08 2013-08-20 Btg International Ltd. Injectables in foam, new pharmaceutical applications
CN1960705B (zh) 2003-11-17 2010-11-24 英国技术集团国际有限公司 治疗性泡沫
US8048439B2 (en) 2003-11-17 2011-11-01 Btg International Ltd. Therapeutic foam
US8012457B2 (en) 2004-06-04 2011-09-06 Acusphere, Inc. Ultrasound contrast agent dosage formulation
GB0509824D0 (en) 2005-05-13 2005-06-22 Btg Int Ltd Therapeutic foam
WO2007070827A2 (en) * 2005-12-15 2007-06-21 Bristol-Myers Squibb Pharma Company Contrast agents for myocardium perfusion imaging

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3141641A1 (de) * 1981-10-16 1983-04-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen Ultraschall-kontrastmittel und dessen herstellung
US4900540A (en) * 1983-06-20 1990-02-13 Trustees Of The University Of Massachusetts Lipisomes containing gas for ultrasound detection
ATE65410T1 (de) * 1987-11-27 1991-08-15 Akzo Nv Stabilisierung von antikoerpern.
IN172208B (hu) * 1990-04-02 1993-05-01 Sint Sa

Also Published As

Publication number Publication date
HU9301703D0 (en) 1993-09-28
FI933137A0 (fi) 1993-07-08
IL100607A (en) 1996-07-23
FI119913B (fi) 2009-05-15
JP2000509363A (ja) 2000-07-25
IE70131B1 (en) 1996-10-30
BG61667B2 (bg) 1998-02-27
US5599523A (en) 1997-02-04
JP3290655B2 (ja) 2002-06-10
CZ178093A3 (en) 1994-04-13
DE4290068D2 (de) 1993-10-07
EP0566601A1 (de) 1993-10-27
HU220763B1 (hu) 2002-05-28
DK0566601T3 (da) 1995-12-18
DE4100470A1 (de) 1992-07-16
IL100607A0 (en) 1992-09-06
DE59203392D1 (de) 1995-09-28
FI933137L (fi) 1993-07-08
RU2091079C1 (ru) 1997-09-27
DK0566601T4 (da) 2007-05-29
GR3017925T3 (en) 1996-01-31
CZ280939B6 (cs) 1996-05-15
ATE126708T1 (de) 1995-09-15
EP0566601B1 (de) 1995-08-23
SK72993A3 (en) 1994-04-06
CA2098915A1 (en) 1992-07-10
IE920038A1 (en) 1992-07-15
WO1992011873A1 (de) 1992-07-23
PL167253B1 (pl) 1995-08-31
ES2079176T3 (es) 1996-01-01
ES2079176T5 (es) 2007-10-16
AU1154792A (en) 1992-08-17
UA27121C2 (uk) 2000-02-28
KR100203221B1 (ko) 1999-06-15
KR930703023A (ko) 1993-11-29
EP0494615A1 (de) 1992-07-15
EP0566601B2 (de) 2007-02-21
AU652803B2 (en) 1994-09-08
CA2098915C (en) 2005-05-17
NZ241246A (en) 1994-01-26
HK1006147A1 (en) 1999-02-12
ZA92118B (en) 1992-08-26
SK278776B6 (sk) 1998-02-04

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Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: ALTANA PHARMA AG, DE

Free format text: FORMER OWNER(S): BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH., DE