HUT64239A - Contrast materials for echo - Google Patents
Contrast materials for echoInfo
- Publication number
- HUT64239A HUT64239A HU9301703A HU9301703A HUT64239A HU T64239 A HUT64239 A HU T64239A HU 9301703 A HU9301703 A HU 9301703A HU 9301703 A HU9301703 A HU 9301703A HU T64239 A HUT64239 A HU T64239A
- Authority
- HU
- Hungary
- Prior art keywords
- echo
- contrast materials
- stabilisation
- demonstration
- absorption
- Prior art date
Links
- 239000002872 contrast media Substances 0.000 title 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000002961 echo contrast media Substances 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- -1 polyoxyethylene Polymers 0.000 abstract 1
- 229920001451 polypropylene glycol Polymers 0.000 abstract 1
- 230000006641 stabilisation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Acoustics & Sound (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Graft Or Block Polymers (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Fish Paste Products (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Radiation-Therapy Devices (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4100470A DE4100470A1 (de) | 1991-01-09 | 1991-01-09 | Echokontrastmittel |
| PCT/EP1992/000012 WO1992011873A1 (de) | 1991-01-09 | 1992-01-04 | Echokontrastmittel |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU9301703D0 HU9301703D0 (en) | 1993-09-28 |
| HUT64239A true HUT64239A (en) | 1993-12-28 |
| HU220763B1 HU220763B1 (hu) | 2002-05-28 |
Family
ID=6422745
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9301703A HU220763B1 (hu) | 1991-01-09 | 1992-01-04 | Polioxietilén-polioxipropilén-polimereket és negatív töltésű foszfolipideket tartalmazó visszhang-kontrasztanyagok és eljárás előállításukra |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5599523A (hu) |
| EP (2) | EP0566601B2 (hu) |
| JP (1) | JP3290655B2 (hu) |
| KR (1) | KR100203221B1 (hu) |
| AT (1) | ATE126708T1 (hu) |
| AU (1) | AU652803B2 (hu) |
| BG (1) | BG61667B2 (hu) |
| CA (1) | CA2098915C (hu) |
| CZ (1) | CZ280939B6 (hu) |
| DE (3) | DE4100470A1 (hu) |
| DK (1) | DK0566601T4 (hu) |
| ES (1) | ES2079176T5 (hu) |
| FI (1) | FI119913B (hu) |
| GR (1) | GR3017925T3 (hu) |
| HK (1) | HK1006147A1 (hu) |
| HU (1) | HU220763B1 (hu) |
| IE (1) | IE70131B1 (hu) |
| IL (1) | IL100607A (hu) |
| NZ (1) | NZ241246A (hu) |
| PL (1) | PL167253B1 (hu) |
| RU (1) | RU2091079C1 (hu) |
| SK (1) | SK278776B6 (hu) |
| UA (1) | UA27121C2 (hu) |
| WO (1) | WO1992011873A1 (hu) |
| ZA (1) | ZA92118B (hu) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5922304A (en) * | 1989-12-22 | 1999-07-13 | Imarx Pharmaceutical Corp. | Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents |
| US20020150539A1 (en) | 1989-12-22 | 2002-10-17 | Unger Evan C. | Ultrasound imaging and treatment |
| US5578292A (en) | 1991-11-20 | 1996-11-26 | Bracco International B.V. | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof |
| US7083778B2 (en) * | 1991-05-03 | 2006-08-01 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
| US20040208826A1 (en) * | 1990-04-02 | 2004-10-21 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
| US5445813A (en) * | 1992-11-02 | 1995-08-29 | Bracco International B.V. | Stable microbubble suspensions as enhancement agents for ultrasound echography |
| IN172208B (hu) | 1990-04-02 | 1993-05-01 | Sint Sa | |
| US6613306B1 (en) | 1990-04-02 | 2003-09-02 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
| US6989141B2 (en) * | 1990-05-18 | 2006-01-24 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
| US20010024638A1 (en) * | 1992-11-02 | 2001-09-27 | Michel Schneider | Stable microbubble suspensions as enhancement agents for ultrasound echography and dry formulations thereof |
| USRE39146E1 (en) | 1990-04-02 | 2006-06-27 | Bracco International B.V. | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof |
| US20030194376A1 (en) * | 1990-05-18 | 2003-10-16 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
| AU636481B2 (en) * | 1990-05-18 | 1993-04-29 | Bracco International B.V. | Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography |
| GB9106686D0 (en) * | 1991-03-28 | 1991-05-15 | Hafslund Nycomed As | Improvements in or relating to contrast agents |
| US5205290A (en) | 1991-04-05 | 1993-04-27 | Unger Evan C | Low density microspheres and their use as contrast agents for computed tomography |
| GB9107628D0 (en) | 1991-04-10 | 1991-05-29 | Moonbrook Limited | Preparation of diagnostic agents |
| US5993805A (en) | 1991-04-10 | 1999-11-30 | Quadrant Healthcare (Uk) Limited | Spray-dried microparticles and their use as therapeutic vehicles |
| US5409688A (en) * | 1991-09-17 | 1995-04-25 | Sonus Pharmaceuticals, Inc. | Gaseous ultrasound contrast media |
| US6875420B1 (en) | 1991-09-17 | 2005-04-05 | Amersham Health As | Method of ultrasound imaging |
| MX9205298A (es) * | 1991-09-17 | 1993-05-01 | Steven Carl Quay | Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido |
| EP0605477B2 (en) * | 1991-09-17 | 2007-06-20 | GE Healthcare AS | Gaseous ultrasound contrast media |
| US6723303B1 (en) | 1991-09-17 | 2004-04-20 | Amersham Health, As | Ultrasound contrast agents including protein stabilized microspheres of perfluoropropane, perfluorobutane or perfluoropentane |
| GB9200388D0 (en) * | 1992-01-09 | 1992-02-26 | Nycomed As | Improvements in or relating to contrast agents |
| IL104084A (en) * | 1992-01-24 | 1996-09-12 | Bracco Int Bv | Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them |
| US5464696A (en) * | 1992-08-13 | 1995-11-07 | Bracco International B.V. | Particles for NMR imaging |
| GB9221329D0 (en) * | 1992-10-10 | 1992-11-25 | Delta Biotechnology Ltd | Preparation of further diagnostic agents |
| IL108416A (en) | 1993-01-25 | 1998-10-30 | Sonus Pharma Inc | Colloids with phase difference as contrast ultrasound agents |
| US5558855A (en) * | 1993-01-25 | 1996-09-24 | Sonus Pharmaceuticals | Phase shift colloids as ultrasound contrast agents |
| JP3621413B2 (ja) * | 1993-01-25 | 2005-02-16 | アマシャム・ヘルス・エーエス | 超音波造影剤としての相転移コロイド |
| US5716597A (en) * | 1993-06-04 | 1998-02-10 | Molecular Biosystems, Inc. | Emulsions as contrast agents and method of use |
| CA2164813C (en) | 1993-07-30 | 2009-11-24 | Ernest G. Schutt | Stabilized microbubble compositions for ultrasound |
| US5798091A (en) | 1993-07-30 | 1998-08-25 | Alliance Pharmaceutical Corp. | Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement |
| DE4328642A1 (de) * | 1993-08-26 | 1995-03-02 | Byk Gulden Lomberg Chem Fab | Ultraschallkontrastmittel |
| GB9318288D0 (en) * | 1993-09-03 | 1993-10-20 | Nycomed Imaging As | Improvements in or relating to contrast agents |
| US7083572B2 (en) | 1993-11-30 | 2006-08-01 | Bristol-Myers Squibb Medical Imaging, Inc. | Therapeutic delivery systems |
| PL182223B1 (pl) * | 1993-12-15 | 2001-11-30 | Bracco Research Sa | Biokompatybilna faza rozproszona do otrzymywania srodka kontrastowego do badan ultradzwiekowych, srodek kontrastowy do badan ultradzwiekowych, suchy preparat srodka kontrastowego oraz dwuskladnikowy zestaw do otrzymywania srodka kontrastowego do badan ultradzwiekowych PL PL PL |
| GB9417941D0 (en) * | 1994-09-06 | 1994-10-26 | Nycomed Imaging As | Improvements in or relating to contrast agents |
| US5540909A (en) * | 1994-09-28 | 1996-07-30 | Alliance Pharmaceutical Corp. | Harmonic ultrasound imaging with microbubbles |
| GB9423419D0 (en) | 1994-11-19 | 1995-01-11 | Andaris Ltd | Preparation of hollow microcapsules |
| US5804162A (en) | 1995-06-07 | 1998-09-08 | Alliance Pharmaceutical Corp. | Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients |
| US6521211B1 (en) | 1995-06-07 | 2003-02-18 | Bristol-Myers Squibb Medical Imaging, Inc. | Methods of imaging and treatment with targeted compositions |
| WO2004073750A1 (en) | 1995-06-07 | 2004-09-02 | Harald Dugstad | Improvements in or relating to contrast agents |
| DE69721235T2 (de) | 1996-02-19 | 2004-02-05 | Amersham Health As | Verbesserungen an (oder im bezug auf) kontrastmittel |
| DE69729088T2 (de) * | 1996-03-05 | 2005-05-12 | Acusphere, Inc., Cambridge | Mikroverkapselte fluorierte gase zur anwendung als bilderzeugende mittel |
| ATE345682T1 (de) | 1996-05-01 | 2006-12-15 | Imarx Pharmaceutical Corp | In vitro verfahren zum einbringen von nukleinsäuren in eine zelle |
| DE19626530A1 (de) * | 1996-07-02 | 1998-01-15 | Byk Gulden Lomberg Chem Fab | MR-Kontrastmittelzubereitungen |
| ES2316157T3 (es) * | 1996-08-02 | 2009-04-01 | Ge Healthcare As | Mejoras en o relativas a agentes de contraste. |
| US6017310A (en) * | 1996-09-07 | 2000-01-25 | Andaris Limited | Use of hollow microcapsules |
| US5846517A (en) | 1996-09-11 | 1998-12-08 | Imarx Pharmaceutical Corp. | Methods for diagnostic imaging using a renal contrast agent and a vasodilator |
| US6068600A (en) * | 1996-12-06 | 2000-05-30 | Quadrant Healthcare (Uk) Limited | Use of hollow microcapsules |
| GB9701237D0 (en) * | 1997-01-22 | 1997-03-12 | Nycomed Imaging As | Improvements in or relating to contrast agents |
| US6054118A (en) * | 1997-01-22 | 2000-04-25 | Nycomed Imaging As | Contrast agents comprising two types of gas-containing microparticles |
| US6537246B1 (en) | 1997-06-18 | 2003-03-25 | Imarx Therapeutics, Inc. | Oxygen delivery agents and uses for the same |
| US7452551B1 (en) | 2000-10-30 | 2008-11-18 | Imarx Therapeutics, Inc. | Targeted compositions for diagnostic and therapeutic use |
| US20010003580A1 (en) | 1998-01-14 | 2001-06-14 | Poh K. Hui | Preparation of a lipid blend and a phospholipid suspension containing the lipid blend |
| DE19805012A1 (de) * | 1998-02-07 | 1999-08-12 | Thomas Gieselmann | Kontrastmittel zur Verwendung als Diagnostikum bei bildgebenden Verfahren sowie seine Herstellung |
| GB9912356D0 (en) | 1999-05-26 | 1999-07-28 | Btg Int Ltd | Generation of microfoam |
| US8512680B2 (en) | 2001-08-08 | 2013-08-20 | Btg International Ltd. | Injectables in foam, new pharmaceutical applications |
| CN1960705B (zh) | 2003-11-17 | 2010-11-24 | 英国技术集团国际有限公司 | 治疗性泡沫 |
| US8048439B2 (en) | 2003-11-17 | 2011-11-01 | Btg International Ltd. | Therapeutic foam |
| US8012457B2 (en) | 2004-06-04 | 2011-09-06 | Acusphere, Inc. | Ultrasound contrast agent dosage formulation |
| GB0509824D0 (en) | 2005-05-13 | 2005-06-22 | Btg Int Ltd | Therapeutic foam |
| WO2007070827A2 (en) * | 2005-12-15 | 2007-06-21 | Bristol-Myers Squibb Pharma Company | Contrast agents for myocardium perfusion imaging |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3141641A1 (de) * | 1981-10-16 | 1983-04-28 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Ultraschall-kontrastmittel und dessen herstellung |
| US4900540A (en) * | 1983-06-20 | 1990-02-13 | Trustees Of The University Of Massachusetts | Lipisomes containing gas for ultrasound detection |
| ATE65410T1 (de) * | 1987-11-27 | 1991-08-15 | Akzo Nv | Stabilisierung von antikoerpern. |
| IN172208B (hu) * | 1990-04-02 | 1993-05-01 | Sint Sa |
-
1991
- 1991-01-09 DE DE4100470A patent/DE4100470A1/de not_active Ceased
-
1992
- 1992-01-04 AT AT92901804T patent/ATE126708T1/de not_active IP Right Cessation
- 1992-01-04 RU RU9293052889A patent/RU2091079C1/ru active
- 1992-01-04 DE DE59203392T patent/DE59203392D1/de not_active Expired - Lifetime
- 1992-01-04 HK HK98105041A patent/HK1006147A1/xx not_active IP Right Cessation
- 1992-01-04 PL PL92299987A patent/PL167253B1/pl unknown
- 1992-01-04 CA CA002098915A patent/CA2098915C/en not_active Expired - Lifetime
- 1992-01-04 KR KR1019930702025A patent/KR100203221B1/ko not_active Expired - Lifetime
- 1992-01-04 DK DK92901804T patent/DK0566601T4/da active
- 1992-01-04 CZ CS931780A patent/CZ280939B6/cs not_active IP Right Cessation
- 1992-01-04 WO PCT/EP1992/000012 patent/WO1992011873A1/de not_active Ceased
- 1992-01-04 EP EP92901804A patent/EP0566601B2/de not_active Expired - Lifetime
- 1992-01-04 JP JP50166892A patent/JP3290655B2/ja not_active Expired - Lifetime
- 1992-01-04 DE DEEP9200012T patent/DE4290068D2/de not_active Expired - Lifetime
- 1992-01-04 EP EP92100093A patent/EP0494615A1/de active Pending
- 1992-01-04 SK SK729-93A patent/SK278776B6/sk unknown
- 1992-01-04 AU AU11547/92A patent/AU652803B2/en not_active Expired
- 1992-01-04 UA UA94040995A patent/UA27121C2/uk unknown
- 1992-01-04 HU HU9301703A patent/HU220763B1/hu unknown
- 1992-01-04 ES ES92901804T patent/ES2079176T5/es not_active Expired - Lifetime
- 1992-01-07 IE IE920038A patent/IE70131B1/en not_active IP Right Cessation
- 1992-01-07 IL IL10060792A patent/IL100607A/en not_active IP Right Cessation
- 1992-01-08 NZ NZ241246A patent/NZ241246A/en not_active IP Right Cessation
- 1992-01-08 ZA ZA92118A patent/ZA92118B/xx unknown
-
1993
- 1993-07-08 FI FI933137A patent/FI119913B/fi active IP Right Grant
-
1994
- 1994-02-28 BG BG098599A patent/BG61667B2/bg unknown
- 1994-11-22 US US08/347,206 patent/US5599523A/en not_active Expired - Lifetime
-
1995
- 1995-10-31 GR GR950403031T patent/GR3017925T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB9A | Succession in title |
Owner name: ALTANA PHARMA AG, DE Free format text: FORMER OWNER(S): BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH., DE |