HUT63830A - Process for producing sulfonamide derivatives and anticarcinogens comprising same - Google Patents
Process for producing sulfonamide derivatives and anticarcinogens comprising same Download PDFInfo
- Publication number
- HUT63830A HUT63830A HU9300688A HU9300688A HUT63830A HU T63830 A HUT63830 A HU T63830A HU 9300688 A HU9300688 A HU 9300688A HU 9300688 A HU9300688 A HU 9300688A HU T63830 A HUT63830 A HU T63830A
- Authority
- HU
- Hungary
- Prior art keywords
- amino
- sulfonamide
- carbonyl
- formula
- halogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/850,531 US5169860A (en) | 1992-03-13 | 1992-03-13 | Antitumor compositions and methods of treatment |
Publications (2)
Publication Number | Publication Date |
---|---|
HU9300688D0 HU9300688D0 (en) | 1993-05-28 |
HUT63830A true HUT63830A (en) | 1993-10-28 |
Family
ID=25308394
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9300688A HUT63830A (en) | 1992-03-13 | 1993-03-10 | Process for producing sulfonamide derivatives and anticarcinogens comprising same |
Country Status (19)
Country | Link |
---|---|
US (1) | US5169860A (ja) |
EP (1) | EP0560554A2 (ja) |
JP (1) | JPH0649052A (ja) |
KR (1) | KR930019655A (ja) |
CN (1) | CN1076447A (ja) |
AU (2) | AU662605B2 (ja) |
BR (1) | BR9301137A (ja) |
CA (1) | CA2091207A1 (ja) |
CZ (1) | CZ36893A3 (ja) |
FI (1) | FI931085A (ja) |
HU (1) | HUT63830A (ja) |
IL (1) | IL104981A0 (ja) |
MX (1) | MX9301296A (ja) |
MY (1) | MY111178A (ja) |
NO (1) | NO930891L (ja) |
NZ (1) | NZ247083A (ja) |
TW (1) | TW215083B (ja) |
YU (1) | YU16893A (ja) |
ZA (1) | ZA931645B (ja) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5254582A (en) * | 1992-02-05 | 1993-10-19 | Eli Lilly And Company | Antitumor compositions and methods |
CA2110524A1 (en) * | 1992-12-10 | 1994-06-11 | Gerald Burr Grindey | Antitumor compositions and methods of treatment |
US5270329A (en) * | 1992-12-10 | 1993-12-14 | Eli Lilly And Company | Antitumor compositions and methods of treatment |
ZA941500B (en) * | 1993-03-10 | 1995-09-04 | Lilly Co Eli | Antitumor compositions and methods of treatment |
US5529999A (en) * | 1994-03-04 | 1996-06-25 | Eli Lilly And Company | Antitumor compositions and methods of treatment |
CO4410190A1 (es) | 1994-09-19 | 1997-01-09 | Lilly Co Eli | 3-[4-(2-AMINOETOXI)-BENZOIL]-2-ARIL-6-HIDROXIBENZO [b] TIOFENO CRISTALINO |
US5629425A (en) * | 1994-09-19 | 1997-05-13 | Eli Lilly And Company | Haloalkyl hemisolvates of 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-piperidinoethoxy)-benzoyl]benzo[b]thiophene |
US5863936A (en) * | 1995-04-18 | 1999-01-26 | Geron Corporation | Telomerase inhibitors |
WO1997034888A1 (en) * | 1996-03-19 | 1997-09-25 | Eli Lilly And Company | SYNTHESIS OF 3-[4-(2-AMINOETHOXY)-BENZOYL]-2-ARYL-6-HYDROXY-BENZO[b]THIOPHENES |
EP1021437B1 (en) * | 1996-08-22 | 2001-11-14 | Dong Wha Pharmaceutical Industrial Co. Ltd. | Arylsulfonylimidazolone derivatives as an antitumor agent |
EP0929540A4 (en) * | 1996-10-04 | 2001-12-12 | Lilly Co Eli | ANTI-TUMOR COMPOSITIONS AND THERAPEUTIC METHODS |
ES2156550B1 (es) * | 1999-04-19 | 2002-02-01 | Univ Navarra Publica | Derivados de benzo(b) tiofenosulfonamida-1,1-dioxido y su uso como agentes antineoplasicos. |
JP4505876B2 (ja) * | 1999-05-25 | 2010-07-21 | 東ソー株式会社 | 4−ハロベンゾフラン誘導体及びその製造方法 |
TWI281916B (en) * | 2001-10-25 | 2007-06-01 | Lilly Co Eli | Antitumor compounds and methods |
US20050119318A1 (en) * | 2003-10-31 | 2005-06-02 | Hudyma Thomas W. | Inhibitors of HCV replication |
EP2224923A4 (en) | 2007-11-28 | 2013-05-15 | Sequoia Pharmaceuticals Inc | COMPOSITIONS AND METHOD FOR INHIBITING ZYTOCHROM P450 2D6 |
KR101300702B1 (ko) * | 2011-01-20 | 2013-08-26 | 대우조선해양 주식회사 | 탈가스 장치 |
CN103450149B (zh) * | 2012-06-01 | 2015-10-14 | 中国科学院上海有机化学研究所 | 苯基噻吩磺酰胺类化合物及其制备方法和用途 |
CN104564805B (zh) * | 2013-10-29 | 2017-11-10 | 海尔集团公司 | 一种离心风机的扇叶结构、离心风机及嵌入式空调内机 |
MA47440B1 (fr) | 2015-02-16 | 2021-08-31 | The Provost Fellows Found Scholars And The Other Members Of Board Of The College Of The Holy & Undiv | Sulfonylurées, composés apparentés, et leur utilisation |
WO2017184623A1 (en) | 2016-04-18 | 2017-10-26 | Ifm Therapeutics, Inc | Compounds and compositions for treating conditions associated with nlrp activity |
JP7235742B2 (ja) | 2017-07-07 | 2023-03-08 | インフレイゾーム リミテッド | 新規なスルホンアミドカルボキサミド化合物 |
CN117143042A (zh) | 2017-07-24 | 2023-12-01 | 诺华股份有限公司 | 用于治疗与nlrp活性相关的病症的化合物和组合物 |
WO2019034693A1 (en) | 2017-08-15 | 2019-02-21 | Inflazome Limited | SULFONYLURATES AND SULFONYLTHIOURES AS INHIBITORS OF NLRP3 |
CA3071150A1 (en) | 2017-08-15 | 2019-02-21 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors |
EP3668842A1 (en) | 2017-08-15 | 2020-06-24 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors |
WO2019092170A1 (en) | 2017-11-09 | 2019-05-16 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
EP3759077A1 (en) | 2018-03-02 | 2021-01-06 | Inflazome Limited | Novel compounds |
US20230011652A1 (en) * | 2018-10-24 | 2023-01-12 | Novartis Ag | Compounds and compositions for treating conditions associated with nlrp activity |
CN109384764B (zh) * | 2018-12-12 | 2021-09-03 | 中国科学院上海有机化学研究所 | 苯基噻吩磺酰胺类化合物、药物组合物、其制备方法和应用 |
WO2022022646A1 (zh) * | 2020-07-29 | 2022-02-03 | 南京明德新药研发有限公司 | 含硒五元杂芳环化合物 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3083207A (en) * | 1963-03-26 | Indolinesulfonylureas | ||
DE1144259B (de) * | 1956-05-29 | 1963-02-28 | Hoechst Ag | Verfahren zur Herstellung von Sulfonylharnstoffen |
US3097242A (en) * | 1960-06-29 | 1963-07-09 | Olin Mathieson | Hydrindene sulfonylureas |
DE1240866B (de) * | 1961-06-29 | 1967-05-24 | Heyden Chem Fab | Verfahren zur Herstellung von Indolin-6-sulfonylharnstoffen |
US3102121A (en) * | 1961-06-29 | 1963-08-27 | Olin Mathieson | Novel cumaransulfonylureas and 2,3-dihydrothionaphthenesulfonylureas |
NL295122A (ja) * | 1962-04-11 | |||
US3849110A (en) * | 1963-01-07 | 1974-11-19 | Lilly Co Eli | Herbicidal method employing aryl-sulfonylureas or salts thereof |
US3736122A (en) * | 1969-04-10 | 1973-05-29 | C Tung | Method of controlling plant growth |
AU1862083A (en) * | 1982-09-02 | 1984-03-08 | Duphar International Research B.V. | Tumor growth inhibitors |
CA1208561A (en) * | 1984-01-19 | 1986-07-29 | Marius S. Brouwer | Pharmaceutical compositions containing benzoylurea compounds |
US4845128A (en) * | 1984-06-27 | 1989-07-04 | Eli Lilly And Company | N([(4-trifluoromethylphenyl)amino]carbonyl)benzene sulfonamides |
GR862353B (en) * | 1985-09-23 | 1987-01-19 | Lilly Co Eli | Anti-tumor method and compounds |
CA1331464C (en) * | 1987-05-12 | 1994-08-16 | Eli Lilly And Company | Anti-tumor method and compounds |
ZA915371B (en) * | 1990-07-17 | 1993-03-31 | Lilly Co Eli | Antitumor compositions and methods of treatment |
-
1992
- 1992-03-13 US US07/850,531 patent/US5169860A/en not_active Expired - Fee Related
- 1992-04-08 TW TW081102695A patent/TW215083B/zh active
-
1993
- 1993-03-08 CZ CZ93368A patent/CZ36893A3/cs unknown
- 1993-03-08 CA CA002091207A patent/CA2091207A1/en not_active Abandoned
- 1993-03-08 IL IL104981A patent/IL104981A0/xx unknown
- 1993-03-08 ZA ZA931645A patent/ZA931645B/xx unknown
- 1993-03-08 EP EP93301732A patent/EP0560554A2/en not_active Withdrawn
- 1993-03-08 NZ NZ247083A patent/NZ247083A/en unknown
- 1993-03-09 MX MX9301296A patent/MX9301296A/es unknown
- 1993-03-10 HU HU9300688A patent/HUT63830A/hu unknown
- 1993-03-11 BR BR9301137A patent/BR9301137A/pt not_active Application Discontinuation
- 1993-03-11 NO NO93930891A patent/NO930891L/no unknown
- 1993-03-11 MY MYPI93000440A patent/MY111178A/en unknown
- 1993-03-11 KR KR1019930003657A patent/KR930019655A/ko not_active Application Discontinuation
- 1993-03-11 AU AU35198/93A patent/AU662605B2/en not_active Ceased
- 1993-03-11 FI FI931085A patent/FI931085A/fi not_active Application Discontinuation
- 1993-03-11 YU YU16893A patent/YU16893A/sh unknown
- 1993-03-12 CN CN93101988A patent/CN1076447A/zh active Pending
- 1993-03-12 JP JP5051911A patent/JPH0649052A/ja active Pending
-
1995
- 1995-12-07 AU AU40289/95A patent/AU4028995A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
MY111178A (en) | 1999-09-30 |
YU16893A (sh) | 1996-07-24 |
US5169860A (en) | 1992-12-08 |
KR930019655A (ko) | 1993-10-18 |
CZ36893A3 (en) | 1994-04-13 |
FI931085A0 (fi) | 1993-03-11 |
MX9301296A (es) | 1993-10-01 |
AU4028995A (en) | 1996-02-15 |
BR9301137A (pt) | 1993-09-28 |
CN1076447A (zh) | 1993-09-22 |
EP0560554A3 (ja) | 1994-01-19 |
JPH0649052A (ja) | 1994-02-22 |
FI931085A (fi) | 1993-09-14 |
EP0560554A2 (en) | 1993-09-15 |
AU662605B2 (en) | 1995-09-07 |
TW215083B (ja) | 1993-10-21 |
NZ247083A (en) | 1995-09-26 |
IL104981A0 (en) | 1993-07-08 |
AU3519893A (en) | 1993-09-16 |
NO930891D0 (no) | 1993-03-11 |
CA2091207A1 (en) | 1993-09-14 |
HU9300688D0 (en) | 1993-05-28 |
ZA931645B (en) | 1994-09-08 |
NO930891L (no) | 1993-09-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
DFC4 | Cancellation of temporary protection due to refusal |