HUT60465A - Process for producing carboxylic acid amides and pharmaceutical compositions comprising such active ingredient - Google Patents
Process for producing carboxylic acid amides and pharmaceutical compositions comprising such active ingredient Download PDFInfo
- Publication number
- HUT60465A HUT60465A HU9200871A HU9200871A HUT60465A HU T60465 A HUT60465 A HU T60465A HU 9200871 A HU9200871 A HU 9200871A HU 9200871 A HU9200871 A HU 9200871A HU T60465 A HUT60465 A HU T60465A
- Authority
- HU
- Hungary
- Prior art keywords
- tetrahydro
- oxo
- benzoic acid
- carboxamido
- trimethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH86391 | 1991-03-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HU9200871D0 HU9200871D0 (en) | 1992-05-28 |
| HUT60465A true HUT60465A (en) | 1992-09-28 |
Family
ID=4196940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9200871A HUT60465A (en) | 1991-03-21 | 1992-03-16 | Process for producing carboxylic acid amides and pharmaceutical compositions comprising such active ingredient |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5216148A (online.php) |
| EP (1) | EP0504695A1 (online.php) |
| JP (1) | JPH07165709A (online.php) |
| KR (1) | KR920018029A (online.php) |
| AU (1) | AU649308B2 (online.php) |
| BR (1) | BR9200951A (online.php) |
| CA (1) | CA2061662A1 (online.php) |
| CS (1) | CS83892A3 (online.php) |
| FI (1) | FI921135A7 (online.php) |
| HU (1) | HUT60465A (online.php) |
| IE (1) | IE920907A1 (online.php) |
| IL (1) | IL101242A (online.php) |
| IS (1) | IS3823A (online.php) |
| MX (1) | MX9201143A (online.php) |
| MY (1) | MY131268A (online.php) |
| NO (1) | NO921105L (online.php) |
| NZ (1) | NZ241953A (online.php) |
| TW (1) | TW221425B (online.php) |
| UY (1) | UY23386A1 (online.php) |
| YU (1) | YU24792A (online.php) |
| ZA (1) | ZA921889B (online.php) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5599548A (en) * | 1995-05-08 | 1997-02-04 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing fatty acid amides and retinol or retinyl ester |
| ZA9610853B (en) * | 1995-12-29 | 1998-04-06 | Smithkline Beecham Corp | Processes and intermediates for preparing pharmaceuticals. |
| US5716627A (en) * | 1996-04-25 | 1998-02-10 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing fatty acid amides, azoles, and retinol or retinyl ester |
| US5693330A (en) * | 1996-04-25 | 1997-12-02 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing melinamide and a retinoid |
| US5955092A (en) * | 1996-09-27 | 1999-09-21 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing an n-substituted fatty acid amide and retinol or retinyl ester |
| US5747051A (en) * | 1996-09-27 | 1998-05-05 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing an amide of a hydroxy fatty acid and a retinoid |
| US20060025388A1 (en) | 1999-04-30 | 2006-02-02 | Glick Gary D | Compositions and methods relating to novel compounds and targets thereof |
| US20040176358A1 (en) * | 1999-04-30 | 2004-09-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| ATE433752T1 (de) | 1999-04-30 | 2009-07-15 | Univ Michigan | Verwendung von benzodiazepinen zur behandlung von autoimmunischen krankheiten, entzündungen, neoplasien, viralen infektionen und atherosklerosis |
| US7144880B2 (en) | 1999-04-30 | 2006-12-05 | Regents Of The University Of Michigan | Compositions relating to novel compounds and targets thereof |
| US20050113460A1 (en) * | 1999-04-30 | 2005-05-26 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| JP2003514022A (ja) * | 1999-11-18 | 2003-04-15 | アンテックスファーマ・インコーポレーテッド | 置換された１−ベンズアゼピンとその誘導体 |
| TW200508197A (en) * | 2003-03-31 | 2005-03-01 | Ucb Sa | Indolone-acetamide derivatives, processes for preparing them and their uses |
| US20050202055A1 (en) * | 2004-03-11 | 2005-09-15 | Koichi Shudo, Tokyo, Japan | Anti-wrinkle agent |
| US20050272723A1 (en) * | 2004-04-27 | 2005-12-08 | The Regents Of The University Of Michigan | Methods and compositions for treating diseases and conditions associated with mitochondrial function |
| US20060052369A1 (en) * | 2004-09-07 | 2006-03-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| JP2008528448A (ja) * | 2005-01-03 | 2008-07-31 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 新規化合物に関連する組成物および方法、ならびにその標的 |
| WO2007053193A2 (en) | 2005-06-01 | 2007-05-10 | The Regents Of The University Of Michigan | Unsolvated benzodiazepine compositions and methods |
| US20070105844A1 (en) * | 2005-10-26 | 2007-05-10 | Regents Of The University Of Michigan | Therapeutic compositions and methods |
| NZ568254A (en) | 2005-11-01 | 2011-06-30 | Univ Michigan | 1,4-Benzodiazepine-2,5-diones for regulating cell death and treating autoimmune diseases |
| US7759338B2 (en) * | 2006-04-27 | 2010-07-20 | The Regents Of The University Of Michigan | Soluble 1,4 benzodiazepine compounds and stable salts thereof |
| EP2418206A3 (en) | 2006-06-09 | 2012-06-27 | The Regents of the University of Michigan | Benzodiazepine derivatives useful in the treatment of autoimmune disorders |
| CA2680017C (en) | 2007-03-09 | 2013-11-12 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| CN101855203B (zh) | 2007-09-14 | 2014-03-19 | 密执安州立大学董事会 | F1f0-atp合成酶抑制剂以及相关的方法 |
| UA99839C2 (ru) | 2007-11-06 | 2012-10-10 | Дзе Риджентс Оф Дзе Юниверсити Оф Мичиган | Бензодиазепиноновые соединения, применяемые при лечении кожных состояний |
| MY156226A (en) | 2008-02-22 | 2016-01-29 | Otsuka Pharma Co Ltd | Benzodiazepine compound and pharmaceutical composition |
| EP2352724B1 (en) | 2008-09-11 | 2015-04-22 | The Regents of the University of Michigan | Aryl guanidine f1f0-atpase inhibitors and their medical use |
| US8604023B2 (en) | 2009-04-17 | 2013-12-10 | The Regents Of The University Of Michigan | 1,4-benzodiazepinone compounds and their use in treating cancer |
| US8796447B2 (en) | 2009-08-21 | 2014-08-05 | Otsuka Pharmaceutical Co., Ltd. | Process for producing benzo[B][1,4]diazepine-2,4-dione compound |
| TWI481601B (zh) | 2009-08-21 | 2015-04-21 | Otsuka Pharma Co Ltd | 含氮化合物及藥學組成物 |
| WO2011035124A1 (en) | 2009-09-18 | 2011-03-24 | The Regents Of The University Of Michigan | Benzodiazepinone compounds and methods of treatment using same |
| JP5856064B2 (ja) | 2009-11-17 | 2016-02-09 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 治療特性を有する１，４−ベンゾジアゼピン−２，５−ジオンおよび関連化合物 |
| EP2501387B1 (en) | 2009-11-17 | 2016-07-27 | The Regents Of The University Of Michigan | 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties |
| WO2011137089A1 (en) | 2010-04-29 | 2011-11-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Activators of human pyruvate kinase |
| JP2012184225A (ja) * | 2011-02-18 | 2012-09-27 | Otsuka Pharmaceut Co Ltd | 医薬組成物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3803775A1 (de) * | 1988-02-09 | 1989-08-17 | Boehringer Mannheim Gmbh | Neue substituierte lactame, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
| DE3818830A1 (de) * | 1988-06-03 | 1989-12-14 | Boehringer Mannheim Gmbh | Bicyclische carboxamide, verfahren zu ihrer herstellung, deren vorstufen, und diese verbindungen enthaltende arzneimittel |
| AU626881B2 (en) * | 1988-07-14 | 1992-08-13 | F. Hoffmann-La Roche Ag | Benzofused heterocyclics used as pharmaceuticals |
-
1991
- 1991-03-19 BR BR929200951A patent/BR9200951A/pt not_active Application Discontinuation
-
1992
- 1992-02-20 AU AU11089/92A patent/AU649308B2/en not_active Ceased
- 1992-02-20 TW TW081101237A patent/TW221425B/zh active
- 1992-02-21 CA CA002061662A patent/CA2061662A1/en not_active Abandoned
- 1992-02-27 US US07/842,662 patent/US5216148A/en not_active Expired - Fee Related
- 1992-03-09 EP EP92103970A patent/EP0504695A1/de not_active Withdrawn
- 1992-03-12 YU YU24792A patent/YU24792A/sh unknown
- 1992-03-13 NZ NZ241953A patent/NZ241953A/en unknown
- 1992-03-13 ZA ZA921889A patent/ZA921889B/xx unknown
- 1992-03-16 MX MX9201143A patent/MX9201143A/es not_active IP Right Cessation
- 1992-03-16 IL IL10124292A patent/IL101242A/en not_active IP Right Cessation
- 1992-03-16 HU HU9200871A patent/HUT60465A/hu unknown
- 1992-03-17 FI FI921135A patent/FI921135A7/fi not_active Application Discontinuation
- 1992-03-17 JP JP4090152A patent/JPH07165709A/ja active Pending
- 1992-03-19 MY MYPI92000458A patent/MY131268A/en unknown
- 1992-03-19 CS CS92838A patent/CS83892A3/cs unknown
- 1992-03-20 NO NO92921105A patent/NO921105L/no unknown
- 1992-03-20 UY UY23386A patent/UY23386A1/es not_active IP Right Cessation
- 1992-03-20 IS IS3823A patent/IS3823A/is unknown
- 1992-03-20 IE IE090792A patent/IE920907A1/en unknown
- 1992-03-20 KR KR1019920004612A patent/KR920018029A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| YU24792A (sh) | 1994-09-09 |
| AU1108992A (en) | 1992-09-24 |
| IL101242A (en) | 1995-12-08 |
| AU649308B2 (en) | 1994-05-19 |
| MY131268A (en) | 2007-07-31 |
| NZ241953A (en) | 1994-11-25 |
| US5216148A (en) | 1993-06-01 |
| EP0504695A1 (de) | 1992-09-23 |
| CS83892A3 (en) | 1992-10-14 |
| BR9200951A (pt) | 1992-11-17 |
| KR920018029A (ko) | 1992-10-21 |
| IE920907A1 (en) | 1992-09-23 |
| IS3823A (is) | 1992-09-22 |
| FI921135L (fi) | 1992-09-22 |
| CA2061662A1 (en) | 1992-09-22 |
| HU9200871D0 (en) | 1992-05-28 |
| JPH07165709A (ja) | 1995-06-27 |
| UY23386A1 (es) | 1992-11-05 |
| IL101242A0 (en) | 1992-11-15 |
| NO921105D0 (no) | 1992-03-20 |
| FI921135A0 (fi) | 1992-03-17 |
| ZA921889B (en) | 1992-11-25 |
| NO921105L (no) | 1992-09-22 |
| FI921135A7 (fi) | 1992-09-22 |
| TW221425B (online.php) | 1994-03-01 |
| MX9201143A (es) | 1992-10-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DFC4 | Cancellation of temporary protection due to refusal |