HUT51632A - Process for producing derivatives of alkyl-phospho- and phosphono-serine as well as pharmaceutical preparations containing such compounds - Google Patents

Process for producing derivatives of alkyl-phospho- and phosphono-serine as well as pharmaceutical preparations containing such compounds

Info

Publication number
HUT51632A
HUT51632A HU891892A HU189289A HUT51632A HU T51632 A HUT51632 A HU T51632A HU 891892 A HU891892 A HU 891892A HU 189289 A HU189289 A HU 189289A HU T51632 A HUT51632 A HU T51632A
Authority
HU
Hungary
Prior art keywords
phosphono
phospho
serine
alkyl
compounds
Prior art date
Application number
HU891892A
Other languages
English (en)
Other versions
HU204278B (en
Inventor
Brachwitz Hans Dr
Reinhild Schonfeld
Langen Peter Dr
Paltauf Friedrich Dr
Hermetter Albin Dr
Original Assignee
Akad Wissenschaften Ddr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DD31486888A external-priority patent/DD299727A7/de
Priority claimed from DD31835988A external-priority patent/DD289892A7/de
Application filed by Akad Wissenschaften Ddr filed Critical Akad Wissenschaften Ddr
Publication of HUT51632A publication Critical patent/HUT51632A/hu
Publication of HU204278B publication Critical patent/HU204278B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/113—Esters of phosphoric acids with unsaturated acyclic alcohols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4071—Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4075—Esters with hydroxyalkyl compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HU891892A 1988-04-19 1989-04-18 Processs for producingalkyl-phospho- and -phosphono-serine derivatives and pharmaceutical compositions containing them HU204278B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DD31486888A DD299727A7 (de) 1988-04-19 1988-04-19 Alkyl- und alkenylphospho-l-serine, verfahren zu ihrer herstellung und verwendung
DD31835988A DD289892A7 (de) 1988-07-27 1988-07-27 Verfahren zur herstellung von alkylphosphonserinen

Publications (2)

Publication Number Publication Date
HUT51632A true HUT51632A (en) 1990-05-28
HU204278B HU204278B (en) 1991-12-30

Family

ID=25748200

Family Applications (1)

Application Number Title Priority Date Filing Date
HU891892A HU204278B (en) 1988-04-19 1989-04-18 Processs for producingalkyl-phospho- and -phosphono-serine derivatives and pharmaceutical compositions containing them

Country Status (11)

Country Link
US (1) US5155099A (hu)
EP (2) EP0338407B1 (hu)
JP (1) JPH03504965A (hu)
DE (1) DE58904595D1 (hu)
DK (1) DK167810B1 (hu)
ES (1) ES2056998T3 (hu)
FI (1) FI91966C (hu)
GR (1) GR3008598T3 (hu)
HU (1) HU204278B (hu)
NO (1) NO177712C (hu)
WO (1) WO1989010370A1 (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5117034A (en) * 1989-10-24 1992-05-26 Fuji Photo Film Co., Ltd. Phosphatidylserine derivatives
EP0581793A1 (en) * 1991-04-25 1994-02-09 University Of British Columbia Phosphonates and phosphinates as anti-cancer, -inflammatory, -allergy and -myocarditis agents
US5369097A (en) * 1991-04-25 1994-11-29 The University Of British Columbia Phosphonates as anti-cancer agents
US5506217A (en) * 1991-04-25 1996-04-09 The University Of British Columbia Phosphonates as anti-cancer agents
DE4132344A1 (de) * 1991-09-27 1993-04-01 Max Planck Gesellschaft Verfahren zur herstellung eines arzneimittels zur oralen oder topischen verabreichung bei der behandlung von leishmaniasis
US6254879B1 (en) * 1991-09-27 2001-07-03 Max-Planck-Gessellschaft zun Förderung der Wissenschaften e.V. Methods of treating protozoal diseases
DE4229877C2 (de) * 1992-09-04 1994-09-15 Max Delbrueck Centrum Phospho- bzw. Phosphono-(N-acyl)-serine und ihre Herstellung
WO2003024423A1 (en) * 2001-09-18 2003-03-27 Vasogen Ireland Limited Apoptosis-mimicking synthetic entities and use thereof in medical treatment
US6878532B1 (en) 2003-04-28 2005-04-12 Sioux Biochemical, Inc. Method of producing phosphatidylserine
EP1963343A1 (en) * 2005-12-14 2008-09-03 Novo Nordisk A/S Polypeptide protracting tags

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD238979A1 (de) * 1985-07-03 1986-09-10 Akad Wissenschaften Ddr Verfahren zur herstellung von o-alkylglycerophosphoserin-analogen
DD238978A1 (de) * 1985-07-03 1986-09-10 Akad Wissenschaften Ddr Verfahren zur herstellung von 2-o-alkyl-i-des oxy-1-halogenglycero-3-phospho-l-serinen
US4916249A (en) * 1985-07-03 1990-04-10 Hans Brachwitz Glycero-3(2)-phospho-L-serine derivatives and salts thereof
DD239405A1 (de) * 1985-07-15 1986-09-24 Akad Wissenschaften Ddr Verfahren zur herstellung von trifluoralkyl-glycerophospho-l-serinen
US4751320A (en) * 1985-11-27 1988-06-14 Kao Corporation Phosphoric ester and process for producing same
JPH064651B2 (ja) * 1985-11-27 1994-01-19 花王株式会社 リン酸エステルおよびその製造方法
DE3606633A1 (de) * 1986-02-28 1987-09-03 Max Planck Gesellschaft Neue phosphoverbindungen und diese enthaltende arzneimittel
JPH0761276B2 (ja) * 1986-11-14 1995-07-05 名糖産業株式会社 酵素法リン脂質−ｄ−セリン誘導体の製造法

Also Published As

Publication number Publication date
HU204278B (en) 1991-12-30
JPH03504965A (ja) 1991-10-31
GR3008598T3 (hu) 1993-10-29
FI91966C (fi) 1994-09-12
DK167810B1 (da) 1993-12-20
NO177712C (no) 1995-11-08
FI91966B (fi) 1994-05-31
DK250090A (da) 1990-10-17
DK250090D0 (da) 1990-10-17
NO904416L (no) 1990-10-12
EP0338407B1 (de) 1993-06-09
EP0413700A1 (de) 1991-02-27
NO904416D0 (no) 1990-10-12
DE58904595D1 (de) 1993-07-15
US5155099A (en) 1992-10-13
NO177712B (no) 1995-07-31
WO1989010370A1 (en) 1989-11-02
EP0338407A1 (de) 1989-10-25
ES2056998T3 (es) 1994-10-16
FI905051A0 (fi) 1990-10-15

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Legal Events

Date Code Title Description
HPC4 Succession in title of patentee

Owner name: HAFSLUND NYCOMED PHARMA AG., AT

HPC4 Succession in title of patentee

Owner name: ASTA MEDICA AG., DE

HMM4 Cancellation of final prot. due to non-payment of fee