HUT51269A - Process for producing benzimidazole derivatives and pharmaceutical compositions comprising same - Google Patents

Process for producing benzimidazole derivatives and pharmaceutical compositions comprising same

Info

Publication number
HUT51269A
HUT51269A HU876196A HU619687A HUT51269A HU T51269 A HUT51269 A HU T51269A HU 876196 A HU876196 A HU 876196A HU 619687 A HU619687 A HU 619687A HU T51269 A HUT51269 A HU T51269A
Authority
HU
Hungary
Prior art keywords
same
pharmaceutical compositions
benzimidazole derivatives
producing benzimidazole
producing
Prior art date
Application number
HU876196A
Other languages
English (en)
Other versions
HU204814B (en
Inventor
Tomas B Alminger
Rolf A Bergman
Hans Bundgaard
Per L Lindberg
Gunnel E Sunden
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE8604998A external-priority patent/SE8604998D0/xx
Priority claimed from SE8605551A external-priority patent/SE8605551D0/xx
Priority claimed from SE8704049A external-priority patent/SE8704049D0/xx
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of HUT51269A publication Critical patent/HUT51269A/hu
Publication of HU204814B publication Critical patent/HU204814B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
HU876196A 1986-11-21 1987-11-20 Process for producing benzimidazole derivatives and pharmaceutical compositions comprising same HU204814B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE8604998A SE8604998D0 (sv) 1986-11-21 1986-11-21 Novel pharmacological compounds
SE8605551A SE8605551D0 (sv) 1986-12-23 1986-12-23 Novel pharmacological compounds
SE8704049A SE8704049D0 (sv) 1987-10-16 1987-10-16 Novel pharmacological compounds
PCT/SE1987/000546 WO1988003921A1 (en) 1986-11-21 1987-11-20 New benzimidazole derivatives a process for production thereof and a pharmaceutical composition containing the same

Publications (2)

Publication Number Publication Date
HUT51269A true HUT51269A (en) 1990-04-28
HU204814B HU204814B (en) 1992-02-28

Family

ID=27355365

Family Applications (1)

Application Number Title Priority Date Filing Date
HU876196A HU204814B (en) 1986-11-21 1987-11-20 Process for producing benzimidazole derivatives and pharmaceutical compositions comprising same

Country Status (24)

Country Link
EP (3) EP0332647A1 (hu)
JP (1) JPH02500744A (hu)
KR (1) KR890700125A (hu)
AT (1) ATE84032T1 (hu)
AU (1) AU612129B2 (hu)
DE (1) DE3783356T2 (hu)
DK (1) DK365488D0 (hu)
EG (1) EG18379A (hu)
ES (1) ES2052603T3 (hu)
FI (1) FI892454A (hu)
GR (1) GR3007385T3 (hu)
HU (1) HU204814B (hu)
IE (2) IE61178B1 (hu)
IL (1) IL84504A (hu)
IS (1) IS1565B (hu)
LV (1) LV10954B (hu)
MY (1) MY101784A (hu)
NO (1) NO173998C (hu)
NZ (2) NZ234564A (hu)
PL (1) PL157655B1 (hu)
PT (1) PT86186B (hu)
RU (1) RU2062778C1 (hu)
WO (1) WO1988003921A1 (hu)
YU (1) YU47116B (hu)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8801907D0 (sv) * 1988-05-20 1988-05-20 Haessle Ab Novel pharmacological compounds
AU617217B2 (en) * 1988-09-20 1991-11-21 Hisamitsu Pharmaceutical Co., Inc. Novel dibenz(b,e)oxepin derivatives
IE64199B1 (en) * 1988-12-22 1995-07-12 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
US5049674A (en) * 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
JP3049367B2 (ja) * 1990-06-20 2000-06-05 アストラゼネカ・アクチエボラーグ ジアルコキシ−ピリジニル−ベンズイミダゾール誘導体、その製造方法およびそれを含む医薬
CA2053527C (en) * 1990-10-17 2002-03-12 Takashi Sohda Pyridine derivatives, their production and use
SE9103776D0 (sv) * 1991-12-19 1991-12-19 Astra Ab New compounds
EP0604657B1 (en) * 1992-05-21 2000-01-12 Otsuka Pharmaceutical Factory, Inc. Phosphonic diester derivative
WO1994026279A1 (en) * 1993-05-18 1994-11-24 The Upjohn Company Bisphosphonate esters for treating gastric disorders
US6875872B1 (en) 1993-05-28 2005-04-05 Astrazeneca Compounds
US6051570A (en) * 1997-05-30 2000-04-18 Dr. Reddy's Research Foundation Benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them
CA2317008C (en) * 1997-12-31 2009-01-20 The University Of Kansas Water soluble prodrugs of tertiary amine containing drugs and methods of making thereof
US20020132819A1 (en) 1999-12-17 2002-09-19 Metcalf Chester A. Novel purinse
EP1334971A4 (en) * 2000-10-12 2004-05-12 Takeda Chemical Industries Ltd BENZIMIDAZOLE COMPOUNDS, METHOD FOR THE PRODUCTION AND USE THEREOF
WO2003027098A1 (fr) * 2001-09-25 2003-04-03 Takeda Chemical Industries, Ltd. Compose de benzymidazole, procede de production et d'utilisation de celui-ci
WO2007014846A1 (en) * 2005-07-28 2007-02-08 Intervet International B.V. Novel benzimidazole (thio) carbamates with antiparasitic activity and the synthesis thereof
CA3000985C (en) 2014-10-14 2023-01-31 The Board Of Trustees Of The Leland Stanford Junior University Method for treating neurodegenerative diseases
WO2017106050A1 (en) 2015-12-15 2017-06-22 The Board Of Trustees Of The Leland Stanford Junior University Method for preventing and/or treating aging-associated cognitive impairment and neuroinflammation
EP3833344A4 (en) 2018-08-06 2022-07-06 The Board of Trustees of the Leland Stanford Junior University 2-ARYLBENZIMIDAZOLE AS PPARGC1A ACTIVATORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
CN114302873A (zh) * 2019-08-20 2022-04-08 小野药品工业株式会社 具有s1p5受体激动活性的化合物的盐和晶形

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (hu) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
JPS5836312B2 (ja) * 1978-08-21 1983-08-08 日本電信電話株式会社 通信用平衡ケ−ブル線路の障害位置測定方式
JPS5687818A (en) * 1979-12-19 1981-07-16 Ishikawajima Harima Heavy Ind Co Ltd Reflex type position detector
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
JPS57137860A (en) * 1981-02-20 1982-08-25 Sumitomo Electric Ind Ltd Optical tachometer
JPS5999597A (ja) * 1982-11-30 1984-06-08 株式会社東芝 光学測定装置
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
JPS6020051U (ja) * 1983-07-19 1985-02-12 三洋電機株式会社 カセツト収納装置
AU568441B2 (en) 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
IL76839A (en) * 1984-10-31 1988-08-31 Byk Gulden Lomberg Chem Fab Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds

Also Published As

Publication number Publication date
NO173998C (no) 1994-03-02
DE3783356D1 (de) 1993-02-11
FI892454A0 (fi) 1989-05-19
MY101784A (en) 1992-01-17
HU204814B (en) 1992-02-28
GR3007385T3 (hu) 1993-07-30
PT86186A (en) 1987-12-01
EP0332647A1 (en) 1989-09-20
IL84504A (en) 1994-10-07
IS3284A7 (is) 1988-05-22
RU2062778C1 (ru) 1996-06-27
NZ222495A (en) 1991-04-26
WO1988003921A1 (en) 1988-06-02
FI892454A (fi) 1989-05-19
YU211087A (en) 1988-12-31
EP0279149B1 (en) 1992-12-30
EP0510719A1 (en) 1992-10-28
PT86186B (pt) 1990-08-31
EP0279149A2 (en) 1988-08-24
LV10954A (lv) 1995-12-20
YU47116B (sh) 1994-12-28
IE61178B1 (en) 1994-10-05
AU612129B2 (en) 1991-07-04
KR890700125A (ko) 1989-03-02
NO883229L (no) 1988-09-16
DK365488A (da) 1988-07-01
JPH02500744A (ja) 1990-03-15
EG18379A (en) 1992-11-30
ES2052603T3 (es) 1994-07-16
NZ234564A (en) 1991-04-26
EP0279149A3 (en) 1988-08-31
NO883229D0 (no) 1988-07-20
LV10954B (en) 1996-08-20
ATE84032T1 (de) 1993-01-15
IE940326L (en) 1988-05-21
DK365488D0 (da) 1988-07-01
AU8330287A (en) 1988-06-16
NO173998B (no) 1993-11-22
PL157655B1 (pl) 1992-06-30
IS1565B (is) 1994-12-13
PL268927A1 (en) 1989-01-23
DE3783356T2 (de) 1993-04-15
IE873125L (en) 1988-05-21

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee